Opportunity Information: Apply for W81XWH 15 BCRP DIA

  • The Dept. of the Army USAMRAA in the science and technology and other research and development sector is offering a public funding opportunity titled "DoD Breast Cancer Distinguished Investigator Award" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 12.420 Military Medical Research and Development.
  • This funding opportunity was created on Mar 3, 2015 and posted on Mar 3, 2015.
  • Applicants must submit their applications by Jul 28, 2015. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $14,400,000.00 to eligible and selected applicants.
  • The number of recipients for this funding is limited to 3 candidate(s).
  • Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
Apply for W81XWH 15 BCRP DIA

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Opportunity Summary:

The DoD Breast Cancer Research Program (BCRP) Distinguished Investigator Award is designed to back well established, highly respected scientific leaders who want to take a bold swing at breast cancer using ideas that are genuinely new for them. The program is looking for principal investigators with a strong, widely recognized track record of groundbreaking work, clear evidence of leadership in their field, and a history of building productive collaborations. The overall purpose is to accelerate progress toward ending breast cancer by empowering top tier investigators to bring exceptional creativity and vision to breast cancer questions, including investigators coming from outside traditional breast cancer research.

A defining requirement of this award is that the proposed project must represent a fundamental shift from the PI's existing body of published work rather than an extension of what they already do. In other words, the application should not look like an incremental next step from the PI's prior research program. Instead, the PI must propose a fresh direction that addresses one or more of the BCRP overarching challenges, aiming for ideas that could change the trajectory of the field. High risk, high reward concepts are explicitly welcomed, and extensive preliminary data are not mandatory, but the proposal still needs to be scientifically rigorous: every application must include a well formulated, testable hypothesis supported by a strong scientific rationale.

The opportunity is open to investigators from any discipline, and prior experience in breast cancer research is not required as long as the work is clearly focused on breast cancer. This is meant to encourage cross disciplinary innovation, where researchers from other areas can bring novel tools, models, or conceptual frameworks into breast cancer research. At the same time, the program expects applicants to build the right team to execute the work. If the PI does not already have breast cancer expertise, the research team must include at least one collaborator who does have breast cancer experience to ensure the project is grounded in the realities of the disease and the current state of the science.

Another central element is structured involvement of breast cancer consumer advocates. The PI's team must include two or more consumer advocates who are breast cancer survivors and active participants in a breast cancer advocacy organization. These advocates must be independent lay representatives: they cannot be employees of any organization participating in the application, and their advocate role cannot be tied to their employment. They are expected to have enough familiarity with breast cancer research and current breast cancer issues to contribute meaningfully, with responsibilities centered on providing objective input on the research direction and the potential impact for people living with breast cancer or at risk for developing it.

Administratively, this funding opportunity (W81XWH-15-BCRP-DIA) was offered by the Department of the Army, U.S. Army Medical Research Acquisition Activity (USAMRAA), under CFDA 12.420 (Military Medical Research and Development). The instrument type allowed included cooperative agreements and grants, and the opportunity did not require cost sharing or matching. The program anticipated making about three awards, with an estimated total funding level of $14.4 million. Eligibility was listed as unrestricted, meaning it was broadly open to applicant organization types, subject to any additional eligibility clarifications in the full announcement. The opportunity was originally posted March 3, 2015, with a closing date of July 28, 2015, and it was archived August 27, 2015. For access or submission issues, the announcement directed applicants to the CDMRP Help Desk (help@eBRAP.org, 301-682-5507).

FAQs: DoD Breast Cancer Research Program (BCRP) Distinguished Investigator Award

What is the BCRP Distinguished Investigator Award intended to support?

The DoD Breast Cancer Research Program (BCRP) Distinguished Investigator Award is designed to support well established, highly respected scientific leaders who want to pursue bold, high impact breast cancer research ideas that are genuinely new for them. The goal is to accelerate progress toward ending breast cancer by enabling top tier investigators to bring exceptional creativity and vision to breast cancer questions, including investigators coming from outside traditional breast cancer research.

Who is the ideal principal investigator (PI) for this opportunity?

The opportunity targets principal investigators who have a strong, widely recognized track record of groundbreaking work, clear evidence of leadership in their field, and a history of building productive collaborations.

Does the proposed project need to be different from the PI's prior work?

Yes. A defining requirement is that the project must represent a fundamental shift from the PI's existing body of published work. The application should not look like an incremental extension of the PI's prior research program. Instead, the PI must propose a fresh direction that addresses one or more BCRP overarching challenges and aims for ideas that could change the trajectory of the field.

Are high risk, high reward ideas encouraged?

Yes. High risk, high reward concepts are explicitly welcomed, as long as the proposal remains scientifically rigorous.

Is extensive preliminary data required?

No. Extensive preliminary data are not mandatory. However, the application must still be scientifically rigorous and include a well formulated, testable hypothesis supported by a strong scientific rationale.

Does the project have to be focused on breast cancer?

Yes. Prior experience in breast cancer research is not required, but the proposed work must be clearly focused on breast cancer.

Can investigators from any discipline apply?

Yes. The opportunity is open to investigators from any discipline. The program is intended to encourage cross disciplinary innovation by bringing novel tools, models, or conceptual frameworks into breast cancer research.

If the PI is new to breast cancer research, is breast cancer expertise required on the team?

Yes. If the PI does not already have breast cancer expertise, the research team must include at least one collaborator with breast cancer experience to ensure the project is grounded in the realities of the disease and the current state of the science.

Are breast cancer consumer advocates required to be part of the research team?

Yes. The PI's team must include two or more breast cancer consumer advocates.

Who qualifies as a consumer advocate for this award?

Consumer advocates must be breast cancer survivors and active participants in a breast cancer advocacy organization. They are expected to be independent lay representatives who can provide objective input.

Are there independence requirements for the consumer advocates?

Yes. The advocates cannot be employees of any organization participating in the application, and their advocate role cannot be tied to their employment.

What are consumer advocates expected to do on the project?

Their responsibilities are centered on providing objective input on the research direction and the potential impact for people living with breast cancer or at risk for developing it. They are expected to have enough familiarity with breast cancer research and current breast cancer issues to contribute meaningfully.

Which agency offered this funding opportunity?

The opportunity (W81XWH-15-BCRP-DIA) was offered by the Department of the Army, U.S. Army Medical Research Acquisition Activity (USAMRAA), under CFDA 12.420 (Military Medical Research and Development).

What funding instrument types were allowed?

The instrument type allowed included cooperative agreements and grants.

Was cost sharing or matching required?

No. The opportunity did not require cost sharing or matching.

How many awards were anticipated, and what was the total estimated funding?

The program anticipated making about three awards, with an estimated total funding level of $14.4 million.

Who was eligible to apply?

Eligibility was listed as unrestricted, meaning it was broadly open to applicant organization types, subject to any additional eligibility clarifications in the full announcement.

When was the opportunity posted, and when did it close?

It was originally posted March 3, 2015, with a closing date of July 28, 2015.

Is this opportunity still active?

No. The opportunity was archived August 27, 2015.

Where should applicants go for access or submission issues?

For access or submission issues, applicants were directed to the CDMRP Help Desk at help@eBRAP.org or 301-682-5507.

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