Opportunity Information: Apply for W81XWH 10 ARP IDA

  • The Dept. of the Army USAMRAA in the science and technology and other research and development sector is offering a public funding opportunity titled "DoD Autism Idea Development Award" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 12.420 Military Medical Research and Development.
  • This funding opportunity was created on Feb 17, 2010 and posted on Feb 16, 2010.
  • Applicants must submit their applications by Jul 28, 2010. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $3,000,000.00 to eligible and selected applicants.
  • The number of recipients for this funding is limited to 5 candidate(s).
  • Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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Opportunity Summary:

The DoD Autism Idea Development Award (Funding Opportunity Number W81XWH-10-ARP-IDA) is a Department of the Army/USAMRAA funding opportunity under the Autism Research Program (ARP) designed to push forward innovative, high-impact research that deepens the understanding of autism spectrum disorder (ASD) and is positioned to ultimately improve real-world outcomes for individuals with autism. It uses a grant/cooperative agreement structure within the science and technology research and development category, with an estimated total program funding level of about $3,000,000 and an expectation of roughly 5 awards. The opportunity is broadly open to eligible applicants without a cost-sharing or matching requirement.

The central purpose of this award is idea development: supporting projects that introduce genuinely original concepts, tools, or approaches rather than incremental extensions of previously published work. The program makes clear that competitiveness depends heavily on two core review priorities: impact and innovation. Impact means the work should make an important, original contribution to ASD understanding and have a believable path toward improving outcomes. Innovation means the proposed research should bring something meaningfully new, such as a new paradigm, a challenge to prevailing assumptions, a fresh perspective on an existing problem, or a novel method or technology (including creative adaptations of existing methods). Applicants are expected to explicitly spell out what is innovative about the project and why that innovation matters for ASD.

Human subjects research is allowed, but there is a firm restriction: studies must be conducted without clinical trials. The announcement uses a standard definition of a clinical trial as a prospective human study in which an intervention (such as a drug, device, behavioral program, surgery, or other intervention) is tested for a measurable outcome. If a project meets that definition, the applicant is directed to use a different funding mechanism specifically intended for clinical trials. The announcement also points applicants to the program's general application instructions (including guidance on human subjects, human subjects data, and human anatomical substances) to ensure compliance with the required protections and documentation.

A key requirement is that applicants must include preliminary data relevant to the proposed research. Importantly, the preliminary data do not have to come from prior ASD-specific research; unpublished results from the PI's lab, the research team, or named collaborators can be used even if they originate outside the autism field, as long as they credibly support the proposed direction. Beyond preliminary data, proposals are expected to rest on a strong scientific rationale built through careful reasoning and a critical review of the existing literature, showing reviewers that the idea is both bold and scientifically grounded.

The FY10 version of the award also emphasizes collaboration through a Multiple PI option. Up to three investigators can apply together on one unified project, with each investigator recognized as a PI and receiving a separate award. One person serves as the Initiating PI and handles most administrative responsibilities, while the others serve as Partnering PIs. The team must submit one integrated proposal focused on a shared central ASD research question, and the application should make it clear that intellectual contribution and effort are meaningfully shared across the team. Multidisciplinary and multi-organizational collaborations are permitted, but multi-organization teams are expected to include practical communication plans and to address how they will handle potential intellectual property and material property issues in a way that prevents collaboration barriers and supports smooth project execution.

Administratively, the opportunity was posted in mid-February 2010, with a closing date of July 28, 2010, and it is associated with CFDA 12.420 (Military Medical Research and Development). For applicants needing assistance, the announcement lists support contacts for accessing the full announcement and for the CDMRP electronic submission help desk. Overall, the award is best suited for teams with compelling preliminary evidence and a clearly articulated, non-incremental research concept that can shift thinking or capabilities in ASD research without crossing into clinical trial territory.

DoD Autism Idea Development Award (W81XWH-10-ARP-IDA) - FAQs

What is the DoD Autism Idea Development Award?

The Autism Idea Development Award (Funding Opportunity Number W81XWH-10-ARP-IDA) is a Department of the Army/USAMRAA funding opportunity under the Autism Research Program (ARP). Its purpose is to support innovative, high-impact research intended to deepen understanding of autism spectrum disorder (ASD) and to be positioned to ultimately improve real-world outcomes for individuals with autism.

What kind of funding mechanism is this?

This opportunity uses a grant/cooperative agreement structure and falls within the science and technology research and development category.

How much total funding is expected and how many awards will be made?

The estimated total program funding level is about $3,000,000, with an expectation of roughly 5 awards.

Is cost sharing or matching required?

No. The opportunity is described as having no cost-sharing or matching requirement.

Who is eligible to apply?

The announcement indicates the opportunity is broadly open to eligible applicants. Specific eligibility categories are not detailed in the summary provided, so applicants should rely on the full announcement and the program's general application instructions for eligibility details.

What is the central purpose of this award?

The central purpose is idea development. The award is intended to support projects that introduce genuinely original concepts, tools, or approaches rather than incremental extensions of previously published work.

What makes an application competitive?

Competitiveness depends heavily on two core review priorities: impact and innovation. Applicants are expected to clearly describe both (especially what is innovative and why it matters for ASD).

What does "impact" mean in this program?

Impact means the proposed work should make an important, original contribution to ASD understanding and have a believable path toward improving outcomes for individuals with autism.

What does "innovation" mean for this award?

Innovation means the research should bring something meaningfully new. Examples mentioned include a new paradigm, a challenge to prevailing assumptions, a fresh perspective on an existing problem, or a novel method or technology (including creative adaptations of existing methods).

Do applicants need to explicitly explain the innovation?

Yes. The program expects applicants to explicitly spell out what is innovative about the project and why that innovation matters for ASD.

Is incremental research (small extensions of existing work) appropriate?

No. The award is aimed at genuinely original concepts and approaches, not incremental extensions of previously published research.

Is human subjects research allowed?

Yes. Human subjects research is allowed under this opportunity, subject to required protections and documentation described in the program's general application instructions.

Are clinical trials allowed under this award?

No. There is a firm restriction that studies must be conducted without clinical trials.

How does the announcement define a clinical trial?

The announcement uses a standard definition: a clinical trial is a prospective human study in which an intervention is tested for a measurable outcome. Interventions can include a drug, device, behavioral program, surgery, or other intervention.

What should applicants do if their project meets the definition of a clinical trial?

If the project meets the clinical trial definition, the applicant is directed to use a different funding mechanism specifically intended for clinical trials.

Are there special instructions for human subjects, data, or human biological materials?

Yes. The opportunity points applicants to the program's general application instructions, including guidance related to human subjects, human subjects data, and human anatomical substances, to ensure compliance with protections and required documentation.

Is preliminary data required?

Yes. Applicants must include preliminary data relevant to the proposed research.

Does the preliminary data have to be ASD-specific?

No. The preliminary data do not have to come from prior ASD-specific research. Unpublished results from the PI's lab, the research team, or named collaborators may be used even if they originate outside the autism field, as long as they credibly support the proposed direction.

Beyond preliminary data, what else must support the proposal?

Proposals are expected to be grounded in a strong scientific rationale built through careful reasoning and a critical review of existing literature, showing reviewers that the idea is both bold and scientifically grounded.

Is a Multiple PI application option available?

Yes. The FY10 version emphasizes collaboration through a Multiple PI option.

How many investigators can be included as PIs under the Multiple PI option?

Up to three investigators can apply together on one unified project.

How are awards handled for Multiple PI teams?

Each investigator is recognized as a PI and receives a separate award, while the team submits one integrated proposal.

What is the difference between an Initiating PI and Partnering PIs?

One person serves as the Initiating PI and handles most administrative responsibilities. The others serve as Partnering PIs.

What does the application need to show about the Multiple PI collaboration?

The application should make clear that intellectual contribution and effort are meaningfully shared across the team, and the project should be unified around a shared central ASD research question.

Are multidisciplinary and multi-organization collaborations permitted?

Yes. Multidisciplinary and multi-organizational collaborations are permitted.

What is expected for collaborations across multiple organizations?

Multi-organization teams are expected to include practical communication plans and to address how potential intellectual property and material property issues will be handled to prevent collaboration barriers and support smooth project execution.

When was this opportunity posted and when did it close?

The opportunity was posted in mid-February 2010, with a closing date of July 28, 2010.

What CFDA number is associated with this funding opportunity?

This opportunity is associated with CFDA 12.420 (Military Medical Research and Development).

Where can applicants get help or support?

The announcement lists support contacts for accessing the full announcement and for the CDMRP electronic submission help desk.

What types of projects are best suited for this award?

This award is best suited for teams with compelling preliminary evidence and a clearly articulated, non-incremental research concept that can shift thinking or capabilities in ASD research, while staying outside clinical trial territory.

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