Opportunity Information: Apply for RFA HD 12 205
Apply for RFA HD 12 205
- The National Institutes of Health in the health income security and social services sector is offering a public funding opportunity titled "Disclosure of HIV Status to Children in Low and Middle Income Country Settings (R21)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.865 Child Health and Human Development Extramural Research.
- This funding opportunity was created on Feb 9, 2011 and posted on Feb 9, 2011.
- Applicants must submit their applications by Nov 29, 2011. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $500,000.00 to eligible and selected applicants.
- Each selected applicant is eligible to receive up to $250,000.00 in funding.
- Eligible applicants include: Native American tribal organizations (other than Federally recognized tribal governments) For profit organizations other than small businesses Native American tribal governments (Federally recognized) State governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Independent school districts Public housing authorities/Indian housing authorities Small businesses City or township governments Private institutions of higher education Special district governments County governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Public and State controlled institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification).
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:
The NIH Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) offered this R21 grant opportunity to support exploratory, early-stage research on how HIV status is disclosed to children in low- and middle-income country (LMIC) settings. The focus is on pediatric HIV disclosure in low-resource contexts, including situations where a child living with HIV is told about their own diagnosis, as well as situations where an HIV-positive parent, caregiver, or other responsible adult discloses their HIV status to a child. In this announcement, "disclosure" is used broadly to cover any of these disclosure processes, and "adult" is defined broadly to include any caretaker responsible for the child or children.
The core purpose of the funding is to improve understanding of what actually happens around disclosure in real-world settings and what factors influence whether disclosure occurs, how it occurs, and what consequences follow. NICHD specifically solicits exploratory and observational studies that can map out predictors and patterns of disclosure, identify barriers that prevent caregivers and families from disclosing, and capture perceptions and attitudes held by children, caregivers, and families. The opportunity encourages investigators to examine the approaches that are currently being used in LMIC programs and communities, rather than assuming that high-income country models automatically translate to low-resource environments.
Applicants are encouraged to use practical, context-appropriate research methods such as analyses of existing program data, structured questionnaires, in-depth interviews, focus groups, and other suitable qualitative or mixed-method approaches. The intent is to generate actionable evidence about disclosure practices and decision-making. Studies can look at individual-level factors (for example caregiver fears, stigma, beliefs about child readiness, or concerns about confidentiality), family dynamics (such as communication patterns and household stability), and broader social or health-system conditions (including clinic counseling capacity, community stigma, cultural norms, and service integration).
A major area of interest is what happens after disclosure, especially the psychological, behavioral, and medical effects for both the child and the family unit. The FOA highlights both observed and self-reported outcomes, suggesting a strong interest in documenting impacts that may include mental health responses, family relationship changes, adherence to antiretroviral therapy, engagement in clinical care, and changes in risk-related behavior as children mature. The ultimate goal of collecting these outcomes data is not only descriptive; it is meant to help inform the design of disclosure intervention models that can later be tested more rigorously and implemented in the same or similar LMIC settings.
Beyond observational work, the announcement also encourages the development or adaptation of interventions that help families disclose in ways that are appropriate for the setting. This could include creating or tailoring counseling tools, caregiver support approaches, clinic-based protocols, or community-linked strategies that make disclosure safer and more effective. The R21 mechanism signals that NICHD expects pilot-style work: formative research, early feasibility and acceptability testing, and foundational data that can support future, larger studies and implementation efforts.
From an administrative standpoint, this was a discretionary grant opportunity (Funding Opportunity Number RFA-HD-12-205) under CFDA 93.865 (Child Health and Human Development Extramural Research). It was posted February 9, 2011, with an original and final application due date of November 29, 2011, and it was later archived on December 30, 2011. The estimated total funding listed was $500,000, with an award ceiling of $250,000 per award, and it explicitly stated that there was no cost-sharing or matching requirement.
Eligibility was broad and included many types of U.S.-based and non-U.S. organizations. Eligible applicants included state and local governments, tribal governments and tribal organizations, public and private institutions of higher education, nonprofit organizations (including those with and without 501(c)(3) status), for-profit organizations (including small businesses), independent school districts, public housing authorities/Indian housing authorities, and other specialized entities. The eligibility section also explicitly mentioned a range of institution types and community-linked organizations, including faith-based and community-based organizations, foreign organizations (non-U.S. entities), U.S. territories or possessions, regional organizations, Alaska Native and Native Hawaiian Serving Institutions, Hispanic-serving institutions, Historically Black Colleges and Universities (HBCUs), and Tribally Controlled Colleges and Universities (TCCUs). This breadth fits the topic area, since disclosure research often depends on partnerships among clinics, community organizations, and local or regional research institutions in LMIC contexts.
Overall, the opportunity was designed to move the field beyond general statements that disclosure is "important" by funding studies that describe what disclosure looks like on the ground in LMICs, what stands in the way, what helps, and what the short- and longer-term effects are for children and families. The practical end point NICHD is pushing toward is evidence-informed disclosure models and support interventions that can be evaluated further and, if effective, implemented within low-resource health and community systems.
Frequently Asked Questions (FAQs)
What is this funding opportunity?
This is an NIH NICHD R21 discretionary grant opportunity (Funding Opportunity Number RFA-HD-12-205) supporting exploratory, early-stage research on how HIV status is disclosed to children in low- and middle-income country (LMIC) settings.
Which NIH institute is offering this opportunity?
The Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), part of the National Institutes of Health (NIH).
What topic area is the FOA focused on?
The FOA focuses on pediatric HIV disclosure in low-resource contexts, including (1) disclosure to a child living with HIV about their own diagnosis and (2) disclosure to a child about an HIV-positive parent/caregiver/adult's status.
How does this FOA define "disclosure"?
"Disclosure" is used broadly to cover multiple disclosure processes, including telling a child living with HIV about their diagnosis and situations where an adult discloses their own HIV status to a child.
Who is considered an "adult" for purposes of this FOA?
"Adult" is defined broadly to include any caretaker responsible for the child or children, not only biological parents.
What is the main purpose of the funding?
The purpose is to improve understanding of what happens around disclosure in real-world LMIC settings, what factors influence whether disclosure occurs and how it occurs, and what consequences follow for children and families.
What kinds of studies are specifically solicited?
NICHD specifically solicits exploratory and observational studies that map predictors and patterns of disclosure, identify barriers to disclosure, and capture perceptions and attitudes held by children, caregivers, and families.
Does the FOA encourage relying on high-income country disclosure models?
No. The FOA encourages investigators to examine the approaches currently being used in LMIC programs and communities, rather than assuming high-income country models automatically translate to low-resource environments.
What research methods are encouraged?
The FOA encourages practical, context-appropriate methods such as analyses of existing program data, structured questionnaires, in-depth interviews, focus groups, and other suitable qualitative or mixed-method approaches.
Can researchers use existing program or clinic data?
Yes. Analyses of existing program data are explicitly listed as an encouraged approach.
What factors related to disclosure decision-making can be studied?
Studies can examine individual-level factors (for example caregiver fears, stigma, beliefs about child readiness, confidentiality concerns), family dynamics (communication patterns, household stability), and broader social or health-system conditions (clinic counseling capacity, community stigma, cultural norms, service integration).
What is NICHD looking for regarding barriers to disclosure?
The FOA highlights the need to identify barriers that prevent caregivers and families from disclosing, in order to better understand what stands in the way and what might help disclosure occur in safer, more effective ways.
What outcomes after disclosure are of interest?
A major area of interest is what happens after disclosure, including psychological, behavioral, and medical effects for both the child and the family unit, using observed and/or self-reported outcomes.
What are examples of post-disclosure outcomes mentioned in the FOA?
Examples include mental health responses, family relationship changes, adherence to antiretroviral therapy, engagement in clinical care, and changes in risk-related behavior as children mature.
Is the FOA only descriptive, or does it also aim to inform future intervention design?
While the FOA supports descriptive and observational work, it explicitly frames outcomes data as a way to inform the design of disclosure intervention models that can later be tested more rigorously and implemented in LMIC settings.
Does this opportunity support intervention development?
Yes. Beyond observational work, the FOA encourages the development or adaptation of interventions that help families disclose in ways that are appropriate for the setting.
What types of interventions might fit within the FOA scope?
Examples mentioned include creating or tailoring counseling tools, caregiver support approaches, clinic-based protocols, or community-linked strategies aimed at making disclosure safer and more effective.
What does the R21 mechanism imply about the stage and scale of work?
The R21 mechanism signals pilot-style work, such as formative research, early feasibility and acceptability testing, and generating foundational data to support future larger studies and implementation efforts.
What is the Funding Opportunity Number?
RFA-HD-12-205.
What is the CFDA number listed for this opportunity?
CFDA 93.865 (Child Health and Human Development Extramural Research).
When was the opportunity posted and when was it due?
It was posted on February 9, 2011. The original and final application due date was November 29, 2011.
Is this funding opportunity still active?
No. The opportunity was archived on December 30, 2011.
How much total funding was estimated for this FOA?
The estimated total funding listed was $500,000.
What was the maximum award amount (award ceiling) per award?
The award ceiling was $250,000 per award.
Is cost-sharing or matching required?
No. The FOA explicitly stated there was no cost-sharing or matching requirement.
Who was eligible to apply?
Eligibility was broad and included many U.S.-based and non-U.S. organizations, including governments, tribal entities, higher education institutions, nonprofits, for-profits (including small businesses), and other specialized entities.
Are foreign (non-U.S.) organizations eligible?
Yes. Foreign organizations (non-U.S. entities) were explicitly listed as eligible.
Are community-based and faith-based organizations eligible?
Yes. The eligibility language explicitly mentions community-linked organizations, including faith-based and community-based organizations.
Are U.S. territories or possessions eligible?
Yes. U.S. territories or possessions were explicitly included in the eligibility description.
Are for-profit organizations eligible?
Yes. For-profit organizations (including small businesses) were listed as eligible applicants.
Are institutions serving specific populations explicitly included in eligibility?
Yes. The eligibility section explicitly mentioned Alaska Native and Native Hawaiian Serving Institutions, Hispanic-serving institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), and other related institution types.
What kinds of partnerships does the FOA seem to anticipate?
Because disclosure research in LMIC contexts often depends on relationships among clinics, community organizations, and local or regional research institutions, the FOA's broad eligibility aligns with partnership-based approaches across health and community systems.
What is the practical endpoint NICHD is pushing toward?
The FOA aims to move the field beyond general statements that disclosure is "important" by supporting evidence that describes real-world disclosure practices, barriers and facilitators, and short- and longer-term effects, ultimately informing evidence-informed disclosure models and support interventions suitable for low-resource systems.
Browse more opportunities from the same category: Health Income Security and Social Services
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Previous opportunity: Supporting Indigenous Organizations to Implement and Expand Comprehensive HIV/AIDS Prevention, Care and Treatment in the Republic of Mozambique under the President s Emergency Plan for AIDS Relief (PEPFAR)
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