Opportunity Information: Apply for RFA EB 15 001

  • The National Institutes of Health in the health sector is offering a public funding opportunity titled "Development and Translation of Medical Technologies to Reduce Health Disparities (SBIR) (R43/R44)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.286 Discovery and Applied Research for Technological Innovations to Improve Human Health 93.307 Minority Health and Health Disparities Research.
  • This funding opportunity was created on Oct 24, 2014 and posted on Oct 24, 2014.
  • Applicants must submit their applications by Sep 7, 2015. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $2,000,000.00 to eligible and selected applicants.
  • Eligible applicants include: Small businesses.
  • Other Eligible Applicants include the following Only United States small business concerns (SBCs) are eligible to submit applications for this opportunity. A small business concern is one that, at the time of award of Phase I and Phase II, meets all of the following criteria 1. Is organized for profit, with a place of business located in the United States, which operates primarily within the United States or which makes a significant contribution to the United States economy through payment of taxes or use of American products, materials or labor 2. Is in the legal form of an individual proprietorship, partnership, limited liability company, corporation, joint venture, association, trust or cooperative, except that where the form is a joint venture, there must be less than 50 percent participation by foreign business entities in the joint venture 3. (i) SBIR and STTR. Be a concern which is more than 50 directly owned and controlled by one or more individuals (who are citizens or permanent resident aliens of the United States), other business concerns (each of which is more than 50 directly owned and controlled by individuals who are citizens or permanent resident aliens of the United States), or any combination of these OR (ii) SBIR only. Be a concern which is more than 50 owned by multiple venture capital operating companies, hedge funds, private equity firms, or any combination of these. No single venture capital operating company, hedge fund, or private equity firm may own more than 50 of the concern OR (iii) SBIR and STTR. Be a joint venture in which each entity to the joint venture must meet the requirements set forth in paragraph 3 (i) or 3 (ii) of this section. A joint venture that includes one or more concerns that meet the requirements of paragraph (ii) of this section must comply with 121.705(b) concerning registration and proposal requirements. 4. Has, including its affiliates, not more than 500 employees.
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Opportunity Summary:

Development and Translation of Medical Technologies to Reduce Health Disparities (SBIR) (R43/R44) is a National Institutes of Health (NIH) Small Business Innovation Research (SBIR) grant opportunity focused on helping small U.S. companies create and move forward practical medical technologies that can measurably reduce health disparities. The core purpose is to support technology development and translation work that improves both healthcare access and health outcomes for populations that experience disproportionate barriers or burdens in health. The announcement emphasizes solutions that are not only technically sound, but also realistic in the settings where disparities occur, meaning the technologies should be effective, affordable, culturally acceptable, and actually deliverable to the people who need them.

A defining requirement of this FOA is that applicants must build a formal collaboration with a healthcare provider or another healthcare organization that serves one or more health disparity populations, and that collaboration must be in place during both Phase I and Phase II. In practice, that means the small business is expected to work directly with real-world clinical or community-serving partners early, rather than developing in isolation. This collaboration is meant to strengthen the relevance, usability, and adoption potential of the technology by ensuring it fits the workflows, constraints, and cultural context of the intended users and care environments.

The funding instrument is a grant under the SBIR program using the R43/R44 mechanisms, which correspond to Phase I and Phase II SBIR awards. Phase I typically supports early feasibility work and proof-of-concept, while Phase II generally supports further development, validation, and steps needed to move the technology toward implementation and broader impact. The opportunity is categorized as discretionary funding and falls under health-related activity areas, specifically tied to CFDA numbers 93.286 (Discovery and Applied Research for Technological Innovations to Improve Human Health) and 93.307 (Minority Health and Health Disparities Research). The announcement indicates no cost sharing or matching requirement, which means applicants are not required to contribute non-federal matching funds as a condition of the award.

Eligibility is limited to United States small business concerns (SBCs). To qualify, a company must be organized for profit, have a place of business in the U.S., and operate primarily in the U.S. or otherwise make a significant contribution to the U.S. economy (for example through taxes or use of American labor and materials). The business must fit one of the allowed legal structures (such as an LLC or corporation), and it must have no more than 500 employees including affiliates. Ownership and control requirements follow standard SBIR rules, including pathways for majority ownership by U.S. citizens or permanent residents, as well as certain SBIR-allowable structures involving multiple venture capital operating companies, hedge funds, or private equity firms, provided no single such entity owns more than 50 percent. Joint ventures can be eligible if they meet the specified ownership and registration conditions described in the announcement.

From an administrative standpoint, this opportunity was posted and created on October 24, 2014, with an original and current closing date of September 7, 2015, and an archive date of October 8, 2015. The estimated total funding amount listed is $2,000,000. The official funding opportunity number is RFA-EB-15-001, and the full announcement was made available through NIH’s grants guide. For technical access or linking issues, the contact listed is the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.

Frequently Asked Questions (FAQ)

What is the name of this funding opportunity?

The opportunity is titled "Development and Translation of Medical Technologies to Reduce Health Disparities (SBIR) (R43/R44)."

Which agency is offering this grant?

This is a National Institutes of Health (NIH) funding opportunity under the Small Business Innovation Research (SBIR) program.

What is the core purpose of this SBIR FOA?

The purpose is to support U.S. small businesses in developing and translating practical medical technologies that can measurably reduce health disparities by improving healthcare access and health outcomes for populations experiencing disproportionate health burdens or barriers.

What kinds of solutions does the announcement emphasize?

The announcement emphasizes solutions that are technically sound and realistic in real-world settings where disparities occur. Technologies are expected to be effective, affordable, culturally acceptable, and deliverable to the people who need them.

What does "technology development and translation" mean in this FOA context?

Based on the description provided, the FOA supports work that moves a medical technology forward from development toward broader use and impact, including steps that help the technology fit real care settings and reach disparity populations.

What award mechanisms are used for this opportunity?

This FOA uses SBIR grant mechanisms R43 and R44, which correspond to Phase I and Phase II SBIR awards.

What is typically supported in SBIR Phase I under this FOA?

Phase I typically supports early feasibility work and proof-of-concept activities.

What is typically supported in SBIR Phase II under this FOA?

Phase II generally supports further development, validation, and other steps needed to move the technology toward implementation and broader impact.

Is collaboration with a healthcare organization required?

Yes. A defining requirement is that applicants must establish a formal collaboration with a healthcare provider or another healthcare organization that serves one or more health disparity populations.

Does the collaboration need to be in place during both Phase I and Phase II?

Yes. The formal collaboration must be in place during both Phase I and Phase II.

Why does the FOA require a formal collaboration partner?

The collaboration requirement is intended to ensure the technology is developed with real-world input so it fits the workflows, constraints, and cultural context of the intended users and care environments, strengthening relevance, usability, and adoption potential.

Who is eligible to apply?

Eligibility is limited to United States small business concerns (SBCs) that meet SBIR requirements.

What basic business characteristics are required for eligibility?

The company must be organized for profit, have a place of business in the U.S., and operate primarily in the U.S. or otherwise make a significant contribution to the U.S. economy (for example, through taxes or use of American labor and materials).

What is the employee size limit for an eligible small business?

The business must have no more than 500 employees, including affiliates.

Are specific legal structures allowed?

Yes. The business must fit one of the allowed legal structures described as examples in the announcement (such as an LLC or corporation).

How do ownership and control requirements work for this SBIR opportunity?

Ownership and control must follow standard SBIR rules. The information provided notes pathways for majority ownership by U.S. citizens or permanent residents, and certain SBIR-allowable structures involving multiple venture capital operating companies, hedge funds, or private equity firms, provided no single such entity owns more than 50 percent.

Can joint ventures apply?

Joint ventures can be eligible if they meet the specified ownership and registration conditions described in the announcement.

Is cost sharing or matching required?

No. The announcement indicates there is no cost sharing or matching requirement, meaning applicants are not required to contribute non-federal matching funds as a condition of the award.

What type of funding is this categorized as?

The opportunity is categorized as discretionary funding.

What activity area does this funding fall under?

It falls under health-related activity areas, tied to CFDA numbers 93.286 (Discovery and Applied Research for Technological Innovations to Improve Human Health) and 93.307 (Minority Health and Health Disparities Research).

What is the Funding Opportunity Number (FON)?

The Funding Opportunity Number is RFA-EB-15-001.

What is the estimated total funding amount listed?

The estimated total funding amount listed is $2,000,000.

When was this opportunity posted?

The opportunity was posted (and created) on October 24, 2014.

What was the closing date for applications?

The original and current closing date listed is September 7, 2015.

Is this funding opportunity still active?

Based on the dates provided, it was archived on October 8, 2015, indicating it is not currently active.

Where was the full announcement published?

The full announcement was made available through NIH's grants guide.

Who should be contacted for technical access or linking issues?

For technical access or linking issues, the contact listed is the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.

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