Opportunity Information: Apply for W81XWH 12 DMRDP MID CTA

  • The Dept. of the Army USAMRAA in the science and technology and other research and development sector is offering a public funding opportunity titled "DHP Defense Medical Research and Development Military Infectious Diseases Clinical Trial Award" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 12.420 Military Medical Research and Development.
  • This funding opportunity was created on Jun 9, 2011 and posted on May 20, 2011.
  • Applicants must submit their applications by Sep 7, 2011. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $10,500,000.00 to eligible and selected applicants.
  • The number of recipients for this funding is limited to 4 candidate(s).
  • Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification).
  • Independent investigators at any academic level (or equivalent) are eligible to submit applications.
Apply for W81XWH 12 DMRDP MID CTA

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Opportunity Summary:

The DHP Defense Medical Research and Development Military Infectious Diseases Clinical Trial Award (MID CTA) is a U.S. Department of Defense funding opportunity run under the Defense Health Program and administered through the U.S. Army Medical Research Acquisition Activity (USAMRAA). It is designed to pay for clinical trials that directly address infectious disease problems tied to combat and military operations, with a clear emphasis on practical, patient-focused studies rather than early-stage lab research. The main scientific priorities highlighted in the announcement are wound infection prevention and management and antimicrobial countermeasures, reflecting the ongoing challenge of infection in battlefield injuries and the need for better ways to prevent, diagnose, and treat these infections in deployed or resource-limited settings.

This opportunity was released as a discretionary, science-and-technology research and development program announcement (Funding Opportunity Number W81XWH-12-DMRDP-MID-CTA; CFDA 12.420 Military Medical Research and Development). The government anticipated making about four awards, supported by an estimated total funding pool of $10.5 million. Cost sharing or matching funds were not required, which generally lowers barriers for applicants and allows proposals to be judged more on scientific and operational merit than on an applicant's ability to bring outside funds.

Eligibility was broad on the investigator side. Independent investigators at any academic level (or an equivalent professional level) were eligible to apply, with the listing indicating that additional eligibility details were provided in the full announcement. In practice, awards of this type typically expect applicants to show they can actually run a clinical trial, which often means having appropriate institutional support, access to the relevant patient populations, regulatory and ethics review capacity, and the operational infrastructure needed for trial management, data collection, safety monitoring, and analysis. The intent is to fund studies that can generate real clinical evidence for interventions that matter to military medicine, particularly in the context of trauma-related infections and antimicrobial resistance risks.

Key dates in the posting show it was published May 20, 2011, with a closing date of September 7, 2011, and later archived on October 7, 2011. For applicants needing assistance accessing the full announcement, the contact listed was the Congressionally Directed Medical Research Programs (CDMRP) helpdesk (301-682-5507, help@cdmrp.org), and the opportunity referenced the USAMRAA website for supporting information.

Frequently Asked Questions (FAQs)

What is the DHP Defense Medical Research and Development Military Infectious Diseases Clinical Trial Award (MID CTA)?

The MID CTA is a U.S. Department of Defense funding opportunity under the Defense Health Program. It is administered through the U.S. Army Medical Research Acquisition Activity (USAMRAA) and is intended to fund clinical trials focused on infectious disease problems associated with combat and military operations.

Who runs and administers this grant program?

The opportunity is run under the Defense Health Program (DHP) and administered through USAMRAA (U.S. Army Medical Research Acquisition Activity).

What types of projects does this award support?

This award is designed to pay for clinical trials that directly address infectious disease problems tied to combat and military operations. The emphasis is on practical, patient-focused clinical studies rather than early-stage laboratory research.

Is this funding meant for laboratory or early-stage research?

No. The announcement emphasizes practical, patient-focused clinical trials rather than early-stage lab research.

What scientific areas are prioritized in this announcement?

The main scientific priorities highlighted are wound infection prevention and management, and antimicrobial countermeasures. These priorities reflect the ongoing challenge of infection in battlefield injuries and the need for improved prevention, diagnosis, and treatment approaches, including in deployed or resource-limited settings.

Why does the announcement focus on wound infections and antimicrobial countermeasures?

The announcement links these priorities to persistent infection risks in battlefield injuries and the need for better ways to prevent, diagnose, and treat infections during military operations, including in environments where resources may be limited.

What is the Funding Opportunity Number for this program?

The Funding Opportunity Number listed is W81XWH-12-DMRDP-MID-CTA.

What CFDA number is associated with this opportunity?

The CFDA number provided is 12.420, Military Medical Research and Development.

What kind of announcement is this (mechanism/type of solicitation)?

It was released as a discretionary, science-and-technology research and development program announcement.

How many awards did the government expect to make?

The government anticipated making about four awards.

How much total funding was estimated for this opportunity?

The estimated total funding pool was $10.5 million.

Is cost sharing or matching required?

No. The announcement states that cost sharing or matching funds were not required.

Who is eligible to apply?

Eligibility was broad on the investigator side. Independent investigators at any academic level (or an equivalent professional level) were eligible to apply, with additional eligibility details referenced as being in the full announcement.

Does the opportunity indicate any practical expectations for running the proposed work?

While the posting emphasizes eligibility by investigator level, it notes that awards of this type typically expect applicants to demonstrate they can actually run a clinical trial. That generally implies access to appropriate patient populations, institutional support, regulatory and ethics review capacity, and the operational infrastructure needed for trial management, data collection, safety monitoring, and analysis.

What is the main intent of funding these clinical trials?

The intent is to fund studies that generate real clinical evidence for interventions that matter to military medicine, particularly in the context of trauma-related infections and antimicrobial resistance risks.

When was this opportunity published?

The posting shows a publication date of May 20, 2011.

What was the application closing date?

The closing date listed was September 7, 2011.

When was the opportunity archived?

The opportunity was archived on October 7, 2011.

Where could applicants find supporting information?

The opportunity referenced the USAMRAA website for supporting information.

Who should be contacted for help accessing the full announcement?

The contact listed for assistance accessing the full announcement was the Congressionally Directed Medical Research Programs (CDMRP) helpdesk at 301-682-5507 or help@cdmrp.org.

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