Opportunity Information: Apply for RFA DK 12 021
Apply for RFA DK 12 021
- The National Institutes of Health in the food and nutrition health sector is offering a public funding opportunity titled "Diabetes Impact Award Closed Loop Technologies Development and Integration of Novel Components for an Automated Artificial Pancreas System (DP3)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.847 Diabetes, Digestive, and Kidney Diseases Extramural Research.
- This funding opportunity was created on Dec 12, 2012 and posted on Dec 12, 2012.
- Applicants must submit their applications by Mar 28, 2013. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) Public housing authorities/Indian housing authorities Independent school districts State governments Special district governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education City or township governments Private institutions of higher education Native American tribal governments (Federally recognized) Small businesses For profit organizations other than small businesses Others (see text field entitled Additional Information on Eligibility for clarification) County governments Public and State controlled institutions of higher education.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
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Opportunity Summary:
The Diabetes Impact Award: Closed Loop Technologies Development and Integration of Novel Components for an Automated Artificial Pancreas System (DP3) (Funding Opportunity Number RFA-DK-12-021) was a discretionary NIH grant opportunity run through the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). Its purpose was to fund original, technology-focused research aimed at improving automated "closed loop" glucose control for people living with Type 1 diabetes. In practical terms, the announcement was looking for projects that could move the field closer to a wearable, portable artificial pancreas system by creating and advancing new components or technologies that could realistically be integrated into a fully automated system that senses glucose and adjusts insulin (and potentially other hormones) delivery in a way that better mimics normal physiology.
This opportunity used the DP3 Research Project Grant mechanism under the NIH Diabetes Impact Award concept. The emphasis was on development and integration of novel components, meaning applicants were expected to do more than basic exploratory research. Competitive projects would generally be those that proposed a clear technological innovation, showed how it could fit into a closed loop architecture, and addressed real-world constraints that matter for an on-body system, such as wearability, portability, automation, reliability, and safety. The overall goal was physiological glucose control, which implies improved performance across everyday conditions that challenge current diabetes management, including meals, exercise, sleep, and day-to-day variability, while reducing risks like hypoglycemia.
The FOA fell under the NIH activity area tied to diabetes and related diseases (CFDA 93.847: Diabetes, Digestive, and Kidney Diseases Extramural Research) and was categorized in the broader health and food/nutrition activity category. The announcement did not require cost sharing or matching, which is typical for many NIH research grants and helps lower the barrier to participation for research organizations.
Eligibility was broad and included many common NIH applicant types: public and private institutions of higher education, nonprofits (including 501(c)(3) and other nonprofit structures), state, county, city/township, and special district governments, independent school districts, public housing authorities/Indian housing authorities, tribal organizations and tribal governments (including federally recognized tribes), and a range of other eligible entities described by NIH. The FOA also allowed applications from small businesses and other for-profit organizations (with the caveat that it specified "for-profit organizations other than small businesses" as eligible as well). Importantly, non-U.S. entities were eligible to apply, including foreign organizations and foreign institutions, and foreign components of U.S. organizations were allowed consistent with NIH policy. The eligibility list also explicitly included a variety of institution types such as HBCUs, Hispanic-serving institutions, tribally controlled colleges and universities, Alaska Native and Native Hawaiian serving institutions, and AANAPISISs, along with faith-based and community-based organizations and eligible federal agencies, reflecting NIH's inclusive eligibility framework.
From an administrative standpoint, the FOA was posted and created on December 12, 2012, and it originally closed on March 28, 2013 (with the same current closing date listed), and it was archived on April 28, 2013. That timeline indicates it was a single-cycle or time-limited call rather than an open-ended program announcement. The sponsoring agency was the National Institutes of Health, specifically NIDDK, and the official funding announcement was hosted on the NIH grants site. For access or technical issues with the electronic announcement, the contact route provided was the NIH Office of Extramural Research (OER) webmaster email.
Overall, the opportunity was essentially a targeted push by NIDDK to accelerate the next generation of artificial pancreas technology by supporting projects that could deliver new, integratable innovations for closed loop diabetes control, with an emphasis on real-world usability and the technical steps needed to translate components into a wearable automated system for people with Type 1 diabetes.
FAQs: Diabetes Impact Award (DP3) Closed Loop Technologies for an Automated Artificial Pancreas System (RFA-DK-12-021)
What is this funding opportunity?
This opportunity was an NIH discretionary funding announcement titled "The Diabetes Impact Award: Closed Loop Technologies Development and Integration of Novel Components for an Automated Artificial Pancreas System (DP3)." The Funding Opportunity Number was RFA-DK-12-021, and it was run through the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK).
What was the purpose of RFA-DK-12-021?
The purpose was to fund original, technology-focused research aimed at improving automated "closed loop" glucose control for people living with Type 1 diabetes. In practical terms, it sought projects that would move the field closer to a wearable, portable artificial pancreas by creating and advancing components or technologies that could realistically be integrated into a fully automated system.
What is meant by "closed loop" glucose control in this announcement?
In this context, "closed loop" refers to an automated system that senses glucose and adjusts insulin delivery (and potentially other hormones) based on that sensed glucose, with the goal of better mimicking normal physiology.
What type of work was the announcement focused on: basic research or development?
The emphasis was on development and integration of novel components rather than basic exploratory research. Applicants were generally expected to propose a clear technological innovation and show how it could fit into a closed loop architecture intended for real-world use.
What does "development and integration of novel components" imply for applicants?
It implies that proposed work should go beyond early-stage exploration and instead focus on creating and advancing new components or technologies and demonstrating how they could be integrated into a wearable, automated closed loop system. Competitive projects would typically explain the integration path and address practical constraints relevant to on-body systems.
What is the grant mechanism used for this opportunity?
This opportunity used the DP3 Research Project Grant mechanism under the NIH Diabetes Impact Award concept.
What end goal was NIDDK trying to accelerate with this FOA?
The overall goal was improved physiological glucose control via next-generation artificial pancreas technology, with an emphasis on innovations that support wearability, portability, automation, reliability, and safety in an on-body system for people with Type 1 diabetes.
What real-world challenges was the FOA trying to address?
The announcement highlighted everyday conditions that challenge diabetes management, including meals, exercise, sleep, and day-to-day variability. It also emphasized reducing risks such as hypoglycemia.
Who was the sponsoring agency for this grant opportunity?
The sponsoring agency was the National Institutes of Health (NIH), specifically the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK).
What CFDA program area was associated with this opportunity?
The opportunity fell under CFDA 93.847: Diabetes, Digestive, and Kidney Diseases Extramural Research.
How was the opportunity categorized in broader activity areas?
It was categorized within the broader health and food/nutrition activity category.
Was cost sharing or matching required?
No. The announcement did not require cost sharing or matching.
What types of organizations were eligible to apply?
Eligibility was broad and included public and private institutions of higher education; nonprofits (including 501(c)(3) and other nonprofit structures); state, county, city/township, and special district governments; independent school districts; public housing authorities/Indian housing authorities; tribal organizations and tribal governments (including federally recognized tribes); and other eligible entities described by NIH.
Were small businesses and for-profit organizations eligible?
Yes. The eligibility description allowed applications from small businesses and also indicated that for-profit organizations other than small businesses were eligible as well.
Could non-U.S. (foreign) organizations apply?
Yes. Non-U.S. entities were eligible to apply, including foreign organizations and foreign institutions. In addition, foreign components of U.S. organizations were allowed consistent with NIH policy.
Did the eligibility list include specific institution types such as minority-serving institutions?
Yes. The eligibility list explicitly included a variety of institution types such as HBCUs, Hispanic-serving institutions, tribally controlled colleges and universities, Alaska Native and Native Hawaiian serving institutions, and AANAPISISs. It also included faith-based and community-based organizations and eligible federal agencies.
When was the FOA posted and when did it close?
The FOA was posted and created on December 12, 2012. It originally closed on March 28, 2013 (with that same date listed as the current closing date in the provided description). It was archived on April 28, 2013.
Is this funding opportunity still open?
No. Based on the provided timeline (closed March 28, 2013 and archived April 28, 2013), this was a time-limited call and is not currently open.
Where was the official announcement hosted?
The official funding announcement was hosted on the NIH grants site.
Who was the contact for access or technical issues with the electronic announcement?
For access or technical issues with the electronic announcement, the contact route provided was the NIH Office of Extramural Research (OER) webmaster email.
What kinds of system constraints were emphasized for proposed technologies?
The announcement emphasized constraints that matter for an on-body system, including wearability, portability, automation, reliability, and safety.
Did the FOA anticipate systems using only insulin, or potentially other hormones too?
It explicitly referenced systems that adjust insulin and noted the potential for delivery of other hormones as well.
What would a competitive project generally be expected to demonstrate, based on the description provided?
Based on the description provided, competitive projects would generally be expected to propose a clear technological innovation, explain how it could fit into a closed loop architecture, and address practical real-world constraints and usability factors relevant to a wearable automated system.
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