Opportunity Information: Apply for RFA DD 12 005

  • The Centers for Disease Control and Prevention in the health sector is offering a public funding opportunity titled "Development and Evaluation of a Clinic Based Screening and Brief Intervention (SBI) for Changing Behaviors Related to Cytomegalovirus (CMV) Transmission in Pregnant Women" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.283 Centers for Disease Control and PreventionInvestigations and Technical Assistance.
  • This funding opportunity was created on Dec 9, 2011 and posted on Dec 9, 2011.
  • Applicants must submit their applications by Feb 10, 2012 500 PM U.S. Eastern Time. On time submission requires that electronic applications be error free and made available to CDC for processing from eRA Commons on or before the deadline date. Applications must be submitted to and validated successfully by Grants.gov/eRA Commons no later than 500 PM U.S. Eastern Time. Note HHS/CDC grant submission procedures do not provide a period of time beyond the application due date to correct any error or warning notices of noncompliance with application instructions that are identified by Grants.gov or eRA systems (i.e., error correction window).. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $500,000.00 to eligible and selected applicants.
  • Each selected applicant is eligible to receive up to $250,000.00 in funding.
  • The number of recipients for this funding is limited to 1 candidate(s).
  • Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
Apply for RFA DD 12 005

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Opportunity Summary:

This CDC funding opportunity (RFA DD 12 005) supported research to develop and test a clinic-based approach for reducing behaviors that increase the risk of cytomegalovirus (CMV) transmission during pregnancy. CMV is a common virus, and when infection occurs in pregnancy it can lead to congenital CMV, a major cause of hearing loss and other developmental problems in infants. The central goal of the project was practical and prevention-focused: figure out how to change day-to-day behaviors in pregnant women that contribute to CMV exposure, and do it in a way that can realistically be delivered in routine prenatal care without overburdening clinic staff.

The grant specifically called for a Screening and Brief Intervention (SBI) model delivered in prenatal care settings. In other words, the funded work was expected to build and evaluate a streamlined process where pregnant patients are screened for CMV-related risk behaviors and then receive a brief, targeted intervention aimed at reducing those risks. The emphasis on being “clinic based” and “brief” signals that CDC wanted something that could be embedded into normal workflows, similar to other brief counseling interventions used in clinical practice, rather than an intensive multi-session program that would be hard to sustain.

A key feature of the opportunity was implementation feasibility and acceptability. The research was not just about whether an intervention can change behavior under ideal conditions; it was also about whether it can be delivered by real prenatal care teams, fit within time and staffing constraints, and be acceptable to both patients and clinic personnel. The intended outcome was an intervention package that prenatal clinics could adopt as part of standard care, with clear procedures, training needs, and materials that support consistent delivery.

Administratively, the opportunity was offered by the Centers for Disease Control and Prevention as a discretionary cooperative agreement, meaning CDC anticipated substantial involvement with the awardee during the project (for example, collaboration on technical aspects, evaluation design, or dissemination). The funding activity category was health, and the CFDA listing associated with the program was 93.283 (CDC Investigations and Technical Assistance). The announcement anticipated one award, with an estimated total funding amount of $500,000. The award ceiling and floor were both set at $250,000, indicating a fixed annual or project-period amount per award consistent with making a single, standardized award.

Eligibility was described as unrestricted, open to any type of entity unless otherwise clarified in the full announcement. There was no cost sharing or matching requirement, which lowered barriers for applicants that might not have additional funds to contribute. The notice was posted December 9, 2011, with a submission deadline of February 10, 2012 at 5:00 PM Eastern Time. The submission language highlighted that applications had to be validated successfully through Grants.gov and eRA Commons by the deadline, and that CDC did not allow an additional “error correction window” after the due date, so applicants needed to ensure submissions were complete and error-free before the cutoff. The opportunity was archived February 11, 2012.

For applicants or organizations seeking more details at the time, CDC directed inquiries to its Procurement and Grants Office, Technical Information and Management Section (TIMS), with a general submission inquiries phone line. Overall, the grant’s focus was highly applied: build a behavioral prevention intervention that works in the real world of prenatal care, evaluate it, and contribute to lowering the incidence of congenital CMV by reducing preventable exposure risks during pregnancy.

Frequently Asked Questions (FAQs)

What is this CDC funding opportunity?

This opportunity (RFA DD 12 005) was a CDC discretionary cooperative agreement that supported research to develop and test a clinic-based approach to reduce behaviors that increase the risk of cytomegalovirus (CMV) transmission during pregnancy.

What public health problem was the grant trying to address?

The project focused on preventing congenital CMV by reducing preventable CMV exposure risks during pregnancy. CMV is a common virus, and infection during pregnancy can lead to congenital CMV, which is a major cause of hearing loss and other developmental problems in infants.

What was the main goal of the funded project?

The central goal was practical and prevention-focused: identify day-to-day behaviors in pregnant women that contribute to CMV exposure, and develop a way to change those behaviors that can realistically be delivered in routine prenatal care without overburdening clinic staff.

What kind of intervention model was CDC expecting?

The grant specifically called for a Screening and Brief Intervention (SBI) model delivered in prenatal care settings. This means pregnant patients would be screened for CMV-related risk behaviors and then receive a brief, targeted intervention aimed at reducing those risks.

What does "clinic-based" and "brief" mean in this context?

It means the approach was expected to fit into standard prenatal care workflows, similar to other brief counseling interventions used in clinical practice, rather than a time-intensive multi-session program that would be difficult for clinics to sustain.

Where was the intervention intended to be delivered?

The intervention was intended to be delivered in prenatal care settings, embedded within routine prenatal care.

What kinds of outcomes was the research aiming for?

The intended outcome was an intervention package that prenatal clinics could adopt as part of standard care, including clear procedures, training needs, and materials to support consistent delivery.

Was the grant only about whether the intervention works under ideal research conditions?

No. A key feature was implementation feasibility and acceptability. The funded work was expected to consider whether real prenatal care teams could deliver the intervention within time and staffing constraints, and whether it would be acceptable to both patients and clinic personnel.

What type of award mechanism was used?

It was offered as a discretionary cooperative agreement, meaning CDC anticipated substantial involvement with the awardee during the project (for example, collaboration on technical aspects, evaluation design, or dissemination).

What was the funding activity category?

The funding activity category was health.

What CFDA number was associated with this program?

The CFDA listing associated with the program was 93.283 (CDC Investigations and Technical Assistance).

How many awards were anticipated?

The announcement anticipated one award.

What was the estimated total funding amount?

The estimated total funding amount was $500,000.

What were the award ceiling and award floor?

The award ceiling was $250,000 and the award floor was also $250,000, indicating a fixed amount per award consistent with making a single, standardized award.

Who was eligible to apply?

Eligibility was described as unrestricted, meaning it was open to any type of entity unless otherwise clarified in the full announcement.

Was cost sharing or matching required?

No. There was no cost sharing or matching requirement.

When was the notice posted?

The notice was posted on December 9, 2011.

What was the application submission deadline?

The submission deadline was February 10, 2012 at 5:00 PM Eastern Time.

How were applications required to be submitted?

The submission language indicated applications had to be validated successfully through Grants.gov and eRA Commons by the deadline.

Was there an error correction window after the deadline?

No. CDC did not allow an additional "error correction window" after the due date, so applicants needed to ensure submissions were complete and error-free before the cutoff.

When was the opportunity archived?

The opportunity was archived on February 11, 2012.

Who could applicants contact for submission-related questions?

CDC directed inquiries to its Procurement and Grants Office, Technical Information and Management Section (TIMS), using a general submission inquiries phone line.

What was CDC ultimately trying to achieve through this project?

The overall focus was highly applied: build a behavioral prevention intervention that works in the real world of prenatal care, evaluate it, and contribute to lowering the incidence of congenital CMV by reducing preventable exposure risks during pregnancy.

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