Opportunity Information: Apply for W81XWH 14 DMDRP IIRA
Apply for W81XWH 14 DMDRP IIRA
- The Dept. of the Army USAMRAA in the science and technology and other research and development sector is offering a public funding opportunity titled "DoD Duchenne Muscular Dystrophy Investigator Initiated Research Award" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 12.420 Military Medical Research and Development.
- This funding opportunity was created on May 27, 2014 and posted on May 27, 2014.
- Applicants must submit their applications by Oct 22, 2014. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $2,016,000.00 to eligible and selected applicants.
- The number of recipients for this funding is limited to 2 candidate(s).
- Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
[Watch] Creating a grant proposal using the step-by-step wizard inside the applicant portal:
Opportunity Summary:
The DoD Duchenne Muscular Dystrophy Investigator Initiated Research Award (IIRA) is a funding opportunity under the Department of Defense Duchenne Muscular Dystrophy Research Program (DMDRP) designed to push promising Duchenne muscular dystrophy (DMD) ideas closer to real-world clinical use. The program emphasizes translational research, meaning work that deliberately connects basic laboratory science with clinical observations so that new therapies, devices, or other interventions can be developed and advanced toward patient care. A core idea behind this award is that translation is not a one-way pipeline; it is meant to be a back-and-forth process where clinical insights shape lab work and lab findings feed directly into clinical decision-making and trial design.
This particular award mechanism supports mid-stage to later-stage translational projects rather than early exploratory research. The intent is to fund studies that are mature enough to plausibly accelerate movement into clinical application. Examples of the kinds of activities the IIRA aims to support include early-phase, proof-of-principle clinical trials and correlative studies that help clarify how an intervention performs in people and how development decisions should be made going forward (for instance, linking clinical outcomes to biomarkers or other measures that inform dosing, patient selection, or monitoring). The scope also allows for certain preclinical studies, including work in animal models as well as studies involving human subjects or human anatomical substances, as long as the overall trajectory is clearly oriented toward clinical translation rather than basic discovery.
At the same time, the announcement makes clear what the award is not meant to fund. Projects centered on target discovery, broad drug screening efforts, mechanism-of-action studies, or hypothesis-driven pathophysiology research are explicitly discouraged under this mechanism. In practice, that means proposals should not be built around finding new molecular targets, running large-scale screens to identify candidate compounds, or primarily explaining disease biology for its own sake. Instead, the work should already be positioned at a stage where a therapeutic concept or intervention approach is sufficiently defined to justify translational testing, refinement, and early clinical evaluation.
From an administrative standpoint, this opportunity was posted May 27, 2014, with an original and current closing date of October 22, 2014, and an archive date of November 21, 2014. The Funding Opportunity Number is W81XWH-14-DMDRP-IIRA, and it is offered by the U.S. Army Medical Research Acquisition Activity (USAMRAA) under the Department of the Army. The instrument type is listed as a cooperative agreement or grant, and the activity category is science and technology and other research and development. The total estimated funding is $2,016,000, with an expectation of making 2 awards, and there is no cost-sharing or matching requirement. Eligibility is described as unrestricted, meaning it is broadly open to applicant entity types, subject to any additional eligibility clarifications in the full text of the announcement. The CFDA number associated with the program is 12.420 (Military Medical Research and Development).
The announcement also provides brief historical context to show selectivity and scale: since the mechanism was first offered in FY11, 51 applications had been received and 10 recommended for funding at the time of this posting. For practical assistance, applicants having trouble accessing the full announcement are directed to the CDMRP Help Desk at (301) 682-5507 or help@eBRAP.org.
FAQs: DoD Duchenne Muscular Dystrophy Investigator Initiated Research Award (IIRA)
What is the DoD Duchenne Muscular Dystrophy Investigator Initiated Research Award (IIRA)?
The Investigator Initiated Research Award (IIRA) is a funding opportunity under the Department of Defense Duchenne Muscular Dystrophy Research Program (DMDRP). It is intended to move promising Duchenne muscular dystrophy (DMD) ideas closer to real-world clinical use by supporting translational research.
What does the program mean by "translational research"?
In this opportunity, translational research is described as work that deliberately connects basic laboratory science with clinical observations so that therapies, devices, or other interventions can be developed and advanced toward patient care. The announcement emphasizes that translation is not a one-way pipeline; it is meant to be bidirectional, where clinical insights shape lab work and lab findings feed directly into clinical decision-making and trial design.
What stage of research is this award meant to support?
This mechanism supports mid-stage to later-stage translational projects rather than early exploratory research. The intent is to fund studies mature enough to plausibly accelerate movement into clinical application.
What types of studies or activities does the IIRA aim to support?
Examples listed in the announcement include early-phase, proof-of-principle clinical trials and correlative studies designed to clarify how an intervention performs in people and how development decisions should be made going forward. The announcement specifically notes work that links clinical outcomes to biomarkers or other measures that can inform dosing, patient selection, or monitoring.
Are preclinical studies allowed under this mechanism?
Yes. The scope allows certain preclinical studies, including work in animal models, as well as studies involving human subjects or human anatomical substances, as long as the overall project trajectory is clearly oriented toward clinical translation rather than basic discovery.
What kinds of projects are discouraged or not intended to be funded?
The announcement explicitly discourages projects centered on target discovery, broad drug screening efforts, mechanism-of-action studies, or hypothesis-driven pathophysiology research. In other words, proposals should not be primarily about finding new molecular targets, running large-scale screens to identify candidate compounds, or explaining disease biology for its own sake.
If my project focuses mainly on disease mechanisms or pathophysiology, is this award a good fit?
Based on the announcement language, projects primarily focused on mechanism-of-action or hypothesis-driven pathophysiology research are explicitly discouraged under this mechanism. The IIRA is positioned for work that is already oriented toward translational testing, refinement, and early clinical evaluation of a sufficiently defined therapeutic concept or intervention approach.
Do proposals need to already have a defined therapeutic concept or intervention approach?
Yes, that is the intent described. The IIRA is aimed at projects where a therapeutic concept or intervention approach is sufficiently defined to justify translational testing, refinement, and early clinical evaluation, rather than early discovery-stage work.
What is the Funding Opportunity Number for this award?
The Funding Opportunity Number is W81XWH-14-DMDRP-IIRA.
Which agency is offering this opportunity?
The opportunity is offered by the U.S. Army Medical Research Acquisition Activity (USAMRAA) under the Department of the Army, within the Department of Defense program structure described as the Duchenne Muscular Dystrophy Research Program (DMDRP).
What is the instrument type for this funding opportunity?
The instrument type is listed as a cooperative agreement or grant.
What is the activity category listed for this opportunity?
The activity category is listed as science and technology and other research and development.
How much total funding is estimated for this opportunity?
The total estimated funding is $2,016,000.
How many awards are expected to be made?
The opportunity indicates an expectation of making 2 awards.
Is cost sharing or matching required?
No. The announcement states there is no cost-sharing or matching requirement.
Who is eligible to apply?
Eligibility is described as unrestricted, meaning it is broadly open to applicant entity types, subject to any additional eligibility clarifications in the full text of the announcement.
What is the CFDA number associated with this program?
The CFDA number listed is 12.420 (Military Medical Research and Development).
When was this opportunity posted, and what were the closing dates?
The opportunity was posted on May 27, 2014. The original closing date and the current closing date are both listed as October 22, 2014. The archive date is November 21, 2014.
Does the announcement provide any context about competitiveness or prior cycles?
Yes. The announcement notes that since the mechanism was first offered in FY11, 51 applications had been received and 10 recommended for funding at the time of this posting, which is provided as historical context on selectivity and scale.
Where can applicants get help if they cannot access the full announcement?
Applicants having trouble accessing the full announcement are directed to the CDMRP Help Desk at (301) 682-5507 or help@eBRAP.org.
Browse more opportunities from the same category: Science and Technology and other Research and Development
Next opportunity: Professor, Animal Range Science, Montana State University
Previous opportunity: BLM Wilderness Program and WILD Foundation
USGrants.org Applicant Portal:
Are you interested in learning about about how to apply for this government funding opportunity? You can create a free applicant account and receive instant access to our applicant portal that many business owners like you have benefited from.
Apply for W81XWH 14 DMDRP IIRA
[Watch] how do funding administrators access proposals?
Applicants also applied for:
Applicants who have applied for this opportunity (W81XWH 14 DMDRP IIRA) also looked into and applied for these:
| Funding Opportunity |
|---|
| DoD Duchenne Muscular Dystrophy Therapeutic Idea Award Apply for W81XWH 14 DMDRP TIA Funding Number: W81XWH 14 DMDRP TIA Agency: Dept. of the Army USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| ROSES 2014 Planetary Data Archiving, Restoration, and Tools Apply for NNH14ZDA001N PDART Funding Number: NNH14ZDA001N PDART Agency: NASA Headquarters Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| Research on Golden Eagle Ecology in the U.S. Deserts (Mojave, Great Basin, Sonoran) Apply for F14AS00202 Funding Number: F14AS00202 Agency: Fish and Wildlife Service Category: Science and Technology and other Research and Development Funding Amount: $79,000 |
| DoD Tuberous Sclerosis Complex Exploration Hypothesis Development Award Apply for W81XWH 14 TSCRP EHDA Funding Number: W81XWH 14 TSCRP EHDA Agency: Dept. of the Army USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| DoD Tuberous Sclerosis Complex Idea Development Award Apply for W81XWH 14 TSCRP IDA Funding Number: W81XWH 14 TSCRP IDA Agency: Dept. of the Army USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| DoD Tuberous Sclerosis Complex Pilot Clinical Trial Award Apply for W81XWH 14 TSCRP PCTA Funding Number: W81XWH 14 TSCRP PCTA Agency: Dept. of the Army USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| DoD Neurofibromatosis Investigator Initiated Research Award Apply for W81XWH 14 NFRP IIRA Funding Number: W81XWH 14 NFRP IIRA Agency: Dept. of the Army USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| DoD Neurofibromatosis New Investigator Award Apply for W81XWH 14 NFRP NIA Funding Number: W81XWH 14 NFRP NIA Agency: Dept. of the Army USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| DoD Neurofibromatosis Clinial Trial Award Apply for W81XWH 14 NFRP CTA Funding Number: W81XWH 14 NFRP CTA Agency: Dept. of the Army USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| DoD Neurofibromatosis Exploration Hypothesis Development Award Apply for W81XWH 14 NFRP EHDA Funding Number: W81XWH 14 NFRP EHDA Agency: Dept. of the Army USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| Central Valley Project Conservation Program and Central Valley Project Improvement Act Habitat Restoration Program Apply for R14AS00050 Funding Number: R14AS00050 Agency: Bureau of Reclamation Category: Science and Technology and other Research and Development Funding Amount: $1,000,000 |
| CENTER OF EXCELLENCE Electromagnetic Interference for Extreme Electromagnetic Environments Apply for BAA AFOSR 2014 0002 Funding Number: BAA AFOSR 2014 0002 Agency: Air Force Office of Scientific Research Category: Science and Technology and other Research and Development Funding Amount: $6,000,000 |
| DoD Prostate Cancer Exploration Hypothesis Development Award Apply for W81XWH 14 PCRP EHDA Funding Number: W81XWH 14 PCRP EHDA Agency: Dept. of the Army USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| DoD Prostate Cancer Laboratory Clinical Transition Award Apply for W81XWH 14 PCRP LCTA Funding Number: W81XWH 14 PCRP LCTA Agency: Dept. of the Army USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| DoD Prostate Cancer Postdoctoral Training Award Apply for W81XWH 14 PCRP PTA Funding Number: W81XWH 14 PCRP PTA Agency: Dept. of the Army USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| DoD Prostate Cancer Physician Research Training Award Apply for W81XWH 14 PCRP PRTA Funding Number: W81XWH 14 PCRP PRTA Agency: Dept. of the Army USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| DoD Prostate Cancer Dr. Barbara Terry Koroma Health Disparity Research Award Apply for W81XWH 14 PCRP HDRA Funding Number: W81XWH 14 PCRP HDRA Agency: Dept. of the Army USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| DoD Prostate Cancer Collaborative Undergraduate Historically Black Colleges and Universities Student Summer Training Program Award Apply for W81XWH 14 PCRP STPA Funding Number: W81XWH 14 PCRP STPA Agency: Dept. of the Army USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| DoD Prostate Cancer Population Science Impact Award Apply for W81XWH 14 PCRP PSIA Funding Number: W81XWH 14 PCRP PSIA Agency: Dept. of the Army USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| Early Stage Innovations (ESI) Apply for NNH14ZOA001N 14ESI B2 Funding Number: NNH14ZOA001N 14ESI B2 Agency: NASA Headquarters Category: Science and Technology and other Research and Development Funding Amount: $500,000 |
Grant application guides and resources
It is always free to apply for government grants. However the process may be very complex depending on the funding opportunity you are applying for. Let us help you!
Apply for Grants
Premium leads for funding administrators, grant writers, and loan issuers
Thousands of people visit our website for their funding needs every day. When a user creates a grant proposal and files for submission, we pass the information on to funding administrators, grant writers, and government loan issuers.
If you manage government grant programs, provide grant writing services, or issue personal or government loans, we can help you reach your audience.
Subscribe to Leads
Request more information:
Would you like to learn more about this funding opportunity, similar opportunities to "W81XWH 14 DMDRP IIRA", eligibility, application service, and/or application tips? Submit an inquiry below:
Don't forget to subscribe to our grant alerts mailing list to receive weekly alerts on new and updated grant funding opportunities like this one in your email.