Opportunity Information: Apply for W81XWH 15 ERP IDA
Apply for W81XWH 15 ERP IDA
- The Dept. of the Army USAMRAA in the science and technology and other research and development sector is offering a public funding opportunity titled "DoD Epilepsy Idea Development Award" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 12.420 Military Medical Research and Development.
- This funding opportunity was created on Jul 21, 2015 and posted on Jul 21, 2015.
- Applicants must submit their applications by Nov 24, 2015. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $6,800,000.00 to eligible and selected applicants.
- The number of recipients for this funding is limited to 5 candidate(s).
- Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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Opportunity Summary:
The DoD Epilepsy Idea Development Award (Funding Opportunity Number W81XWH-15-ERP-IDA) was a FY2015 research funding opportunity from the Department of the Army, administered through the U.S. Army Medical Research Acquisition Activity (USAMRAA) under the Congressionally Directed Medical Research Programs (CDMRP) Epilepsy Research Program (ERP). It supported science and technology and other research and development efforts focused on post-traumatic epilepsy (PTE), with a clear emphasis on improving understanding of both the scale of the problem and the biological or physiological mechanisms that lead to PTE. While the program is motivated by military health needs, it is explicitly framed to benefit both Service members and Veterans and, more broadly, the civilian community as well.
A defining feature of this announcement is that the Idea Development Award mechanism was being offered for the first time in FY15, signaling an intent to stimulate new lines of investigation and bring fresh approaches into the PTE space. The solicitation points applicants toward specific FY15 ERP Focus Areas (referenced in the announcement) as the organizing priorities for proposals. In practical terms, that means the program was not looking for epilepsy research in general, but rather projects that fit within the ERP-defined areas tied to traumatic brain injury (TBI) and the development of epilepsy following trauma, including work aimed at clarifying disease mechanisms and characterizing magnitude and impact.
The award was structured with two funding levels designed for different stages and scopes of research. Level I was geared toward investigator-initiated projects that may be high risk and/or high gain, which typically implies early-stage concepts, novel hypotheses, or exploratory approaches where the payoff could be significant even if the uncertainty is higher. Level II was intended for more advanced studies that could be multidisciplinary and/or involve multiple collaborators, which generally suggests a larger scope, more integration across methods or fields, and a more mature project plan. Applicants had to choose the level that best matched the proposed work, and the responsibility for selecting the appropriate level rested with the Principal Investigator.
Even though the mechanism encouraged innovative ideas, the program still expected applications at either Level I or Level II to include relevant preliminary data supporting the central research hypothesis or hypotheses. This requirement indicates that proposals needed more than a conceptual rationale; they needed some empirical foundation showing feasibility or early evidence that the idea is worth advancing. In addition, the solicitation stresses the importance of appropriate expertise on the study team: while Principal Investigators could come from any field or discipline, they needed to be at or above the Assistant Professor level (or equivalent), and the application had to demonstrate that the team had experience in both TBI and epilepsy research. This reflects the program view that credible progress on PTE depends on integrating knowledge of brain injury with epilepsy mechanisms and outcomes.
The announcement also includes a specific programmatic preference regarding clinical approaches: clinical research focusing on pharmacological interventions was not encouraged. That does not necessarily prohibit drug-related work, but it signals that the program was prioritizing other kinds of clinical research or preclinical and translational studies, particularly those aimed at understanding mechanisms, identifying pathways, improving characterization, or developing non-pharmacologic strategies aligned with the ERP focus areas.
Administratively, the opportunity was categorized as discretionary funding, with the funding instrument listed as both cooperative agreement and grant. The total estimated funding for the competition was $6.8 million, with an expectation of making about five awards. No cost sharing or matching was required, and eligibility was described as unrestricted (open to any type of entity), subject to any additional eligibility details in the full announcement. The CFDA listing associated with the opportunity was 12.420 (Military Medical Research and Development). The opportunity was posted on July 21, 2015, and the application closing date was November 24, 2015, with an archive date of December 24, 2015. For technical access issues related to the full announcement, the listed point of contact was the CDMRP Help Desk at 301-682-5507.
Frequently Asked Questions (FAQs) - DoD Epilepsy Idea Development Award (W81XWH-15-ERP-IDA, FY2015)
What is the DoD Epilepsy Idea Development Award (IDA)?
The DoD Epilepsy Idea Development Award (Funding Opportunity Number W81XWH-15-ERP-IDA) was a FY2015 research funding opportunity from the Department of the Army, administered through the U.S. Army Medical Research Acquisition Activity (USAMRAA) under the Congressionally Directed Medical Research Programs (CDMRP) Epilepsy Research Program (ERP).
Which research program is this opportunity part of?
This opportunity was part of the CDMRP Epilepsy Research Program (ERP) and was administered by USAMRAA for the Department of the Army.
What condition or topic was the award focused on?
The award focused on post-traumatic epilepsy (PTE), including research and development efforts tied to traumatic brain injury (TBI) and the development of epilepsy following trauma.
Was the program looking for epilepsy research in general?
No. The solicitation emphasized that proposals needed to fit within the FY2015 ERP Focus Areas referenced in the announcement, with priorities tied specifically to TBI-related epilepsy and PTE.
What kinds of outcomes or impacts was the program emphasizing?
The program emphasized improving understanding of both (1) the scale of the PTE problem (magnitude and impact) and (2) the biological and/or physiological mechanisms that lead to PTE.
Who was intended to benefit from the research?
While motivated by military health needs, the opportunity was explicitly framed to benefit Service members and Veterans and, more broadly, the civilian community as well.
What was distinctive about the Idea Development Award mechanism in FY2015?
The IDA mechanism was being offered for the first time in FY15, signaling an intent to stimulate new lines of investigation and encourage fresh approaches in the PTE research space.
What funding levels were available under this award?
The award was structured with two funding levels: Level I and Level II, designed for different stages and scopes of research.
What was Level I intended to support?
Level I was geared toward investigator-initiated projects that may be high risk and/or high gain, generally implying early-stage concepts, novel hypotheses, or exploratory approaches with potentially significant payoff despite higher uncertainty.
What was Level II intended to support?
Level II was intended for more advanced studies that could be multidisciplinary and/or involve multiple collaborators, typically suggesting a larger scope, more integration across methods or fields, and a more mature project plan.
Who decided whether an application should be submitted as Level I or Level II?
The responsibility for selecting the appropriate level rested with the Principal Investigator (PI), who had to choose the level that best matched the proposed work.
Did applications need preliminary data?
Yes. Even though innovative ideas were encouraged, the solicitation expected applications at either Level I or Level II to include relevant preliminary data supporting the central research hypothesis or hypotheses.
What did the preliminary data requirement imply about proposal expectations?
It indicated that proposals needed more than a conceptual rationale; they needed some empirical foundation demonstrating feasibility or early evidence that the idea was worth advancing.
What were the PI eligibility expectations regarding career level?
Principal Investigators could come from any field or discipline, but they needed to be at or above the Assistant Professor level (or equivalent).
What expertise was expected on the study team?
The application had to demonstrate that the team had experience in both traumatic brain injury (TBI) and epilepsy research, reflecting the program view that credible progress on PTE depends on integrating both areas of expertise.
Were pharmacological intervention clinical studies encouraged?
No. The announcement stated that clinical research focusing on pharmacological interventions was not encouraged, signaling a programmatic preference for other approaches aligned with the ERP focus areas.
Does "not encouraged" mean drug-related research was prohibited?
The information provided indicates it was not encouraged rather than outright prohibited, but it clearly communicated that the program was prioritizing other kinds of clinical research and/or preclinical or translational studies centered on mechanisms, pathways, characterization, magnitude, and impact.
What type of funding was this categorized as?
The opportunity was categorized as discretionary funding.
What were the listed funding instruments for this opportunity?
The funding instrument was listed as both a cooperative agreement and a grant.
How much total funding was estimated for the competition?
The total estimated funding for the competition was $6.8 million.
About how many awards were expected to be made?
The opportunity indicated an expectation of making about five awards.
Was cost sharing or matching required?
No. No cost sharing or matching was required.
Who was eligible to apply?
Eligibility was described as unrestricted (open to any type of entity), subject to any additional eligibility details in the full announcement.
What CFDA number was associated with this opportunity?
The CFDA listing associated with the opportunity was 12.420 (Military Medical Research and Development).
When was the opportunity posted?
The opportunity was posted on July 21, 2015.
What was the application closing date?
The application closing date was November 24, 2015.
When was the opportunity archived?
The archive date was December 24, 2015.
Who should applicants contact for technical access issues related to the full announcement?
For technical access issues related to the full announcement, the listed point of contact was the CDMRP Help Desk at 301-682-5507.
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