Opportunity Information: Apply for W81XWH 14 ASARP CA
Apply for W81XWH 14 ASARP CA
- The Dept. of the Army USAMRAA in the science and technology and other research and development sector is offering a public funding opportunity titled "DoD Alcohol and Substance Abuse Consortium Award" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 12.420 Military Medical Research and Development.
- This funding opportunity was created on Jan 22, 2015 and posted on Jan 22, 2015.
- Applicants must submit their applications by Mar 5, 2015. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $10,600,000.00 to eligible and selected applicants.
- The number of recipients for this funding is limited to 1 candidate(s).
- Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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Opportunity Summary:
The DoD Alcohol and Substance Abuse Consortium Award (Funding Opportunity Number W81XWH 14 ASARP CA) is a Department of the Army, USAMRAA-managed funding opportunity designed to create a coordinated, multi-institution research Consortium focused on improving pharmacological treatments for alcohol and substance use disorders (ASUD). Rather than funding a single standalone research project, this award is intended to build an organized network of collaborators who can move promising ideas from basic science into early, proof-of-principle human testing, with a clear plan for eventual clinical implementation.
At the center of the Consortium is a single Management Core that provides leadership, coordination, and overall program direction. Around that core, the Consortium is expected to include multiple basic research sites and clinical trial sites. Together, these groups are meant to function as one integrated team, jointly deciding which candidate compounds or treatment concepts are most promising, designing the studies needed to evaluate them, carrying out both preclinical or mechanistic work and early-stage clinical trials, and then analyzing results to determine which approaches merit further development.
A major emphasis of the award is translation, meaning the work is not limited to generating scientific knowledge in isolation. The Consortium is expected to develop a practical roadmap that links basic science findings to enhanced clinical pharmacological treatment protocols for ASUD. This includes identifying and prioritizing compounds, executing proof-of-principle basic research and proof-of-principle human clinical trials, and outlining the steps needed to progress successful candidates toward broader clinical use. Importantly, the roadmap must also include a regulatory strategy that anticipates FDA compliance requirements, reflecting an expectation that the Consortium will plan for real-world development and not just exploratory research.
The funding mechanism is a cooperative agreement, which typically indicates substantial involvement by the funding agency during the project period, such as programmatic coordination, milestone-driven oversight, or collaboration on priorities. The opportunity falls under the Science and Technology and other Research and Development activity category and is associated with CFDA 12.420 (Military Medical Research and Development). The award did not require cost sharing or matching.
In terms of scale and competitiveness, the opportunity anticipated making a single award, with an estimated total funding level of $10,600,000. Eligibility was listed as unrestricted, meaning it was open to a wide range of applicant entity types, subject to any clarifications in the full announcement. The opportunity was posted on January 22, 2015, with an application closing date of March 5, 2015, and it was later archived on April 4, 2015. For technical issues accessing the announcement, the listed point of contact was the CDMRP Help Desk at 301-682-5507.
Frequently Asked Questions (FAQs)
What is the DoD Alcohol and Substance Abuse Consortium Award?
The DoD Alcohol and Substance Abuse Consortium Award (Funding Opportunity Number W81XWH 14 ASARP CA) is a Department of the Army, USAMRAA-managed funding opportunity intended to establish a coordinated, multi-institution research Consortium focused on improving pharmacological treatments for alcohol and substance use disorders (ASUD).
Is this award meant to fund a single research project?
No. The award is not designed to support one standalone research project. It is intended to build an organized network (a Consortium) that can move promising ideas from basic science into early, proof-of-principle human testing, with a plan for eventual clinical implementation.
What is the main goal of the Consortium?
The Consortium is expected to function as an integrated team that identifies and prioritizes promising candidate compounds or treatment concepts for ASUD, designs and conducts the necessary studies (including basic research and early-stage clinical trials), analyzes results, and determines which approaches should move forward toward broader clinical use.
What kinds of disorders does this opportunity focus on?
The focus is on alcohol and substance use disorders (ASUD), specifically on improving pharmacological treatment options.
What is the expected structure of the Consortium?
The Consortium is centered on a single Management Core that provides leadership, coordination, and overall program direction. Around the Management Core, the Consortium is expected to include multiple basic research sites and clinical trial sites working together as one coordinated program.
What is the Management Core and what does it do?
The Management Core is the central coordinating component of the Consortium. It provides leadership, coordination, and overall program direction for the multi-institution team.
Are both basic research and clinical trials expected under this award?
Yes. The Consortium is expected to include multiple basic research sites and multiple clinical trial sites, supporting both preclinical or mechanistic work and early-stage, proof-of-principle human clinical trials.
What does "translation" mean in the context of this funding opportunity?
Translation is a major emphasis of the award and means the work should connect basic science findings to practical, enhanced clinical pharmacological treatment protocols for ASUD, rather than producing knowledge in isolation.
What is meant by "proof-of-principle" research and testing?
Based on the opportunity description, "proof-of-principle" refers to early studies designed to show whether a compound or treatment concept is promising. This includes proof-of-principle basic research and proof-of-principle human clinical trials.
What is the expected roadmap, and what should it include?
The Consortium is expected to develop a practical roadmap that links basic science findings to enhanced clinical pharmacological treatment protocols for ASUD. The roadmap is described as including identification and prioritization of compounds, execution of proof-of-principle basic research and proof-of-principle human clinical trials, and a plan outlining steps to move successful candidates toward broader clinical use.
Does the roadmap need to address regulatory requirements?
Yes. The roadmap must include a regulatory strategy that anticipates FDA compliance requirements, reflecting an expectation that the Consortium will plan for real-world development and not only exploratory research.
What type of funding mechanism is used for this award?
The funding mechanism is a cooperative agreement.
What does it mean that the mechanism is a cooperative agreement?
A cooperative agreement typically indicates substantial involvement by the funding agency during the project period. The description notes this may include programmatic coordination, milestone-driven oversight, or collaboration on priorities.
Which agency manages this funding opportunity?
The opportunity is managed by the U.S. Army Medical Research Acquisition Activity (USAMRAA) under the Department of the Army.
What is the activity category for this opportunity?
The opportunity falls under the Science and Technology and other Research and Development activity category.
What CFDA number is associated with this opportunity?
The opportunity is associated with CFDA 12.420 (Military Medical Research and Development).
How many awards were expected to be made?
The opportunity anticipated making a single award.
What was the estimated total funding level?
The estimated total funding level was $10,600,000.
Was cost sharing or matching required?
No. The award did not require cost sharing or matching.
Who was eligible to apply?
Eligibility was listed as unrestricted, meaning the opportunity was open to a wide range of applicant entity types, subject to any clarifications in the full announcement.
When was the opportunity posted and when did it close?
The opportunity was posted on January 22, 2015, and the application closing date was March 5, 2015.
Is this funding opportunity still open?
No. The opportunity was later archived on April 4, 2015.
What is the Funding Opportunity Number for this award?
The Funding Opportunity Number is W81XWH 14 ASARP CA.
Who should be contacted for technical issues accessing the announcement?
For technical issues accessing the announcement, the listed point of contact was the CDMRP Help Desk at 301-682-5507.
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