Opportunity Information: Apply for CDC RFA GH12 1248

  • The Centers for Disease Control and Prevention in the health sector is offering a public funding opportunity titled "District Health System Strengthening and Quality Improvement for Service Delivery in Malawi under the Presidents Emergency Plan for AIDS Relief (PEPFAR)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.067 Global AIDS.
  • This funding opportunity was created on Mar 23, 2012 and posted on Jan 24, 2012.
  • Applicants must submit their applications by Apr 9, 2012. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $46,000,000.00 to eligible and selected applicants.
  • Each selected applicant is eligible to receive up to $6,000,000.00 in funding.
  • The number of recipients for this funding is limited to 3 candidate(s).
  • Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification) Native American tribal governments (Federally recognized) For profit organizations other than small businesses County governments Independent school districts Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education City or township governments Private institutions of higher education Special district governments Public and State controlled institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses State governments.
  • Eligibile applicants include Nonprofit with 501C3 IRS status (other than institution of higher education), Nonprofit without 501C3 IRS status (other than institution of higher education), For profit organizations (other than small business), Small, minority, and women owned businesses, Universities, Colleges, Research institutions, Hospitals, Community based organizations, Faith based organizations, Federally recognized or state recognized American Indian/Alaska Native tribal governments, American Indian/Alaska native tribally designated organizations, Alaska Native health corporations, Urban Indian health organizations, Tribal epidemiology centers, State and local governments or their Bona Fide Agents (this includes the District of Columbia, the Commonwealth of Puerto Rico, the Virgin Islands, the Commonwealth of the Northern Marianna Islands, American Samoa, Guam, the Federated States of Micronesia, the Republic of the Marshall Islands, and the Republic of Palau), Political subdivisions of States (in consultation with States), Non domestic (non U.S.) entity. A Bona Fide Agent is an agency/organization identified by the state as eligible to submit an application under the state eligibility in lieu of a state application. If applying as a bona fide agent of a state or local government, a legal, binding agreement from the state or local government as documentation of the status is required. Attach with Other Attachment Forms when submitting via www.grants.gov.
Apply for CDC RFA GH12 1248

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Opportunity Summary:

The District Health System Strengthening and Quality Improvement for Service Delivery in Malawi grant opportunity is a CDC-funded PEPFAR cooperative agreement focused on lowering illness and deaths across the population in selected Malawian districts, with particular attention to HIV and tuberculosis, prevention of mother-to-child transmission of HIV, and maternal and child health. The central idea is that better health outcomes will come not only from delivering services at clinics and hospitals, but also from improving how districts plan, budget, manage, and implement health programs. The opportunity emphasizes that district health systems are not static, so effective support must be flexible and tailored to local context, while also building the ability of district teams to keep improvements going over time and to expand what works.

Programmatically, the opportunity targets two interconnected levels of the health system. At the district management level, it aims to strengthen district-based planning and budgeting processes so that decisions are more effective, sustainable, equitable, and efficient. In practice, this means helping district leadership and management teams use better data and more disciplined planning to choose priorities, allocate resources, coordinate partners, and track performance. At the facility level, the program supports evidence-based prevention, care, and treatment interventions, meaning activities are expected to align with proven approaches for HIV and TB service delivery, maternal and child health, and PMTCT, rather than relying on ad hoc or untested models. A key feature of the approach is empowering local management teams to adapt implementation strategies as conditions change, which is important in settings where staffing, supply chains, patient volume, and epidemiology can shift quickly.

Capacity building is a core method rather than a side component. The announcement highlights mentorship and coaching in both clinical practice and health systems management. Clinically, this typically involves improving the quality and consistency of care through on-site mentoring, supportive supervision, and problem-solving with providers. On the systems side, it implies strengthening management routines such as performance monitoring, quality improvement processes, data use for decision-making, and operational planning. The overall intent is to build durable district and facility capability so that improvements in service delivery and outcomes can be maintained after the period of intensive external support, which aligns with PEPFAR priorities around sustainability and health system resilience.

From an administrative and funding standpoint, this opportunity (Funding Opportunity Number CDC RFA GH12-1248) is categorized as discretionary funding and uses a cooperative agreement mechanism, which generally means CDC expects substantial involvement in guiding or partnering on program implementation compared with a standard grant. The activity category is health, and the CFDA number listed is 93.067 (Global AIDS). The estimated total funding amount is $46,000,000, with an expected three awards. Individual awards are described with a ceiling of $6,000,000 and a floor of $250,000. There is no cost sharing or matching requirement, reducing the financial barrier for applicants who may not have significant non-federal funds to contribute.

Eligibility is broad and includes many types of U.S. and non-U.S. entities. Eligible applicants include nonprofits with and without 501(c)(3) status (excluding institutions of higher education in those specific nonprofit categories), for-profit organizations (including small, minority-, and women-owned businesses), universities, colleges, research institutions, hospitals, community-based organizations, and faith-based organizations. Government eligibility also extends to state and local governments and their bona fide agents, as well as political subdivisions of states, and it explicitly includes federally or state-recognized American Indian/Alaska Native tribal governments and related tribal organizations. Non-domestic (non-U.S.) entities are also eligible, which is important for Malawi-based or regionally based implementers. For applicants applying as a bona fide agent of a state or local government, the announcement specifies that a legal, binding agreement documenting that status must be submitted with the application materials.

Key dates show that the opportunity was posted January 24, 2012, created March 23, 2012, and had an original closing date of March 26, 2012, later extended to April 9, 2012, with an archive date of May 9, 2012. The announcement provides a CDC Procurement and Grants Office contact (Technical Information Management Section) for help accessing the full announcement, indicating that the detailed requirements, scoring criteria, and district focus would be contained in the full funding notice rather than in the brief synopsis. Overall, the opportunity can be read as an investment in district-level governance and facility-level quality improvement to strengthen HIV/TB and maternal-child service delivery in Malawi in a way that is data-driven, adaptable, and sustainable.

Frequently Asked Questions (FAQs)

What is the title of this grant opportunity?

The opportunity is titled District Health System Strengthening and Quality Improvement for Service Delivery in Malawi.

Who is funding this opportunity?

This is a CDC-funded opportunity under PEPFAR.

What is the funding mechanism?

The mechanism is a cooperative agreement, which generally indicates that CDC expects to have substantial involvement in guiding or partnering on program implementation compared with a standard grant.

What is the Funding Opportunity Number (FON)?

The Funding Opportunity Number is CDC RFA GH12-1248.

What is the CFDA number and program area?

The CFDA number listed is 93.067 (Global AIDS).

What is the main goal of the program?

The central goal is to reduce illness and deaths across the population in selected Malawian districts, with particular attention to HIV, tuberculosis (TB), prevention of mother-to-child transmission of HIV (PMTCT), and maternal and child health.

What is the core strategy behind this opportunity?

The opportunity emphasizes that stronger health outcomes come not only from providing services at clinics and hospitals, but also from improving district-level planning, budgeting, management, and implementation of health programs. It also highlights the need for approaches that are flexible, tailored to local context, and designed to build the ability of district teams to sustain and scale improvements.

What levels of the health system does the program target?

The program targets two interconnected levels:

  • District management level: Strengthening district-based planning and budgeting and improving how decisions are made and tracked.
  • Facility level: Supporting evidence-based prevention, care, and treatment interventions aligned with proven approaches for HIV, TB, PMTCT, and maternal/child health.

What does "district health systems strengthening" mean in this opportunity?

Based on the synopsis, it means improving how districts use data and structured processes to set priorities, allocate resources, coordinate partners, and monitor performance, with an emphasis on decisions being more effective, sustainable, equitable, and efficient.

What does "quality improvement for service delivery" refer to here?

It refers to strengthening the quality and consistency of services at the facility level, including through mentorship, coaching, supportive supervision, problem-solving with providers, and stronger routines for performance monitoring and continuous improvement.

Which health areas are specifically highlighted?

The synopsis specifically highlights:

  • HIV
  • Tuberculosis (TB)
  • Prevention of mother-to-child transmission of HIV (PMTCT)
  • Maternal and child health

Are applicants expected to use evidence-based interventions?

Yes. The facility-level portion of the opportunity emphasizes evidence-based prevention, care, and treatment interventions, meaning activities are expected to align with proven approaches rather than ad hoc or untested models.

Why does the opportunity emphasize flexibility and local adaptation?

The synopsis notes that district health systems are not static and that implementation conditions can change (for example, staffing, supply chains, patient volume, and epidemiology). The approach therefore emphasizes empowering local management teams to adapt strategies as conditions shift.

Is capacity building a required part of the approach?

Capacity building is described as a core method of the program. The synopsis highlights mentorship and coaching in both clinical practice and health systems management to build durable district and facility capability.

What types of capacity building activities are described?

The synopsis describes capacity building through:

  • Clinical mentorship and coaching: On-site mentoring, supportive supervision, and practical problem-solving with providers to improve care quality and consistency.
  • Health systems management support: Strengthening routines like performance monitoring, quality improvement processes, data use for decision-making, and operational planning.

What is the intent related to sustainability?

The overall intent is to build district and facility capability so improvements can be maintained after intensive external support, aligning with PEPFAR priorities on sustainability and health system resilience.

What is the total estimated funding amount?

The estimated total funding amount is $46,000,000.

How many awards are expected?

The opportunity indicates an expectation of three awards.

What are the minimum and maximum award amounts?

Individual awards are described with a ceiling of $6,000,000 and a floor of $250,000.

Is cost sharing or matching required?

No. The synopsis states there is no cost sharing or matching requirement.

What type of funding is this categorized as?

This opportunity is categorized as discretionary funding.

What is the activity category?

The activity category is listed as health.

Who is eligible to apply?

Eligibility is broad and includes many U.S. and non-U.S. entities. The synopsis lists eligible applicants including:

  • Nonprofits with and without 501(c)(3) status (excluding institutions of higher education in those specific nonprofit categories)
  • For-profit organizations (including small, minority-, and women-owned businesses)
  • Universities, colleges, and research institutions
  • Hospitals
  • Community-based organizations
  • Faith-based organizations
  • State and local governments and their bona fide agents
  • Political subdivisions of states
  • Federally or state-recognized American Indian/Alaska Native tribal governments and related tribal organizations
  • Non-domestic (non-U.S.) entities

Are non-U.S. (non-domestic) organizations eligible?

Yes. The synopsis explicitly states that non-domestic (non-U.S.) entities are eligible, which can include Malawi-based or regionally based implementers.

What is required if applying as a bona fide agent of a state or local government?

The synopsis specifies that applicants applying as a bona fide agent must submit a legal, binding agreement documenting that status with their application materials.

When was the opportunity posted and when did it close?

The key dates listed are:

  • Posted: January 24, 2012
  • Created: March 23, 2012
  • Original closing date: March 26, 2012
  • Extended closing date: April 9, 2012
  • Archive date: May 9, 2012

Is this opportunity still open?

Based on the provided dates (closing in April 2012 and archived in May 2012), the opportunity appears to be closed.

Where is the work intended to take place?

The program focus is on selected districts in Malawi.

Does the synopsis list the specific districts?

No. The synopsis indicates that detailed requirements and the district focus would be contained in the full funding notice rather than the brief summary provided.

How can applicants get help accessing the full announcement?

The synopsis notes a contact within the CDC Procurement and Grants Office (Technical Information Management Section) for assistance accessing the full announcement, where detailed requirements, scoring criteria, and district focus would be provided.

What kinds of program management improvements are encouraged at the district level?

The synopsis highlights improvements such as better data use and disciplined planning to help district teams:

  • Choose priorities
  • Allocate resources
  • Coordinate partners
  • Track performance

How does the cooperative agreement aspect affect implementation expectations?

Because the mechanism is a cooperative agreement, the synopsis indicates CDC is likely to have substantial involvement in guiding or partnering on implementation, rather than acting only as a funder.

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