Opportunity Information: Apply for RFA RM 09 020
Apply for RFA RM 09 020
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Development of New tools for Computational Analysis of Human Microbiome Project Data (R01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.310 Trans NIH Research Support.
- This funding opportunity was created on Dec 3, 2009 and posted on Dec 3, 2009.
- Applicants must submit their applications by Feb 1, 2010. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $2,500,000.00 to eligible and selected applicants.
- Eligible applicants include: County governments Special district governments Native American tribal governments (Federally recognized) State governments Public and State controlled institutions of higher education Public housing authorities/Indian housing authorities Private institutions of higher education City or township governments Small businesses Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) For profit organizations other than small businesses Independent school districts.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:
The NIH grant opportunity titled "Development of New tools for Computational Analysis of Human Microbiome Project Data (R01)" (Funding Opportunity Number RFA-RM-09-020) focused on advancing the computational side of the Human Microbiome Project (HMP). The central goal was to fund research teams that could create new or substantially improved software, algorithms, and analytic methods to help scientists make better sense of HMP datasets. In practical terms, this meant building tools that strengthen how microbiome data are analyzed, interpreted, and validated, so that results drawn from complex sequencing and associated metadata are more reliable, more comparable across studies, and ultimately more useful for biomedical research.
This funding announcement used the NIH Research Project Grant (R01) mechanism, which is typically intended for more mature, well-developed research plans with clear deliverables. The R01 call ran alongside a separate, parallel announcement with the same scientific scope that used the R21 mechanism (RFA-RM-09-021). The intent of running the two mechanisms in parallel was to support both more established tool-development projects (via R01) and potentially higher-risk or earlier-stage exploratory efforts (via R21), while keeping the overall scientific target consistent: better computational approaches for HMP data.
NIH indicated an estimated total of $2.5 million in FY2010 to support awards made under this R01 announcement and the parallel R21 announcement combined. The agency anticipated making roughly 2 to 5 R01 awards, each with a project period of up to 3 years, and 2 to 4 R21 awards. Rather than setting a single rigid budget cap per award in the public summary, NIH stated that budgets would be negotiated in order to optimize the number of meritorious projects that could be supported. As with most federal research announcements, actual awards were contingent on the availability of appropriated funds and on receiving enough high-quality applications to justify making awards.
Eligibility was broad and included many types of organizations that commonly participate in NIH research funding. Eligible applicants listed in the announcement included state, county, city/township, and special district governments; federally recognized tribal governments and other tribal organizations; public and state-controlled institutions of higher education; private institutions of higher education; nonprofits (both 501(c)(3) and non-501(c)(3), excluding higher education where noted); small businesses and other for-profit organizations (including those other than small businesses); independent school districts; public housing authorities/Indian housing authorities; and additional categories such as Alaska Native and Native Hawaiian Serving Institutions, Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), U.S. territories or possessions, and even non-U.S. (foreign) entities and regional organizations. The announcement also explicitly stated there was no cost sharing or matching requirement, which is typical for many NIH research grants and reduces the barrier for applicants who might not have institutional funds to contribute.
Key administrative details place this opportunity firmly in the 2009-2010 funding cycle. The opportunity was posted on December 3, 2009, with an original and current closing date of February 1, 2010, and it was archived on March 4, 2010. It fell under the NIH umbrella and was categorized under the Health funding activity area, with CFDA number 93.310 (Trans-NIH Research Support). For applicants needing the full text, NIH provided an official guide link, and for technical access or linking issues, the notice directed users to contact the NIH Office of Extramural Research (OER) webmaster.
Overall, the program can be summarized as a targeted NIH investment in the computational infrastructure of microbiome science: funding a small number of competitively selected R01 projects (plus a parallel set of R21s) to produce better computational tools that improve the rigor, interpretability, and validation of analyses performed on Human Microbiome Project data.
Frequently Asked Questions (FAQ)
What is the title of this NIH funding opportunity?
The opportunity is titled "Development of New tools for Computational Analysis of Human Microbiome Project Data (R01)."
What is the Funding Opportunity Number (FON)?
The Funding Opportunity Number is RFA-RM-09-020.
What is the main purpose of this grant opportunity?
The central goal is to fund research teams to create new or substantially improved software, algorithms, and analytic methods that help researchers analyze, interpret, and validate Human Microbiome Project (HMP) datasets. The emphasis is on improving the reliability of results, supporting comparability across studies, and increasing the usefulness of HMP data for biomedical research.
What kind of work was NIH looking to support under this announcement?
NIH was looking for tool-development work on the computational side of the Human Microbiome Project, including development of new (or substantially improved) software tools, algorithms, and analytic methods that strengthen microbiome data analysis and validation.
What grant mechanism does this opportunity use?
This announcement uses the NIH Research Project Grant (R01) mechanism.
How does the R01 mechanism fit the goals of this program?
The R01 mechanism is typically used for more mature, well-developed research plans with clear deliverables. In this context, it supported established tool-development projects aimed at producing usable computational advances for HMP data analysis.
Was there a related or parallel funding opportunity?
Yes. NIH ran a parallel announcement with the same scientific scope using the R21 mechanism (RFA-RM-09-021).
Why were the R01 and R21 announcements run in parallel?
The intent was to support both (1) more established tool-development projects via R01 and (2) potentially higher-risk or earlier-stage exploratory efforts via R21, while keeping the scientific target consistent: improving computational approaches for HMP data.
How much total funding did NIH estimate for these awards?
NIH indicated an estimated total of $2.5 million in FY2010 to support awards under this R01 announcement and the parallel R21 announcement combined.
How many R01 awards did NIH anticipate making?
NIH anticipated making roughly 2 to 5 R01 awards under this announcement.
What was the maximum project period for an R01 award under this opportunity?
The project period could be up to 3 years.
How many R21 awards were anticipated under the parallel R21 announcement?
NIH anticipated making roughly 2 to 4 R21 awards under the parallel announcement.
Was there a fixed budget cap per award?
No single rigid budget cap per award was stated in the public summary. Budgets were expected to be negotiated to optimize the number of meritorious projects that could be supported.
Are awards guaranteed if an application is submitted?
No. As with typical federal research announcements, awards were contingent on the availability of appropriated funds and on receiving enough high-quality applications to justify making awards.
Who was eligible to apply?
Eligibility was broad and included many types of organizations, including: state, county, city/township, and special district governments; federally recognized tribal governments and other tribal organizations; public and state-controlled institutions of higher education; private institutions of higher education; nonprofits (501(c)(3) and non-501(c)(3), excluding higher education where noted); small businesses; other for-profit organizations (including those other than small businesses); independent school districts; public housing authorities/Indian housing authorities; Alaska Native and Native Hawaiian Serving Institutions; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Tribally Controlled Colleges and Universities (TCCUs); U.S. territories or possessions; and non-U.S. (foreign) entities and regional organizations.
Are non-U.S. (foreign) organizations allowed to apply?
Yes. The eligibility list explicitly included non-U.S. (foreign) entities and regional organizations.
Is cost sharing or matching required?
No. The announcement explicitly stated there was no cost sharing or matching requirement.
When was the opportunity posted?
The opportunity was posted on December 3, 2009.
What was the application due date?
The original and current closing date was February 1, 2010.
Is this opportunity still open?
No. It was archived on March 4, 2010, and the closing date listed was February 1, 2010.
Which agency offered this funding opportunity?
The opportunity was offered under the NIH umbrella (National Institutes of Health).
What funding activity area does it fall under?
It was categorized under the Health funding activity area.
What is the CFDA number associated with this opportunity?
The CFDA number listed is 93.310 (Trans-NIH Research Support).
Where could applicants find the official full text or guidance?
NIH provided an official guide link for the full text of the announcement.
Who should be contacted for technical access or linking issues related to the announcement?
The notice directed users to contact the NIH Office of Extramural Research (OER) webmaster for technical access or linking issues.
How can this program be summarized in plain terms?
It was a targeted NIH investment in the computational infrastructure of microbiome science, funding a small number of competitively selected R01 projects (alongside a parallel set of R21s) to produce better computational tools that improve the rigor, interpretability, and validation of analyses performed on Human Microbiome Project data.
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