Opportunity Information: Apply for RFA HL 11 034
Apply for RFA HL 11 034
- The National Institutes of Health in the education environment food and nutrition health income security and social services sector is offering a public funding opportunity titled "Development of Comprehensive and Conceptually based Measures of Psychosocial Stress (R21)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.113 Environmental Health 93.121 Oral Diseases and Disorders Research 93.142 NIEHS Hazardous Waste Worker Health and Safety Training 93.143 NIEHS Superfund Hazardous SubstancesBasic Research and Education 93.172 Human Genome Research 93.173 Research Related to Deafness and Communication Disorders 93.213 Research and Training in Complementary and Integrative Health 93.233 National Center on Sleep Disorders Research 93.242 Mental Health Research Grants 93.273 Alcohol Research Programs 93.279 Drug Abuse and Addiction Research Programs 93.286 Discovery and Applied Research for Technological Innovations to Improve Human Health 93.307 Minority Health and Health Disparities Research 93.361 Nursing Research 93.389 National Center for Research Resources 93.393 Cancer Cause and Prevention Research 93.394 Cancer Detection and Diagnosis Research 93.395 Cancer Treatment Research 93.396 Cancer Biology Research 93.399 Cancer Control 93.837 Cardiovascular Diseases Research 93.838 Lung Diseases Research 93.846 Arthritis, Musculoskeletal and Skin Diseases Research 93.847 Diabetes, Digestive, and Kidney Diseases Extramural Research 93.853 Extramural Research Programs in the Neurosciences and Neurological Disorders 93.855 Allergy, Immunology and Transplantation Research 93.856 Microbiology and Infectious Diseases Research 93.859 Biomedical Research and Research Training 93.865 Child Health and Human Development Extramural Research 93.866 Aging Research 93.867 Vision Research 93.879 Medical Library Assistance 93.989 International Research and Research Training.
- This funding opportunity was created on Aug 17, 2010 and posted on Aug 17, 2010.
- Applicants must submit their applications by Oct 14, 2010. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $1,050,000.00 to eligible and selected applicants.
- Each selected applicant is eligible to receive up to $200,000.00 in funding.
- Eligible applicants include: Public and State controlled institutions of higher education County governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education Special district governments Small businesses For profit organizations other than small businesses Public housing authorities/Indian housing authorities Independent school districts Others (see text field entitled Additional Information on Eligibility for clarification) Native American tribal governments (Federally recognized) Native American tribal organizations (other than Federally recognized tribal governments) State governments City or township governments.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:
The NIH Basic Behavioral and Social Sciences Opportunity Network (OppNet) released this Funding Opportunity Announcement, RFA-HL-11-034, to support early-stage research projects that build better ways to measure psychosocial stress. The central idea is not simply to create another survey or checklist, but to develop and test conceptually grounded, comprehensive measurement approaches that can be used across species (humans and animal models) and across the entire lifespan. The program is looking for measures that make stress research more comparable from one study to another and more useful for understanding how stress actually contributes to disease risk and health outcomes.
A major emphasis of the opportunity is improving what gets captured when researchers say they are measuring "stress." Applicants are encouraged to design measures that reflect real variation in stress exposures and experiences, including differences in chronicity (acute versus long-lasting stress), the contexts where stress occurs, and the pathways through which stress is perceived and processed. That includes environmental factors such as toxicant exposures as well as social environments, along with cognitive components (how people interpret or appraise stressors) and response components (behavioral, psychological, and physiological reactions). The FOA also highlights the need to account for factors that affect stress measurement across men and women and across developmental stages, so that tools remain meaningful for children, adolescents, adults, and older populations rather than being limited to one age group.
Another key theme is bridging research settings. The FOA calls for measurement work that connects laboratory-based designs with population-based designs, so that tools and constructs translate between controlled experiments and real-world epidemiologic or community studies. The expectation is that stronger measures, paired with these bridges, will clarify which components of psychosocial stressors are most relevant to disease processes and will support better cross-study comparability. In practice, that means the proposed work should do more than propose theory; it should demonstrate testing and validation steps that show the measure performs well and is interpretable across different study types and samples, potentially including parallel human and animal measures where appropriate.
The funding mechanism is the NIH R21, which is intended for exploratory and developmental research. Projects may request up to 2 years of support. The announcement states an estimated total funding level of about $1.05 million in FY 2011, with an anticipated 4 to 6 awards, depending on application quality and funds availability. The listed award ceiling is $200,000. Applicants are also instructed to include travel costs for the principal investigator to attend one 2-day grantee meeting each year, reflecting an expectation that funded teams will coordinate and share progress as part of an OppNet-supported portfolio.
Eligibility is broad and includes many types of domestic and non-domestic organizations. Eligible applicants include public and private institutions of higher education, nonprofits (with or without 501(c)(3) status), small businesses and other for-profit organizations (with some distinctions), and a range of government entities such as state, county, city/township, special district governments, independent school districts, and public housing authorities/Indian housing authorities. The eligibility section also explicitly includes groups such as historically black colleges and universities, Hispanic-serving institutions, tribally controlled colleges and universities, Alaska Native and Native Hawaiian serving institutions, federally recognized and other tribal governments and organizations, faith-based or community-based organizations, U.S. territories or possessions, and foreign organizations and regional organizations. There is no cost-sharing or matching requirement.
In terms of timing, the opportunity was posted on August 17, 2010, with an application deadline of October 14, 2010, and an archive date of November 14, 2010. The administering agency is the National Institutes of Health, and the FOA is tied to multiple CFDA program areas spanning environmental health, mental health, aging, cardiovascular and lung diseases, cancer, minority health and disparities, substance use, sleep, and other biomedical and behavioral research domains. That breadth underscores the main point of the announcement: improved, harmonized measures of psychosocial stress are viewed as foundational tools that can strengthen research across many health and disease areas, not just within one institute or specialty.
Frequently Asked Questions (FAQs)
What is this funding opportunity?
This is an NIH Basic Behavioral and Social Sciences Opportunity Network (OppNet) Funding Opportunity Announcement (FOA), RFA-HL-11-034, supporting early-stage research to develop and test improved ways to measure psychosocial stress.
What is the main goal of the FOA?
The goal is to build conceptually grounded, comprehensive measurement approaches for psychosocial stress that improve comparability across studies and help clarify how stress contributes to disease risk and health outcomes.
Is the FOA looking for new surveys or checklists?
Not in a simplistic sense. The FOA emphasizes that the aim is not merely to create another survey or checklist, but to develop and test well-grounded measurement approaches that better capture what researchers mean when they say they are measuring "stress."
What does the FOA mean by "conceptually grounded" measurement?
Based on the FOA description, measures should be rooted in clear concepts about psychosocial stress and its components, and then be tested and validated so the resulting tools are interpretable and useful across study designs and samples.
What aspects of stress should proposed measures capture?
The FOA encourages measures that reflect real variation in stress exposures and experiences, including differences in chronicity (acute versus long-lasting stress), the contexts where stress occurs, and pathways through which stress is perceived and processed.
Does the FOA care about stressor context and environment?
Yes. The FOA highlights the need to account for environmental factors (including toxicant exposures) and social environments as part of improved stress measurement.
Does the FOA include cognitive and response components of stress?
Yes. The FOA explicitly points to cognitive components (such as how people interpret or appraise stressors) and response components, including behavioral, psychological, and physiological reactions.
Are sex and gender differences relevant to this FOA?
Yes. The FOA highlights the need to account for factors affecting stress measurement across men and women so that resulting tools remain meaningful across populations.
Does the FOA expect measurement approaches to work across the lifespan?
Yes. A key emphasis is ensuring measures remain meaningful across developmental stages (children, adolescents, adults, and older populations), rather than being limited to a single age group.
Is cross-species measurement part of the program?
Yes. The FOA seeks approaches that can be used across species, including humans and animal models, to strengthen translation and comparability where appropriate.
Does the FOA require bridging lab-based and population-based research?
The FOA calls for measurement work that connects laboratory-based designs with population-based designs so that tools and constructs translate between controlled experiments and real-world epidemiologic or community studies.
What kinds of studies should the measures be usable in?
Based on the FOA description, measures should be suitable for both controlled laboratory studies and broader population-based studies, with an emphasis on translating constructs across these settings.
Is validation and testing expected, or is theory alone sufficient?
Testing and validation are expected. The FOA indicates the work should do more than propose theory and should demonstrate steps showing the measure performs well and is interpretable across different study types and samples.
What is the NIH funding mechanism for this opportunity?
The FOA uses the NIH R21 mechanism, which is intended for exploratory and developmental research.
How long can an R21 project last under this opportunity?
Projects may request up to 2 years of support.
What is the maximum award amount mentioned in the announcement?
The listed award ceiling is $200,000.
How much total funding was estimated for this FOA?
The announcement estimated a total funding level of about $1.05 million in FY 2011.
How many awards were anticipated?
The FOA anticipated 4 to 6 awards, depending on application quality and funds availability.
Are grantee meetings required?
The announcement instructs applicants to include travel costs for the principal investigator to attend one 2-day grantee meeting each year, indicating an expectation of coordination and progress-sharing within the OppNet-supported portfolio.
Who is eligible to apply?
Eligibility is broad and includes many domestic and non-domestic organizations, including higher education institutions, nonprofits, small businesses, for-profit organizations (with distinctions), and a wide range of government entities.
Are foreign organizations eligible?
Yes. The eligibility section explicitly includes foreign organizations and regional organizations.
Are minority-serving institutions specifically included?
Yes. The FOA explicitly includes historically black colleges and universities, Hispanic-serving institutions, tribally controlled colleges and universities, Alaska Native and Native Hawaiian serving institutions, and other related entities.
Are tribal governments and tribal organizations eligible?
Yes. The eligibility section explicitly includes federally recognized and other tribal governments and organizations.
Are faith-based or community-based organizations eligible?
Yes. The FOA explicitly includes faith-based or community-based organizations.
Are U.S. territories eligible?
Yes. The eligibility section explicitly includes U.S. territories or possessions.
Is cost-sharing or matching required?
No. The FOA states there is no cost-sharing or matching requirement.
When was the opportunity posted?
The opportunity was posted on August 17, 2010.
What was the application deadline?
The application deadline was October 14, 2010.
What is the archive date?
The archive date was November 14, 2010.
Which agency administers this FOA?
The administering agency is the National Institutes of Health (NIH).
What research areas does this FOA connect to?
The FOA is tied to multiple CFDA program areas spanning environmental health, mental health, aging, cardiovascular and lung diseases, cancer, minority health and disparities, substance use, sleep, and other biomedical and behavioral research domains.
Why is the FOA tied to so many different program areas?
The FOA frames improved, harmonized measures of psychosocial stress as foundational tools that can strengthen research across many health and disease areas, not just within one institute or specialty.
What is the intended impact of better stress measurement?
The FOA expects that stronger measures, paired with bridges between lab and population research, will clarify which components of psychosocial stressors are most relevant to disease processes and will support better cross-study comparability.
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