Opportunity Information: Apply for RFA DC 13 001

  • The National Institutes of Health in the health sector is offering a public funding opportunity titled "Development of a Vestibular Neural Prosthesis (R01)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.173 Research Related to Deafness and Communication Disorders.
  • This funding opportunity was created on Oct 18, 2013 and posted on Apr 3, 2012.
  • Applicants must submit their applications by Nov 1, 2013. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $1,000,000.00 to eligible and selected applicants.
  • Eligible applicants include: Public housing authorities/Indian housing authorities Small businesses County governments Private institutions of higher education Independent school districts State governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Special district governments Public and State controlled institutions of higher education Native American tribal governments (Federally recognized) Others (see text field entitled Additional Information on Eligibility for clarification) For profit organizations other than small businesses City or township governments Native American tribal organizations (other than Federally recognized tribal governments) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education.
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are not eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed
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Opportunity Summary:

The funding opportunity titled "Development of a Vestibular Neural Prosthesis (R01)" (Funding Opportunity Number RFA-DC-13-001) is a discretionary research grant offered by the National Institutes of Health (NIH), specifically through the National Institute on Deafness and Other Communication Disorders (NIDCD). It supports health-related research aimed at pushing vestibular neural prosthesis technology far enough along the development pipeline that it can move toward studies involving human subjects. The central purpose is translational: not simply exploring basic vestibular biology, but advancing an implantable or otherwise clinically relevant system that could eventually be tested in people.

The scientific focus is narrow and clearly defined. Applications are expected to pursue a vestibular neural prosthesis approach that uses electrical stimulation of the vestibular nerve to reduce or compensate for sensory impairments that occur when the vestibular endorgans are damaged or diseased. In other words, the announcement is aimed at technologies intended to restore or substitute vestibular sensory input by directly interfacing with the vestibular nerve. Projects that do not involve vestibular-nerve electrical stimulation, or that do not meaningfully advance prosthesis development toward human testing, would not fit the stated scope.

This opportunity uses the NIH R01 mechanism, which typically funds hypothesis-driven and development-focused research projects that can span multiple years and involve substantial, well-justified work plans. While the summary text emphasizes progression toward human subject studies, the announcement language indicates a development trajectory rather than requiring that human trials already be underway. A strong application would usually be expected to lay out a credible pathway toward human feasibility, including engineering readiness, preclinical validation, safety considerations, and practical steps needed to support eventual clinical translation.

The program falls under CFDA 93.173, "Research Related to Deafness and Communication Disorders," and it explicitly states there is no cost sharing or matching requirement. The estimated total funding amount listed is $1,000,000, which reflects the program’s overall anticipated allocation rather than a guaranteed amount per award. The opportunity was initially posted April 3, 2012, with key dates showing an original closing date of October 4, 2013, a current closing date of November 1, 2013, and an archive date of December 1, 2013.

Eligibility is broad across U.S.-based organizational types, spanning many public and private entities. Eligible applicants include state, county, city or township, and special district governments; public and state-controlled institutions of higher education; private institutions of higher education; independent school districts; public housing authorities and Indian housing authorities; nonprofits with 501(c)(3) status and nonprofits without 501(c)(3) status (with the specified caveat regarding institutions of higher education); small businesses and for-profit organizations other than small businesses; and Native American tribal governments (federally recognized) as well as tribal organizations that are not federally recognized. The eligibility information further clarifies that a range of mission-specific institutions and organizations are also eligible, including Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Alaska Native and Native Hawaiian-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), and faith-based or community-based organizations, along with regional organizations and U.S. territories or possessions. Foreign institutions are not eligible to apply, and non-U.S. components of U.S. organizations are also not eligible to apply, but foreign components (as NIH defines them in policy) are permitted.

Operationally, the announcement points applicants to the full solicitation text via an NIH grants guide link. For technical issues accessing or linking to the announcement, the contact provided is the NIH Office of Extramural Research (OER) webmaster at FBOWebmaster@OD.NIH.GOV. Overall, the opportunity is best understood as a targeted R01 meant to accelerate a very specific class of neural prosthetic intervention for vestibular dysfunction, with an emphasis on engineering and translational milestones that position the technology for near-term clinical evaluation in humans.

FAQs: Development of a Vestibular Neural Prosthesis (R01) (RFA-DC-13-001)

What is this funding opportunity?

This opportunity is a discretionary research grant from the National Institutes of Health (NIH), offered through the National Institute on Deafness and Other Communication Disorders (NIDCD). The funding opportunity is titled "Development of a Vestibular Neural Prosthesis (R01)" and has Funding Opportunity Number RFA-DC-13-001.

What is the main goal of the program?

The central goal is translational: to advance vestibular neural prosthesis technology far enough along the development pipeline that it can move toward studies involving human subjects. The intent is not simply basic exploration of vestibular biology, but progress toward an implantable or otherwise clinically relevant system that could eventually be tested in people.

What type of research approach is expected to be proposed?

Applications are expected to pursue a vestibular neural prosthesis approach that uses electrical stimulation of the vestibular nerve to reduce or compensate for sensory impairments that occur when vestibular endorgans are damaged or diseased. The focus is on restoring or substituting vestibular sensory input by directly interfacing with the vestibular nerve using electrical stimulation.

Are projects outside vestibular-nerve electrical stimulation responsive to this opportunity?

No. Projects that do not involve electrical stimulation of the vestibular nerve, or projects that do not meaningfully advance prosthesis development toward eventual human testing, do not fit the stated scope of this announcement.

What funding mechanism does this program use?

This opportunity uses the NIH R01 grant mechanism.

What does using an R01 mechanism imply for the project?

An R01 typically supports substantial, well-justified research plans that may be hypothesis-driven and/or development-focused and can span multiple years. For this specific opportunity, the emphasis is on development progress and translational milestones that position the technology for near-term clinical evaluation in humans.

Does the program require human trials to already be underway?

The provided description emphasizes progression toward human subject studies, but it indicates a development trajectory rather than requiring that human trials are already underway. A competitive application would generally be expected to present a credible pathway toward human feasibility.

What kinds of translational elements would a strong application typically include?

Based on the stated emphasis, a strong application would generally be expected to describe a credible pathway toward human feasibility, including items such as engineering readiness, preclinical validation, safety considerations, and practical steps needed to support eventual clinical translation.

Which NIH institute is sponsoring or administering the opportunity?

The opportunity is offered by NIH through the National Institute on Deafness and Other Communication Disorders (NIDCD).

What is the CFDA number and program area?

The program falls under CFDA 93.173, titled "Research Related to Deafness and Communication Disorders."

Is cost sharing or matching required?

No. The opportunity explicitly states there is no cost sharing or matching requirement.

How much funding is available under this opportunity?

The estimated total funding amount listed is $1,000,000. This reflects the program's overall anticipated allocation rather than a guaranteed amount per award.

When was the opportunity posted, and what are the key dates?

The opportunity was initially posted on April 3, 2012. Key dates include an original closing date of October 4, 2013; a current closing date of November 1, 2013; and an archive date of December 1, 2013.

Who is eligible to apply?

Eligibility is broad across many U.S.-based organizational types, including:

  • State governments
  • County governments
  • City or township governments
  • Special district governments
  • Public and state-controlled institutions of higher education
  • Private institutions of higher education
  • Independent school districts
  • Public housing authorities and Indian housing authorities
  • Nonprofits with 501(c)(3) status
  • Nonprofits without 501(c)(3) status (with the stated caveat regarding institutions of higher education)
  • Small businesses
  • For-profit organizations other than small businesses
  • Native American tribal governments (federally recognized)
  • Tribal organizations that are not federally recognized

Are mission-specific institutions and community organizations eligible?

Yes. The eligibility information specifically notes that a range of mission-specific institutions and organizations are eligible, including Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Alaska Native and Native Hawaiian-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), and faith-based or community-based organizations. Regional organizations and U.S. territories or possessions are also included.

Are foreign institutions eligible to apply?

No. Foreign institutions are not eligible to apply.

Are non-U.S. components of U.S. organizations eligible to apply?

No. Non-U.S. components of U.S. organizations are also not eligible to apply.

Are foreign components allowed at all?

Yes. While foreign institutions cannot apply and non-U.S. components of U.S. organizations are not eligible, foreign components (as NIH defines them in policy) are permitted.

Where can applicants find the full solicitation text?

The announcement directs applicants to the full solicitation text via an NIH grants guide link.

Who should be contacted for technical issues accessing or linking to the announcement?

For technical issues accessing or linking to the announcement, the contact provided is the NIH Office of Extramural Research (OER) webmaster at FBOWebmaster@OD.NIH.GOV.

In plain terms, what kinds of projects are the best fit for this RFA?

The best fit is an R01 project that directly advances a vestibular neural prosthesis based on electrical stimulation of the vestibular nerve, with clear engineering and translational milestones aimed at moving the technology toward near-term clinical evaluation in humans.

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