Opportunity Information: Apply for PA 16 180
Apply for PA 16 180
- The HHS-NIH11 in the health sector is offering a public funding opportunity titled "Development and Commercialization of Technologies to Create, Characterize or Improve Animal Models of Human Disease (R43/R44)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.351,.
- This funding opportunity was created on Apr 11, 2016 and posted on Apr 11, 2016.
- Applicants must submit their applications by Apr 05, 2019. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: Small businesses.
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Opportunity Summary:
The grant opportunity titled "Development and Commercialization of Technologies to Create, Characterize or Improve Animal Models of Human Disease (R43/R44)" is a Small Business Innovation Research (SBIR) funding announcement from the NIH Office of Research Infrastructure Programs (ORIP), within HHS-NIH. It is designed for eligible small business concerns that want to develop and commercialize new technologies that strengthen the nation s biomedical research infrastructure, specifically by improving the quality, usefulness, and accessibility of animal models of human disease and the biological materials that support those models. The overall focus is practical and translational: projects should not only advance scientific capability but also be oriented toward tools, platforms, or products that can be adopted by the research community to address emerging biomedical challenges.
ORIP s mission, as reflected in this announcement, centers on supporting research resources that create, develop, preserve, and distribute high-quality animal models and related biological materials. In plain terms, the agency is interested in innovations that make animal models more predictive, more standardized, easier to share, and better suited to studying human health and disease. This can include technologies that help generate new models, improve existing ones, or more rigorously characterize them so scientists can understand exactly what a model represents and how reliably it can be used across laboratories and studies. In addition to model development, the opportunity also highlights tools and devices that directly improve animal welfare, enhance handling practices, and simplify or modernize the management of animal facilities, reflecting the view that better welfare and better science are closely linked.
Because this is an R43/R44 SBIR opportunity, it supports the typical SBIR pathway from early-stage feasibility work (Phase I, R43) to more advanced research and development leading toward commercialization (Phase II, R44). The emphasis on commercialization means applicants are expected to be thinking beyond a one-off research project and toward a deliverable technology that can be disseminated, supported, and sustained, whether that is a novel animal model resource, a characterization platform, a breeding or colony management solution, a welfare-enhancing device, or another enabling product that serves the broader biomedical research enterprise.
Administratively, the opportunity is a discretionary grant program in the health funding category, listed under CFDA numbers 93.351, and it is specifically limited to small business applicants. The Funding Opportunity Announcement number is PA-16-180. It was created and posted on April 11, 2016, with a listed closing date of April 5, 2019. While the provided source data does not specify an award ceiling or expected number of awards, the intent of the program is clear: to stimulate innovative small-business driven R and D that improves animal model development and use, strengthens associated biological resources, and advances both human health research outcomes and the welfare of research animals.
Frequently Asked Questions (FAQs)
What is the title of this grant opportunity?
The opportunity is titled "Development and Commercialization of Technologies to Create, Characterize or Improve Animal Models of Human Disease (R43/R44)."
What type of funding program is this?
This is a Small Business Innovation Research (SBIR) funding announcement using the NIH SBIR mechanisms R43 (Phase I) and R44 (Phase II).
Which agency and office are offering this opportunity?
The opportunity is offered by the U.S. Department of Health and Human Services (HHS), National Institutes of Health (NIH), through the NIH Office of Research Infrastructure Programs (ORIP).
What is the main purpose of this SBIR opportunity?
The purpose is to support eligible small businesses in developing and commercializing new technologies that strengthen the nation's biomedical research infrastructure by improving the quality, usefulness, and accessibility of animal models of human disease and the biological materials that support those models.
What does ORIP focus on in this announcement?
ORIP focuses on practical, translational innovations that create, develop, preserve, and distribute high-quality animal models and related biological materials. The intent is to make animal models more predictive, more standardized, easier to share, and better suited for studying human health and disease.
Who is eligible to apply?
This opportunity is specifically limited to eligible small business concerns.
What kinds of projects are a good fit for this funding announcement?
Projects are expected to develop technologies that create new animal models, improve existing models, or more rigorously characterize models so researchers can understand what a model represents and how reliably it can be used across laboratories and studies. The emphasis is on practical tools, platforms, or products that can be adopted by the research community.
Does the opportunity support improving how animal models are characterized?
Yes. The announcement highlights technologies that characterize animal models more rigorously so scientists can better understand model attributes and ensure reliability and reproducibility across labs and studies.
Does this opportunity include work related to biological materials supporting animal models?
Yes. In addition to animal models themselves, the opportunity includes technologies that improve the biological materials that support those models, aligned with ORIP's mission of supporting high-quality resources.
Is commercialization required or expected?
Commercialization is a central emphasis. Applicants are expected to plan beyond a one-time research effort and toward a deliverable technology that can be disseminated, supported, and sustained for broader adoption by the biomedical research community.
How do the SBIR phases (R43 and R44) relate to this opportunity?
The opportunity follows the typical SBIR pathway: Phase I (R43) supports early-stage feasibility work, and Phase II (R44) supports more advanced research and development intended to move the technology toward commercialization.
What types of deliverables could result from projects under this opportunity?
Examples of deliverable outcomes described in the opportunity include a novel animal model resource, a characterization platform, a breeding or colony management solution, a welfare-enhancing device, or another enabling product that serves the broader biomedical research enterprise.
Does the announcement mention animal welfare or facility management technologies?
Yes. The opportunity highlights tools and devices that directly improve animal welfare, enhance handling practices, and simplify or modernize the management of animal facilities, reflecting the idea that better welfare and better science are closely linked.
What is the overall scientific and practical orientation of the funded work?
The overall orientation is practical and translational. Projects should advance scientific capability while also being oriented toward tools, platforms, or products that can be adopted by the research community to address emerging biomedical challenges.
What is the Funding Opportunity Announcement (FOA) number?
The FOA number is PA-16-180.
What is the CFDA number for this program?
The program is listed under CFDA number 93.351.
What is the funding category and grant type described?
It is described as a discretionary grant program in the health funding category.
When was this opportunity created and posted?
The announcement was created and posted on April 11, 2016.
What is the listed closing date?
The listed closing date is April 5, 2019.
Does the provided information specify an award ceiling or number of awards?
No. The provided source data does not specify an award ceiling or the expected number of awards.
What is the intended impact of the program based on the description?
The stated intent is to stimulate innovative small business-driven research and development that improves animal model development and use, strengthens associated biological resources, advances human health research outcomes, and improves the welfare of research animals.
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