Opportunity Information: Apply for W81XWH 12 ARP IDA

  • The Dept. of the Army USAMRAA in the science and technology and other research and development sector is offering a public funding opportunity titled "DoD Autism Idea Development Award" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 12.420 Military Medical Research and Development.
  • This funding opportunity was created on May 2, 2012 and posted on May 2, 2012.
  • Applicants must submit their applications by Sep 20, 2012. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $3,200,000.00 to eligible and selected applicants.
  • The number of recipients for this funding is limited to 5 candidate(s).
  • Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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Opportunity Summary:

The DoD Autism Idea Development Award (Funding Opportunity Number W81XWH-12-ARP-IDA) was a discretionary research funding opportunity administered by the U.S. Department of the Army through USAMRAA under the Autism Research Program (ARP). It was designed to back early-stage but high-impact, innovative ideas that could meaningfully advance scientific understanding of autism spectrum disorder (ASD) and, over time, translate into better outcomes for individuals with autism. The mechanism supported both grants and cooperative agreements and sat within the Science and Technology / Research and Development category under CFDA 12.420 (Military Medical Research and Development). In total, the program anticipated making about five awards with an estimated combined funding level of $3.2 million, and it did not require cost sharing or matching funds.

The core purpose of the award was to push forward new concepts and approaches that could reshape or accelerate ASD research, especially work that benefits from multidisciplinary collaboration. The announcement explicitly encouraged teams that bridge fields such as special education, biomedical science, and preclinical research, reflecting an emphasis on integrating perspectives from human development and learning sciences with biological and mechanistic investigation. In practical terms, the ARP was looking for projects that did more than incrementally extend existing work; it aimed to catalyze bold, well-justified ideas that could open new lines of inquiry or validate new tools the field needs.

A major technical priority highlighted in the description was the development and validation of biologically relevant animal models of autism. Applicants were expected to justify why a proposed model was relevant, including its relationship to a particular subgroup within the autism spectrum when appropriate. This subgroup relevance emphasis suggests the program was sensitive to ASD heterogeneity and wanted models that map to meaningful biological or clinical variation rather than one-size-fits-all representations. Alongside model development, the opportunity prioritized research examining how immunological responses relate to ASD, signaling interest in the intersections between immune function, neurodevelopment, and autism-related outcomes.

Another key theme was leveraging existing resources to strengthen study power and feasibility. The ARP encouraged investigators to use already-available biological samples, established clinical populations, and existing databases to test hypotheses more efficiently and with stronger statistical power than might be possible in a small, newly assembled cohort. This focus indicates the award valued smart study design and resource utilization, especially when it could accelerate the pace of discovery or enable more definitive tests of innovative ideas.

In terms of eligibility, the opportunity was broadly open (unrestricted) to any type of applicant entity, subject to any additional clarifications that would have been provided in the full announcement. The funding notice was posted on May 2, 2012, with a closing date of September 20, 2012, and it was later archived on October 20, 2012. For administrative support, applicants were directed to the CDMRP Help Desk (help@cdmrp.org, 301-682-5507) for issues accessing the full announcement materials.

FAQs: DoD Autism Idea Development Award (W81XWH-12-ARP-IDA)

What is the DoD Autism Idea Development Award?

The DoD Autism Idea Development Award (Funding Opportunity Number W81XWH-12-ARP-IDA) was a discretionary research funding opportunity under the Department of Defense Autism Research Program (ARP). It was intended to support early-stage, high-impact, innovative ideas aimed at advancing scientific understanding of autism spectrum disorder (ASD) and, over time, improving outcomes for individuals with autism.

Which agency administered this funding opportunity?

The opportunity was administered by the U.S. Department of the Army through USAMRAA, under the DoD Autism Research Program (ARP).

What kinds of projects was the award designed to support?

The award focused on bold, well-justified concepts and approaches that could reshape or accelerate ASD research, rather than incremental extensions of existing work. It emphasized innovative ideas that could open new lines of inquiry or help validate new tools needed in the field.

Did the award emphasize multidisciplinary research?

Yes. The announcement explicitly encouraged multidisciplinary teams, including collaborations that bridge areas such as special education, biomedical science, and preclinical research. This reflected an interest in integrating perspectives from human development and learning sciences with biological and mechanistic investigation.

What were the major technical research priorities mentioned?

Key priorities included (1) development and validation of biologically relevant animal models of autism, and (2) research examining relationships between immunological responses and ASD.

What did the opportunity say about animal models of autism?

A major priority was the development and validation of biologically relevant animal models. Applicants were expected to justify why a proposed model was relevant, including its relationship to a particular subgroup within the autism spectrum when appropriate.

Why did the opportunity mention ASD subgroups in relation to animal models?

The description emphasized subgroup relevance, suggesting the program was sensitive to ASD heterogeneity and wanted models that map to meaningful biological or clinical variation rather than one-size-fits-all representations.

What did the opportunity say about immunology and autism?

It prioritized research examining how immunological responses relate to ASD, indicating interest in connections among immune function, neurodevelopment, and autism-related outcomes.

Were applicants encouraged to use existing samples, populations, or databases?

Yes. The ARP encouraged leveraging already-available biological samples, established clinical populations, and existing databases to strengthen feasibility and statistical power and to test hypotheses efficiently.

Why did the program encourage use of existing resources?

The opportunity indicated that using existing resources could improve study power and feasibility compared with small newly assembled cohorts, potentially accelerating discovery and enabling more definitive tests of innovative ideas.

What funding mechanisms were supported (grant vs. cooperative agreement)?

The mechanism supported both grants and cooperative agreements.

What category and CFDA listing was associated with this opportunity?

It was listed under the Science and Technology / Research and Development category and associated with CFDA 12.420 (Military Medical Research and Development).

How many awards were anticipated and what was the estimated total funding?

The program anticipated making about five awards, with an estimated combined funding level of $3.2 million.

Did the opportunity require cost sharing or matching funds?

No. The announcement stated that it did not require cost sharing or matching funds.

Who was eligible to apply?

Eligibility was described as broadly open (unrestricted) to any type of applicant entity, subject to any additional clarifications that would have been provided in the full announcement.

When was the funding notice posted and when did it close?

The funding notice was posted on May 2, 2012, and the closing date was September 20, 2012.

Was this opportunity later archived?

Yes. It was archived on October 20, 2012.

What should an applicant do if they had trouble accessing the full announcement materials?

For administrative support and issues accessing the full announcement materials, applicants were directed to the CDMRP Help Desk at help@cdmrp.org or 301-682-5507.

What was the overall goal of the award in terms of long-term impact?

The award sought to advance scientific understanding of ASD in ways that could translate over time into better outcomes for individuals with autism, by catalyzing innovative, high-impact early-stage research.

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