DoD Duchenne Muscular Dystrophy Therapeutic Idea Award | Apply Online

Opportunity Summary:

The DoD Duchenne Muscular Dystrophy Research Program (DMDRP) Therapeutic Idea Award (TIA) is a U.S. Army (USAMRAA) funding opportunity created to spark genuinely new and early stage therapeutic concepts for Duchenne muscular dystrophy (DMD). It is specifically meant for projects that are not yet mature, but that could quickly generate high impact results and open up new directions toward treatments. The program is framed around high risk, high reward science, with the expectation that funded work could lead to major breakthroughs or meaningful leaps forward in DMD therapeutics rather than incremental progress.

A central expectation is that proposals are driven by a clear, well-formulated, testable hypothesis supported by strong scientific reasoning. Unlike many grant mechanisms, this award is not designed to reward extensive preliminary results. Preliminary data can be included, but applicants are told not to make the application dependent on it. In practice, the reviewers are being asked to judge ideas primarily on their originality and plausibility rather than on how much supporting data the team has already generated.

The two dominant review priorities are Innovation and Impact. Innovation, in this context, means work that changes the conversation: introducing a new paradigm, challenging established assumptions, bringing forward novel therapeutic concepts or agents, or applying uniquely creative approaches that could lead to a therapy for DMD. The announcement even points to drug repurposing as one example of the kind of creative therapeutic thinking they want to encourage. At the same time, the solicitation draws a clear boundary: projects that mainly represent the next logical step based on published findings, or that are incremental extensions of existing work, are not considered innovative for this mechanism. Impact is defined as the potential for the research to meaningfully accelerate or improve therapeutic development for DMD, so the end goal is not just knowledge, but knowledge that can plausibly move toward treatment.

The FY15 version of the award also highlights biomarker discovery and qualification as a focus area, specifically pharmacodynamic, prognostic, and predictive biomarkers. The opportunity defines a biomarker as an objectively measured characteristic that indicates normal biological processes, disease processes, or biological responses to a therapeutic intervention. It further clarifies that biomarker qualification, for the purposes of this award, is an evidence-based, fit-for-purpose process that links a biomarker to an agent's effects on biological processes and clinical endpoints. The program encourages biomarkers that can be measured through minimally invasive methods, such as blood, urine, tissue sampling, or imaging. Examples mentioned include genetic or epigenetic signatures, specific genes, proteins, metabolites, and molecular, physiological, or imaging readouts, reflecting broad openness to different biomarker modalities as long as they are credible and relevant to DMD therapy development.

Administratively, this opportunity was posted June 4, 2015 under Funding Opportunity Number W81XWH-15-DMDRP-TIA and is categorized as discretionary research and development funding in the science and technology area. The funding instrument type is listed as a cooperative agreement and grant, with no cost sharing or matching requirement. The estimated total funding was $480,000 with an expectation of one award. Eligibility was listed as unrestricted, meaning it was open to essentially any type of applicant organization, subject to any additional eligibility clarifications in the full text. The application deadline for the FY15 cycle was October 21, 2015, and the opportunity was archived November 20, 2015. For access issues or help with the full announcement, the point of contact was the CDMRP Help Desk at 301-682-5507.

Browse more opportunities from the same agency: Dept. of the Army USAMRAA

Browse more opportunities from the same category: Science and Technology and other Research and Development

Next opportunity: DoD Duchenne Muscular Dystrophy Translational Leverage Award

Previous opportunity: Building Conservation Leaders for the Future Curriculum, Certificates, Internships, and Research Agenda

USGrants.org Applicant Portal:

Are you interested in learning about about how to apply for this government funding opportunity? You can create a free applicant account and receive instant access to our applicant portal that many business owners like you have benefited from.

Apply for W81XWH 15 DMDRP TIA

 

[Watch] how do funding administrators access proposals?

Applicants also applied for:

Applicants who have applied for this opportunity (W81XWH 15 DMDRP TIA) also looked into and applied for these:

 

Grant application guides and resources

It is always free to apply for government grants. However the process may be very complex depending on the funding opportunity you are applying for. Let us help you!

Apply for Grants

 

 

Premium leads for funding administrators, grant writers, and loan issuers

Thousands of people visit our website for their funding needs every day. When a user creates a grant proposal and files for submission, we pass the information on to funding administrators, grant writers, and government loan issuers.

If you manage government grant programs, provide grant writing services, or issue personal or government loans, we can help you reach your audience.

Subscribe to Leads

 

Request more information:

Would you like to learn more about this funding opportunity, similar opportunities to "W81XWH 15 DMDRP TIA", eligibility, application service, and/or application tips? Submit an inquiry below:

Don't forget to subscribe to our grant alerts mailing list to receive weekly alerts on new and updated grant funding opportunities like this one in your email.