Opportunity Information: Apply for W81XWH 09 BCRP IDEA
Apply for W81XWH 09 BCRP IDEA
- The Dept. of the Army USAMRAA in the science and technology and other research and development sector is offering a public funding opportunity titled "DoD Breast Cancer Idea Award" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 12.420 Military Medical Research and Development.
- This funding opportunity was created on Feb 2, 2009 and posted on Feb 2, 2009.
- Applicants must submit their applications by Apr 8, 2009. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $47,300,000.00 to eligible and selected applicants.
- The number of recipients for this funding is limited to 70 candidate(s).
- Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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Opportunity Summary:
The DoD Breast Cancer Research Program (BCRP) Idea Award (Funding Opportunity Number W81XWH-09-BCRP-IDEA) is a Department of the Army/USAMRAA funding opportunity intended to push truly new breast cancer research concepts that are still early in development but could open up major new directions. The award is aimed at conceptually innovative, high risk/high reward projects that could lead to critical discoveries or meaningful advances that help accelerate the eradication of breast cancer. Applicants are expected to propose a clearly defined, testable hypothesis backed by strong scientific rationale, and proposals can come from any research area relevant to breast cancer, including basic, translational, clinical, behavioral, and epidemiological research.
A key feature of this mechanism is that it is not designed for heavily pre-validated projects. Preliminary data is specifically described as not consistent with the intent of the Idea Award. While applicants are not barred from including preliminary findings, reviewers are not supposed to treat preliminary data as the foundation of the proposal. Instead, the application needs to stand on the strength of the idea itself: why it is scientifically compelling, how it can be tested, and why it could change the field if it works. In practice, this means the proposal should read as an argument for a bold, well-reasoned hypothesis and an approach that can generate impactful new data, rather than an incremental extension of prior results.
Review emphasis is placed most heavily on two criteria: Innovation and Impact. Innovation, in this context, means more than simply applying a known method to a new dataset or repeating established work in a slightly different setting. The BCRP describes innovative research as work that introduces a new paradigm, challenges current paradigms, or reframes an existing problem in an original way. To make the boundaries clear, the announcement lists examples of work that is considered not innovative and therefore not appropriate for funding under this mechanism. These include projects focused primarily on small molecule screening or genomic/proteomic screening; testing a hypothesis that has already been tested but just in a different cell line or population (including moving a hypothesis from another cancer type into breast cancer without a genuinely new conceptual leap); using a published set of in vitro assays simply to further characterize a model; adding known biomarkers into in vitro or clinical models without a novel conceptual advance; taking the next logical step in an existing research line; or proposing an incremental advance over published data. The overall message is that the program is not looking to pay for routine, confirmatory, or straightforward follow-on work, even if it is competently designed.
Impact is defined in terms of the project’s potential to significantly accelerate progress toward ending breast cancer. The burden is placed on the Principal Investigator to spell out, directly and convincingly, what makes the concept transformative and how success would meaningfully shift understanding, prevention, detection, or treatment. Applicants are expected to articulate not only what they will do, but why it matters in a big-picture way for breast cancer outcomes and future research directions.
A notable feature added for FY09 is a Collaborative Option that supports a two-investigator model with two PIs: an Initiating PI and a Partnering PI. This option is meant to encourage meaningful collaborations where each investigator contributes different strengths, whether from similar or very different scientific disciplines, and where the partnership is essential to the research question. While new collaborations are encouraged, they are not required; however, the collaboration must be centered on a completely new research idea. Simply continuing or extending an existing collaboration is explicitly described as not meeting the intent of the mechanism. The two PIs submit a single, jointly prepared application, but the announcement notes that each PI has different submission requirements. Importantly, the application must explain why the collaboration is necessary, how the combined expertise improves the approach, and why the work should be done together rather than as separate projects.
Administratively, this was a discretionary funding opportunity using grant and cooperative agreement instruments, categorized under science and technology and other research and development. The program anticipated about 70 awards, with an estimated total funding level of $47.3 million. The CFDA number listed is 12.420 (Military Medical Research and Development). Eligibility is described as unrestricted (open to any type of entity), subject to any additional eligibility clarifications in the full text of the announcement. There is no cost-sharing or matching requirement. The opportunity was posted February 2, 2009, with an application closing date of April 8, 2009, and an archive date of May 8, 2009. For support, the announcement provides contact points for assistance accessing the announcement and for technical submission help through the CDMRP help resources.
FAQs: DoD Breast Cancer Research Program (BCRP) Idea Award (W81XWH-09-BCRP-IDEA)
What is the BCRP Idea Award?
The BCRP Idea Award (Funding Opportunity Number W81XWH-09-BCRP-IDEA) is a Department of the Army/USAMRAA funding opportunity designed to push truly new breast cancer research concepts that are still early in development but could open up major new directions for the field.
What is the main goal of this award mechanism?
The mechanism is aimed at conceptually innovative, high risk/high reward projects that could lead to critical discoveries or meaningful advances that help accelerate the eradication of breast cancer.
What types of breast cancer research areas are allowed?
Applications may come from any research area relevant to breast cancer, including basic, translational, clinical, behavioral, and epidemiological research.
What must applicants propose in their applications?
Applicants are expected to propose a clearly defined, testable hypothesis that is supported by strong scientific rationale. The proposal should make a compelling case for why the idea is scientifically important, how it can be tested, and why it could change the field if successful.
Is preliminary data required for the Idea Award?
No. Preliminary data is described as not consistent with the intent of the Idea Award. While preliminary findings are not prohibited, reviewers are not supposed to treat preliminary data as the foundation of the proposal.
If preliminary data is included, how should it be used?
If included, preliminary data should not serve as the primary justification for the project. The application is expected to stand primarily on the strength of the concept, the scientific rationale, and the proposed approach for testing the hypothesis.
What is the application supposed to emphasize instead of extensive pre-validation?
The proposal should read as a strong argument for a bold, well-reasoned hypothesis and an approach capable of generating impactful new data, rather than an incremental extension of prior results.
What are the most heavily weighted review criteria?
Review emphasis is placed most heavily on Innovation and Impact.
How does the BCRP define Innovation for this award?
Innovation is defined as more than applying a known method to a new dataset or repeating established work in a slightly different setting. Innovative research is described as work that introduces a new paradigm, challenges current paradigms, or reframes an existing problem in an original way.
What kinds of projects are described as not innovative and not appropriate for this mechanism?
The announcement lists examples of work considered not innovative and therefore not appropriate, including:
- Projects focused primarily on small molecule screening or genomic/proteomic screening
- Testing a hypothesis that has already been tested, but only in a different cell line or population
- Moving a hypothesis from another cancer type into breast cancer without a genuinely new conceptual leap
- Using a published set of in vitro assays simply to further characterize a model
- Adding known biomarkers into in vitro or clinical models without a novel conceptual advance
- Taking the next logical step in an existing research line
- Proposing an incremental advance over published data
Does the program fund routine or confirmatory follow-on studies?
No. The overall message is that the program is not looking to fund routine, confirmatory, or straightforward follow-on work, even if it is competently designed.
How is Impact defined for this award?
Impact is defined in terms of the project’s potential to significantly accelerate progress toward ending breast cancer. Applicants are expected to explain convincingly what makes the concept transformative and how success would meaningfully shift understanding, prevention, detection, or treatment.
What does the program expect applicants to say about why the project matters?
Applicants are expected to articulate not only what they will do, but why it matters in a big-picture way for breast cancer outcomes and for shaping future research directions.
What is the FY09 Collaborative Option?
For FY09, the opportunity includes a Collaborative Option that supports a two-investigator model with two PIs: an Initiating PI and a Partnering PI.
What is the purpose of the Collaborative Option?
The Collaborative Option is meant to encourage meaningful collaborations where each investigator contributes different strengths (from similar or very different disciplines) and where the partnership is essential to the research question.
Are new collaborations required to apply under the Collaborative Option?
No. New collaborations are encouraged but not required. However, the collaboration must be centered on a completely new research idea.
Can an existing collaboration be continued or extended under the Collaborative Option?
No. Simply continuing or extending an existing collaboration is explicitly described as not meeting the intent of the mechanism.
How is the application submitted under the Collaborative Option?
The two PIs submit a single, jointly prepared application. The announcement also notes that each PI has different submission requirements.
What must the application explain about the collaboration?
The application must explain why the collaboration is necessary, how the combined expertise improves the approach, and why the work should be done together rather than as separate projects.
What federal assistance instruments are associated with this opportunity?
This was a discretionary funding opportunity using grant and cooperative agreement instruments.
What is the CFDA number for this program?
The CFDA number listed is 12.420 (Military Medical Research and Development).
What funding category does this opportunity fall under?
It is categorized under science and technology and other research and development.
How many awards were anticipated and what was the estimated total funding?
The program anticipated about 70 awards, with an estimated total funding level of $47.3 million.
Who is eligible to apply?
Eligibility is described as unrestricted (open to any type of entity), subject to any additional eligibility clarifications in the full text of the announcement.
Is cost-sharing or matching required?
No. There is no cost-sharing or matching requirement.
When was the opportunity posted and what were the key dates?
The opportunity was posted February 2, 2009. The application closing date was April 8, 2009, and the archive date was May 8, 2009.
Where can applicants get help or support for submission issues?
The announcement provides contact points for assistance accessing the announcement and for technical submission help through the CDMRP help resources.
What is the administering organization for this funding opportunity?
The opportunity is identified as a Department of the Army/USAMRAA funding opportunity under the DoD Breast Cancer Research Program (BCRP).
What is the central theme reviewers are looking for in an Idea Award application?
The central theme is a bold, scientifically compelling idea that is testable and potentially transformative for breast cancer, with the application standing on the strength of the concept rather than on extensive prior validation.
Browse more opportunities from the same category: Science and Technology and other Research and Development
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Previous opportunity: Cognition and Neuroergonomics (CAN) Collaborative Technology Alliance (CTA)
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| DoD Breast Cancer Era of Scholar Award Apply for W81XWH 09 BCRP EOHS Funding Number: W81XWH 09 BCRP EOHS Agency: Dept. of the Army USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| DOD Neurofibromatosis Postdoctoral Traineeship Award Apply for W81XWH 09 NFRP POSTDOC Funding Number: W81XWH 09 NFRP POSTDOC Agency: Dept. of the Army USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| DoD Breast Cancer HBCU/MI Partnership Training Award Apply for W81XWH 09 BCRP HPT Funding Number: W81XWH 09 BCRP HPT Agency: Dept. of the Army USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| DoD Breast Cancer Innovator Award Apply for W81XWH 09 BCRP INNOV Funding Number: W81XWH 09 BCRP INNOV Agency: Dept. of the Army USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| DOD Neurofibromatosis Exploration Hypothesis Development Award Apply for W81XWH 09 NFRP EHDA Funding Number: W81XWH 09 NFRP EHDA Agency: Dept. of the Army USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| DOD Neurofibromatosis New Investigator Award Apply for W81XWH 09 NFRP NIA Funding Number: W81XWH 09 NFRP NIA Agency: Dept. of the Army USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
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