Dissemination and Implementation Research in Health (R01) | Apply Online

Opportunity Summary:

The NIH grant opportunity "Dissemination and Implementation Research in Health (R01)" (Funding Opportunity Number PAR-10-038) supports research aimed at closing the gap between what is known to work in health and what is routinely done in real-world public health and clinical settings. The central focus is on dissemination and implementation (D and I) research: studies that identify, develop, test, and refine practical methods, organizational structures, and strategies that help proven interventions and evidence-based services get adopted, integrated, and sustained in everyday practice. Rather than inventing brand-new clinical discoveries, the emphasis is on improving how research-tested health behavior change interventions and evidence-based approaches to prevention, early detection, diagnosis, treatment, and quality-of-life improvement are actually delivered at scale, with attention to effectiveness, efficiency, and fit within real systems.

This FOA uses the NIH Research Project Grant (R01) mechanism, which is typically suited for more mature, hypothesis-driven projects with a well-developed research plan, larger scope, and stronger evidence base than early-stage exploratory work. It is explicitly linked to companion announcements with the same scientific scope that use smaller mechanisms: PAR-10-039 (R03) for small, focused projects and PAR-10-040 (R21) for exploratory or developmental studies. In practical terms, this means applicants should view PAR-10-038 as the R01 pathway for more substantial D and I studies that may involve complex designs, multi-site implementation, comparative strategy testing, rigorous measurement of implementation processes and outcomes, and evaluation of sustainability in routine care or public health systems.

Funding levels and the number of awards are not fixed because project needs can vary widely in D and I research. NIH indicates that both the size and duration of awards will depend on the proposed research, and that total funding and award counts will ultimately be driven by the mix of mechanisms, the number of applications submitted, and the scientific merit, duration, and budgets of those applications. The FOA states there is no cost sharing or matching requirement, which reduces financial barriers for applicants and keeps the focus on the strength and feasibility of the research plan.

The announcement is broad in terms of eligible applicant organizations, reflecting the applied, real-world nature of dissemination and implementation science. Eligible applicants include many types of public entities (state, county, city or township governments; special district governments), education-related organizations (independent school districts; public and state-controlled institutions of higher education; private institutions of higher education), housing authorities, and a wide range of nonprofit and for-profit organizations (including nonprofits with or without 501(c)(3) status, small businesses, and other for-profit organizations). It also explicitly includes tribal governments (federally recognized) and other tribal organizations, as well as institutions and organizations serving specific communities, such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, faith-based or community-based organizations, regional organizations, and U.S. territories or possessions. Importantly, the eligibility list also allows non-U.S. entities (foreign organizations), signaling openness to international dissemination and implementation research where relevant and scientifically justified.

From a topical perspective, the FOA aligns with multiple health and disease areas reflected in its CFDA numbers, including cancer prevention, cardiovascular diseases, infectious diseases, allergy and immunology, nursing research, oral health, mental health, alcohol, drug abuse and addiction, and communication disorders related to deafness. This breadth is a reminder that D and I research is not confined to one clinical domain; it is about the methods and strategies that help evidence-based practices become routine across many conditions, settings, and populations.

Administratively, the opportunity was posted and created on November 30, 2009, with an original and current closing date of January 7, 2013, and an archive date of February 7, 2013. That means this specific FOA is historical and no longer open for submission, but it remains useful as a description of NIH priorities and the structure of D and I funding during that period, and it points to the NIH Grants Guide page as the authoritative source. The sponsoring agency is the National Institutes of Health, and the listing provides NIH Office of Extramural Research (OER) contact information for access or linking issues related to the full announcement.

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