Opportunity Information: Apply for W81XWH 12 ALSRP TIA

  • The Dept. of the Army USAMRAA in the science and technology and other research and development sector is offering a public funding opportunity titled "DoD Amyotrophic Lateral Sclerosis Therapeutic Idea Award" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 12.420 Military Medical Research and Development.
  • This funding opportunity was created on Mar 8, 2012 and posted on Mar 8, 2012.
  • Applicants must submit their applications by Jul 24, 2012. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $640,000.00 to eligible and selected applicants.
  • The number of recipients for this funding is limited to 1 candidate(s).
  • Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
Apply for W81XWH 12 ALSRP TIA

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Opportunity Summary:

The DoD Amyotrophic Lateral Sclerosis (ALS) Therapeutic Idea Award is a U.S. Department of Defense funding opportunity intended to spark new, early-stage therapeutic concepts for treating ALS. The program is built to push the field toward fresh directions by supporting projects that are still in development but have the potential to generate influential data and open up new lines of investigation. A key emphasis is on conceptually innovative work that carries higher risk but also offers the possibility of high reward, meaning the DoD is explicitly looking for ideas that could lead to major breakthroughs or meaningful advances in ALS therapeutics rather than incremental extensions of existing approaches. Proposed research is expected to be grounded in a strong scientific rationale and framed around a clearly defined, testable hypothesis, reinforcing that even early-stage concepts need a coherent experimental plan and logical basis.

Administratively, this opportunity was released by the Department of the Army through the U.S. Army Medical Research Acquisition Activity (USAMRAA) under Funding Opportunity Number W81XWH-12-ALSRP-TIA, with the official title "DoD Amyotrophic Lateral Sclerosis Therapeutic Idea Award." It falls under the category of discretionary funding and supports science and technology research and development activities. Awards could be made through a cooperative agreement or grant mechanism. The estimated total funding available for this announcement was $640,000, and the announcement anticipated making one award. There was no cost sharing or matching requirement, which means applicants were not required to provide non-federal funds to be eligible or competitive.

Eligibility was listed as unrestricted, indicating that any type of entity could apply (such as universities, non-profits, for-profits, or other organizations), subject to any additional eligibility details that may have been included in the full announcement text. The opportunity was posted on March 8, 2012, with an application closing date of July 24, 2012, and it was later archived on August 23, 2012. The associated CFDA number was 12.420 (Military Medical Research and Development), which is the catalog identifier tied to the underlying federal assistance program.

For applicant support, the announcement directed those who had trouble accessing the full posting electronically to contact the Congressionally Directed Medical Research Programs (CDMRP) Help Desk at 301-682-5507 or by email at help@cdmrp.org.

FAQs: DoD Amyotrophic Lateral Sclerosis (ALS) Therapeutic Idea Award

What is the DoD ALS Therapeutic Idea Award?

The DoD Amyotrophic Lateral Sclerosis (ALS) Therapeutic Idea Award is a U.S. Department of Defense funding opportunity intended to spark new, early-stage therapeutic concepts for treating ALS.

What is the main goal of this funding opportunity?

The program is designed to push the ALS therapeutics field in fresh directions by supporting projects that are still in development but could generate influential data and open new lines of investigation.

What type of projects is this award looking to support?

This opportunity emphasizes conceptually innovative therapeutic ideas. It is specifically oriented toward early-stage concepts that may not be fully developed yet, but that have the potential to meaningfully advance ALS therapeutics.

Does the program encourage high-risk, high-reward research?

Yes. A key emphasis is on innovative work that carries higher risk but also offers the possibility of high reward. The DoD is explicitly looking for ideas that could lead to major breakthroughs or meaningful advances, rather than incremental extensions of existing approaches.

Do proposals need a scientific rationale if the work is early-stage?

Yes. Even though the program supports early-stage concepts, proposed research is expected to be grounded in a strong scientific rationale.

Is a hypothesis required?

Yes. The research should be framed around a clearly defined, testable hypothesis.

Does the opportunity expect a coherent experimental plan?

Yes. The description emphasizes that early-stage concepts still need a logical basis and coherent experimental plan tied to the testable hypothesis.

Who released this funding opportunity?

The opportunity was released by the Department of the Army through the U.S. Army Medical Research Acquisition Activity (USAMRAA).

What is the Funding Opportunity Number (FON) for this announcement?

The Funding Opportunity Number listed for this award is W81XWH-12-ALSRP-TIA.

What is the official title of the announcement?

The official title is "DoD Amyotrophic Lateral Sclerosis Therapeutic Idea Award."

What type of funding category does this fall under?

It was categorized as discretionary funding and supports science and technology research and development activities.

What award mechanisms may be used?

Awards could be made through either a cooperative agreement or a grant mechanism.

How much total funding was estimated to be available?

The estimated total funding available for the announcement was $640,000.

How many awards were expected to be made?

The announcement anticipated making one award.

Is cost sharing or matching required?

No. There was no cost sharing or matching requirement, meaning applicants were not required to provide non-federal funds to be eligible or competitive.

Who is eligible to apply?

Eligibility was listed as unrestricted, indicating that any type of entity could apply (for example, universities, non-profits, for-profits, or other organizations), subject to any additional eligibility details that may have been included in the full announcement text.

When was the opportunity posted?

The opportunity was posted on March 8, 2012.

What was the application closing date?

The application closing date was July 24, 2012.

When was the opportunity archived?

The opportunity was archived on August 23, 2012.

What is the CFDA number associated with this opportunity?

The associated CFDA number was 12.420, which corresponds to Military Medical Research and Development.

What should I do if I cannot access the full posting electronically?

The announcement directed applicants who had trouble accessing the full posting electronically to contact the Congressionally Directed Medical Research Programs (CDMRP) Help Desk.

How can I contact the CDMRP Help Desk?

You can contact the CDMRP Help Desk by phone at 301-682-5507 or by email at help@cdmrp.org.

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