Opportunity Information: Apply for W81XWH 09 ARP IDEA

  • The Dept. of the Army USAMRAA in the science and technology and other research and development sector is offering a public funding opportunity titled "DoD Autism Research Program Idea Award" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 12.420 Military Medical Research and Development.
  • This funding opportunity was created on Feb 1, 2009 and posted on Feb 1, 2009.
  • Applicants must submit their applications by Jul 22, 2009. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $3,900,000.00 to eligible and selected applicants.
  • The number of recipients for this funding is limited to 7 candidate(s).
  • Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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Opportunity Summary:

The Department of Defense Autism Research Program (ARP) Idea Award (Funding Opportunity Number W81XWH-09-ARP-IDEA) is a competitive federal funding opportunity administered through the U.S. Army Medical Research Acquisition Activity (USAMRAA). It is intended to support high-impact, innovative research that improves scientific understanding of autism spectrum disorder (ASD) and ultimately contributes to a better quality of life for individuals with ASD. A key feature of this mechanism is its emphasis on fresh, unconventional, or early-stage concepts; proposals are not required to include preliminary data, which lowers the barrier for investigators who want to test a new hypothesis, explore a novel approach, or open up an emerging research direction that could meaningfully shift the field.

The scope is broad and welcomes applications across the full range of ASD research, including basic science, translational studies, clinical research, behavioral research, and epidemiology. Even with this wide scope, the FY09 version of the program highlights specific community-driven needs and explicitly encourages projects in two priority areas. The first priority is co-morbidity, meaning research that addresses conditions and functional challenges that commonly occur alongside ASD and can significantly affect daily functioning and health outcomes. Examples listed in the announcement include gastrointestinal disorders, sleep problems, behavioral challenges, speech and language issues, psychiatric conditions, seizures, immune dysfunction, motor and sensory deficits, metabolic dysfunction, and the ways ASD can affect intellectual ability. Research in this area might focus on understanding mechanisms, improving detection, clarifying clinical subtypes, or developing strategies to reduce the burden of these co-occurring issues.

The second priority area is predictors for treatment outcome, with an emphasis on identifying markers that can help forecast how well a given intervention will work for an individual or subgroup. The announcement specifically calls out biomarkers, clinical characteristics, and other phenotypic markers that could predict response to treatments, including both traditional approaches and complementary and alternative interventions. In practical terms, this area supports work aimed at moving the field toward more personalized or stratified care, where clinicians and families can make better-informed decisions about which therapies are more likely to help, which might be ineffective, and which populations may need different approaches.

In terms of award structure and logistics, this opportunity was offered as either a grant or a cooperative agreement under the Science and Technology/Research and Development category, and it did not require cost sharing or matching funds. The total estimated funding associated with the opportunity was about $3.9 million, with an expected seven awards. Eligibility was described as unrestricted, meaning applications were open to a wide range of applicant types, subject to any additional eligibility clarifications included in the full announcement.

The opportunity was originally posted on February 1, 2009, with a closing date of July 22, 2009, and it was archived on August 21, 2009. It is associated with CFDA number 12.420 (Military Medical Research and Development). For applicant support, the announcement provided points of contact for assistance accessing the full announcement and for submission support through the CDMRP eReceipt system, including phone numbers and email addresses for the program and help desk.

FAQs: DoD Autism Research Program (ARP) Idea Award (W81XWH-09-ARP-IDEA)

What is the ARP Idea Award (W81XWH-09-ARP-IDEA)?

The Autism Research Program (ARP) Idea Award is a competitive federal funding opportunity from the U.S. Department of Defense (DoD). It supports high-impact, innovative research intended to improve scientific understanding of autism spectrum disorder (ASD) and ultimately contribute to better quality of life for individuals with ASD.

Who administers this funding opportunity?

The opportunity is administered through the U.S. Army Medical Research Acquisition Activity (USAMRAA).

What is the main goal of this award mechanism?

The central goal is to fund fresh, unconventional, or early-stage ASD research ideas that could open new directions, test new hypotheses, or meaningfully shift the field.

Is preliminary data required to apply?

No. A key feature of this mechanism is that proposals are not required to include preliminary data, which is intended to lower the barrier for investigators pursuing new or early-stage concepts.

What types of autism research are within scope?

The scope is broad and welcomes applications across the full range of ASD research, including basic science, translational studies, clinical research, behavioral research, and epidemiology.

Does the FY09 ARP Idea Award emphasize any particular research priorities?

Yes. While the overall scope is broad, the FY09 version explicitly encourages projects in two priority areas: (1) co-morbidity and (2) predictors for treatment outcome.

What does the program mean by "co-morbidity" as a priority area?

Co-morbidity refers to conditions and functional challenges that commonly occur alongside ASD and can significantly affect daily functioning and health outcomes. The program encourages research addressing these co-occurring issues.

What are examples of co-morbidities or related challenges mentioned in the announcement?

Examples listed include gastrointestinal disorders, sleep problems, behavioral challenges, speech and language issues, psychiatric conditions, seizures, immune dysfunction, motor and sensory deficits, metabolic dysfunction, and ways ASD can affect intellectual ability.

What kinds of research approaches could fit under the co-morbidity priority?

Projects could focus on understanding mechanisms, improving detection, clarifying clinical subtypes, or developing strategies to reduce the burden of co-occurring conditions and functional challenges.

What is the second priority area, "predictors for treatment outcome"?

This priority focuses on identifying markers that can help forecast how well an intervention will work for an individual or subgroup, supporting progress toward more personalized or stratified care in ASD.

What types of predictors does the announcement specifically call out?

The announcement specifically references biomarkers, clinical characteristics, and other phenotypic markers that could predict response to treatments.

Does the predictors priority include complementary and alternative interventions?

Yes. The announcement notes predictors for treatment outcome in relation to traditional approaches as well as complementary and alternative interventions.

What award instruments were available under this opportunity?

This opportunity was offered as either a grant or a cooperative agreement.

What category is this opportunity associated with?

It falls under the Science and Technology/Research and Development category.

Was cost sharing or matching required?

No. The opportunity did not require cost sharing or matching funds.

How much total funding was estimated for this opportunity?

The total estimated funding associated with the opportunity was about $3.9 million.

How many awards were expected?

The announcement anticipated approximately seven awards.

Who was eligible to apply?

Eligibility was described as unrestricted, meaning applications were open to a wide range of applicant types, subject to any additional eligibility clarifications included in the full announcement.

When was the opportunity posted and when did it close?

It was originally posted on February 1, 2009, and the closing date was July 22, 2009.

What does it mean that the opportunity was archived?

The listing was archived on August 21, 2009, indicating the specific FY09 posting is no longer active for new submissions.

What CFDA number is associated with this funding opportunity?

The opportunity is associated with CFDA number 12.420, Military Medical Research and Development.

Where were applicants directed for submission support?

The announcement provided support resources for submission through the CDMRP eReceipt system, including help desk contact information (phone numbers and email addresses).

Were there contacts for help accessing the full announcement?

Yes. The announcement listed points of contact for assistance accessing the full announcement, along with phone numbers and email addresses for program support.

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