Opportunity Information: Apply for RFA EB 14 001

  • The National Institutes of Health in the health sector is offering a public funding opportunity titled "Development and Translation of Medical Technologies to Reduce Health Disparities (SBIR) (R43/R44)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.286 Discovery and Applied Research for Technological Innovations to Improve Human Health 93.307 Minority Health and Health Disparities Research.
  • This funding opportunity was created on Oct 24, 2014 and posted on Feb 18, 2014.
  • Applicants must submit their applications by Oct 25, 2014. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $2,000,000.00 to eligible and selected applicants.
  • Eligible applicants include: Small businesses.
  • Other Eligible Applicants include the following Non domestic (non U.S.) Entities (Foreign Institutions) are not eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, may be allowed.
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Opportunity Summary:

The NIH funding opportunity titled "Development and Translation of Medical Technologies to Reduce Health Disparities (SBIR) (R43/R44)" (Funding Opportunity Number RFA-EB-14-001) is a discretionary grant program designed to support small businesses that are developing practical medical technologies specifically intended to reduce health disparities. The central goal is to move beyond early concepts and fund work that helps translate promising ideas into real-world tools that can improve healthcare access and outcomes for populations that experience disproportionate disease burden, poorer outcomes, or barriers to care. The announcement emphasizes that the proposed technologies should be not only clinically useful, but also realistic for the settings and communities they are intended to serve.

A key theme of the FOA is that technology alone is not enough; the proposed solution must be effective, affordable, culturally acceptable, and deliverable to the people who need it. In other words, applicants are expected to address the practical adoption issues that often prevent innovations from reaching underserved communities. Projects that account for cost constraints, workflow realities, usability, language and cultural factors, and the logistical barriers common in safety-net or resource-limited environments align strongly with the intent of the program. The opportunity is positioned to support development and translation activities typical of SBIR efforts, generally progressing from feasibility and early validation work in Phase I (R43) to more advanced development, refinement, and preparation for broader use in Phase II (R44).

An important eligibility and responsiveness requirement is formal collaboration with a healthcare provider or another healthcare organization that serves one or more health disparity populations, and that collaboration must be in place during both Phase I and Phase II. This requirement signals that NIH expects applicants to ground their development work in real clinical or community practice settings, with direct input and participation from organizations that understand the needs, constraints, and priorities of the populations experiencing disparities. For applicants, this means the partnership should be more than informal advice; it should be structured and documented in a way that demonstrates authentic engagement, such as roles in testing, implementation planning, recruitment, workflow integration, and evaluation.

The program is offered under the Small Business Innovation Research (SBIR) mechanism and uses the R43/R44 grant structure. Eligible applicants are small business concerns (small businesses). Foreign institutions are not eligible to apply, and non-U.S. components of U.S. organizations are also not eligible. However, foreign components, as defined by the NIH Grants Policy Statement, may be permitted in certain circumstances, which typically means specific project elements could potentially be performed abroad if adequately justified and allowable under NIH policy, while the applicant organization itself must remain eligible and U.S.-based.

From an administrative standpoint, the opportunity is run by the National Institutes of Health (NIH) and is categorized under health-related funding activities. It is associated with CFDA numbers 93.286 (Discovery and Applied Research for Technological Innovations to Improve Human Health) and 93.307 (Minority Health and Health Disparities Research). The FOA indicates no cost sharing or matching requirement, which is helpful for small businesses that may not have the resources to provide matching funds. The estimated total funding amount listed is $2,000,000, providing a general sense of the scale of support anticipated for awards made under this solicitation.

The key dates provided in the listing reflect that the FOA was posted February 18, 2014, created October 24, 2014, and ultimately archived November 24, 2014. The original closing date was January 7, 2015, while the current closing date shown is October 25, 2014, indicating the solicitation is no longer open. For full details, NIH provided an additional information link to the complete FOA on the NIH grants website, and the NIH Office of Extramural Research (OER) webmaster contact is listed for access or linking issues.

Overall, this FOA is aimed at small businesses that can demonstrate both a strong technological development plan and a credible pathway to real-world use in disparity-affected communities. The strongest proposals under this kind of announcement typically show a clear understanding of the targeted disparity population, strong implementation and usability considerations, and a meaningful partnership with organizations already delivering care to those communities so that the technology is built and tested in the environments where it is meant to make a difference.

FAQs: Development and Translation of Medical Technologies to Reduce Health Disparities (SBIR) (R43/R44) - RFA-EB-14-001

What is this NIH funding opportunity?

This is an NIH Small Business Innovation Research (SBIR) discretionary grant opportunity titled "Development and Translation of Medical Technologies to Reduce Health Disparities (SBIR) (R43/R44)." It is designed to support small businesses developing practical medical technologies intended to reduce health disparities.

What is the Funding Opportunity Number (FOA number)?

The Funding Opportunity Number is RFA-EB-14-001.

What is the main goal of the program?

The central goal is to move beyond early concepts and support development and translation work that helps turn promising ideas into real-world tools that improve healthcare access and outcomes for populations experiencing health disparities (such as disproportionate disease burden, poorer outcomes, or barriers to care).

Who is this program intended to help?

The program focuses on populations that experience health disparities, including groups facing disproportionate disease burden, poorer clinical outcomes, and/or systemic barriers to receiving care.

What kinds of projects fit this FOA best?

Projects that develop clinically useful technologies that are also realistic for the settings and communities they are meant to serve. The FOA emphasizes practical adoption factors such as affordability, deliverability, cultural acceptability, usability, and fit with real-world workflows in safety-net or resource-limited environments.

Is technology performance alone enough to be competitive?

No. The FOA highlights that technology alone is not enough; the solution should be effective, affordable, culturally acceptable, and deliverable to the people who need it. Applications are expected to address practical adoption issues that often prevent innovations from reaching underserved communities.

What specific real-world factors does NIH expect applicants to consider?

Based on the FOA description, strong alignment includes consideration of cost constraints, workflow realities, usability, language and cultural factors, and logistical barriers commonly found in safety-net or resource-limited settings.

What funding mechanism is used?

The opportunity uses the SBIR mechanism and the R43/R44 grant structure.

What do R43 and R44 generally represent in this FOA?

They reflect the typical SBIR progression described in the announcement: Phase I (R43) generally supports feasibility and early validation work, while Phase II (R44) supports more advanced development, refinement, and preparation for broader use.

Who is eligible to apply?

Eligible applicants are small business concerns (small businesses), consistent with the SBIR program mechanism described in the FOA summary.

Are foreign institutions eligible to apply?

No. Foreign institutions are not eligible to apply.

Can a U.S. organization include a non-U.S. component as part of the applicant?

No. Non-U.S. components of U.S. organizations are not eligible, according to the eligibility notes provided.

Are any foreign activities allowed at all?

Potentially, yes. The summary notes that foreign components (as defined by the NIH Grants Policy Statement) may be permitted in certain circumstances, typically meaning specific project elements could be performed abroad if adequately justified and allowable under NIH policy. The applicant organization itself must still be an eligible U.S.-based small business.

Is a collaboration with a healthcare organization required?

Yes. A formal collaboration is an important eligibility and responsiveness requirement. The collaboration must be with a healthcare provider or another healthcare organization that serves one or more health disparity populations.

Does the collaboration have to cover both Phase I and Phase II?

Yes. The FOA summary specifies that the collaboration must be in place during both Phase I and Phase II.

What does NIH mean by a "formal" collaboration in this context?

The description indicates the partnership should be more than informal advice. It should be structured and documented in a way that demonstrates authentic engagement, with clear roles such as participation in testing, implementation planning, recruitment, workflow integration, and evaluation.

Why is the collaboration requirement emphasized?

It signals that NIH expects the development work to be grounded in real clinical or community practice settings, with direct input and participation from organizations that understand the needs, constraints, and priorities of populations experiencing disparities.

Is cost sharing or matching required?

No. The listing indicates there is no cost sharing or matching requirement.

How much total funding is estimated under this solicitation?

The estimated total funding amount listed is $2,000,000.

Which agency runs this opportunity?

The program is run by the National Institutes of Health (NIH).

What CFDA numbers are associated with this FOA?

The opportunity is associated with CFDA 93.286 (Discovery and Applied Research for Technological Innovations to Improve Human Health) and 93.307 (Minority Health and Health Disparities Research).

Is this funding opportunity currently open?

No. The dates provided indicate the FOA has been archived (archived November 24, 2014). The listing shows an original closing date of January 7, 2015 and a current closing date of October 25, 2014, indicating it is no longer open for applications.

Where can someone find the full FOA details?

The summary notes that NIH provided an additional information link to the complete FOA on the NIH grants website.

Who is listed as a contact for access or linking issues?

The NIH Office of Extramural Research (OER) webmaster is listed as the contact for access or linking issues.

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