Opportunity Information: Apply for PA 13 145
Apply for PA 13 145
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Development of Animal Models and Related Biological Materials for Research (R21)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.351 Research Infrastructure Programs.
- This funding opportunity was created on Mar 19, 2013 and posted on Mar 19, 2013.
- Applicants must submit their applications by May 7, 2016. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $200,000.00 in funding.
- Eligible applicants include: Public housing authorities/Indian housing authorities Small businesses For profit organizations other than small businesses Independent school districts State governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education Public and State controlled institutions of higher education Native American tribal governments (Federally recognized) County governments Special district governments City or township governments Others (see text field entitled Additional Information on Eligibility for clarification) Native American tribal organizations (other than Federally recognized tribal governments) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
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Opportunity Summary:
The NIH Office of Research Infrastructure Programs (ORIP) released this Funding Opportunity Announcement, PA 13 145, titled "Development of Animal Models and Related Biological Materials for Research (R21)." It is a discretionary NIH grant opportunity in the health area (CFDA 93.351, Research Infrastructure Programs) that supports early-stage, exploratory research aimed at strengthening the animal-based resources that underpin biomedical science. In practical terms, the FOA invites applications that will develop new animal models, significantly improve existing models, or rigorously characterize models so they become more useful and reliable for studying human diseases. A second major emphasis is research that improves the diagnosis, prevention, and control of diseases that can affect research animals and disrupt or confound biomedical studies, ultimately improving the quality and reproducibility of research that depends on animal use.
The mechanism is an R21, meaning it is designed for exploratory or developmental projects that can establish feasibility, generate key proof-of-concept data, or open up new technical directions rather than support large, mature research programs. The listed award ceiling is $200,000, and there is no cost sharing or matching requirement. The opportunity was posted and created on March 19, 2013, with an original and final closing date of May 7, 2016, and it was archived on June 7, 2016. While it is no longer open, the summary still reflects how ORIP framed the kinds of model-development and animal health projects it wanted to stimulate during that period.
Eligibility is broad and includes many types of U.S. organizations and governments as well as international applicants. Eligible applicants include public and private institutions of higher education, public and state-controlled universities, and private universities. It also includes nonprofits with or without 501(c)(3) status (excluding those that are institutions of higher education where specified), small businesses, and for-profit organizations other than small businesses. Governmental entities across multiple levels are eligible, including state, county, city or township, special district governments, and Native American tribal governments and tribal organizations (including those that are not federally recognized). The FOA explicitly names additional eligible organizations such as historically underrepresented and mission-focused institutions (for example, HBCUs, Hispanic-serving institutions, tribally controlled colleges and universities, Alaska Native and Native Hawaiian serving institutions, and AANAPISIs), as well as faith-based or community-based organizations and eligible federal agencies. Importantly, non-U.S. entities are also eligible: foreign organizations and foreign institutions may apply, non-U.S. components of U.S. organizations are eligible, and foreign components (as defined by NIH policy) are allowed, reflecting an intention to encourage strong model and resource development work regardless of geography when it serves the NIH mission.
From a topic standpoint, the FOA centers on tangible improvements to research-enabling animal resources. This can include creating or refining animal models that better mirror human disease mechanisms, improving how those models are validated and characterized (for example, defining phenotypes, disease progression, or key biological readouts), and producing related biological materials that make models more usable by the broader research community. On the animal health side, it supports work that strengthens detection and control of infectious or other diseases in animal colonies, because such conditions can compromise animal welfare and introduce noise or bias into experimental results. Overall, the program aims to enhance the infrastructure of biomedical research by making animal models more accurate, better understood, and less vulnerable to confounding health issues.
Administrative and access details provided in the listing include a link to the full announcement on the NIH grants site (http://grants.nih.gov/grants/guide/pa-files/PA-13-145.html). For technical issues accessing the announcement or problems linking to the funding notice, the contact listed is the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.
FAQs: NIH ORIP Funding Opportunity PA-13-145 (R21)
What is this funding opportunity?
This is an NIH Office of Research Infrastructure Programs (ORIP) Funding Opportunity Announcement (FOA) titled "Development of Animal Models and Related Biological Materials for Research (R21)," identified as PA-13-145.
Which agency is offering this FOA?
The FOA was released by the National Institutes of Health (NIH), specifically through the NIH Office of Research Infrastructure Programs (ORIP).
What is the purpose of PA-13-145?
The FOA supports early-stage, exploratory research intended to strengthen animal-based resources used in biomedical research. It focuses on developing new animal models, significantly improving existing models, or rigorously characterizing models so they are more useful and reliable for studying human diseases. It also emphasizes work that improves the diagnosis, prevention, and control of diseases that affect research animals and can disrupt or confound studies.
What types of projects does the FOA invite?
Applications are invited for projects that:
- Develop new animal models relevant to human disease research
- Significantly improve existing animal models
- Rigorously characterize animal models (for example, defining phenotypes, disease progression, or key biological readouts) to increase usefulness and reliability
- Develop related biological materials that make animal models more usable by the broader research community
- Improve detection, diagnosis, prevention, and control of diseases in research animal colonies to reduce confounding effects and improve research quality and reproducibility
What is meant by "related biological materials" in this FOA?
Based on the listing, "related biological materials" refers to biological materials produced alongside animal model development or refinement that make models more usable by the broader research community.
Why does the FOA emphasize animal health (diagnosis, prevention, and control of disease in research animals)?
The FOA notes that diseases affecting research animals can disrupt or confound biomedical studies. Improving animal health monitoring and control can improve animal welfare and also improve the quality and reproducibility of research that depends on animal use.
What grant mechanism is used for this opportunity?
The mechanism is an NIH R21, which is designed for exploratory or developmental projects aimed at establishing feasibility, generating proof-of-concept data, or opening new technical directions rather than supporting large, mature research programs.
What is the award ceiling for PA-13-145?
The listed award ceiling is $200,000.
Is cost sharing or matching required?
No. The listing states there is no cost sharing or matching requirement.
What program area or category does this fall under?
It is described as a discretionary NIH grant opportunity in the health area, associated with CFDA 93.351 (Research Infrastructure Programs).
When was this FOA posted and when did it close?
The FOA was posted and created on March 19, 2013. The original and final closing date was May 7, 2016. It was archived on June 7, 2016.
Is this funding opportunity still open?
No. The listing indicates it is archived and is no longer open.
Who is eligible to apply?
Eligibility is broad and includes many U.S. organizations and governments as well as international applicants. The listing includes the following eligible applicant types:
- Public and private institutions of higher education
- Public and state-controlled universities
- Private universities
- Nonprofits with or without 501(c)(3) status (excluding those that are institutions of higher education where specified)
- Small businesses
- For-profit organizations other than small businesses
- State governments
- County governments
- City or township governments
- Special district governments
- Native American tribal governments and tribal organizations (including those that are not federally recognized)
- Historically underrepresented and mission-focused institutions (including HBCUs, Hispanic-serving institutions, tribally controlled colleges and universities, Alaska Native and Native Hawaiian serving institutions, and AANAPISIs)
- Faith-based or community-based organizations
- Eligible federal agencies
- Foreign organizations and foreign institutions
- Non-U.S. components of U.S. organizations
- Foreign components (as defined by NIH policy)
Are foreign (non-U.S.) organizations eligible?
Yes. The listing explicitly states that foreign organizations and foreign institutions may apply. It also states that non-U.S. components of U.S. organizations are eligible and that foreign components (as defined by NIH policy) are allowed.
Does the FOA limit eligibility to academic institutions only?
No. The listing includes eligibility for academic institutions, nonprofits, small businesses, for-profit organizations, and multiple levels of government entities, as well as other organization types specifically named.
Where can the full FOA text be found?
The listing provides a link to the full announcement on the NIH grants site: http://grants.nih.gov/grants/guide/pa-files/PA-13-145.html.
Who should be contacted for technical issues accessing the announcement?
For technical issues accessing the announcement or problems linking to the funding notice, the contact listed is the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.
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