DOD FY11 Lung Cancer Investigator Initiated Translational Research Award | Apply Online

Opportunity Summary:

The DOD FY11 Lung Cancer Investigator Initiated Translational Research Award (Funding Opportunity Number W81XWH-11-LCRP-IITRA) was a U.S. Department of Defense Lung Cancer Research Program funding opportunity designed to push promising lung cancer discoveries toward real-world clinical use. The core emphasis was on translational research, meaning projects needed to deliberately connect basic science work with clinical observations in a way that accelerates movement from an initial insight to something that can be tested, applied, or otherwise used in clinical settings. The program framed translational research as more than just taking lab results and handing them off to clinicians; instead, it encouraged an iterative flow where clinical realities can shape laboratory questions and laboratory findings can loop back to improve clinical approaches.

A key feature of the opportunity was that it supported investigator-initiated ideas, so applicants were expected to propose their own concepts rather than respond to a narrow, pre-defined research topic. The announcement recognized that good translational ideas can originate from multiple starting points, including laboratory discoveries, population-based studies, and direct clinical experience. In practical terms, this meant the program was open to research directions sparked by emerging mechanistic findings, epidemiologic patterns, biomarker observations, treatment response trends, or even well-founded insights drawn from hands-on patient care and anecdotal clinical evidence, as long as the proposed work clearly aimed to bridge the gap between discovery and clinical application.

The award mechanism allowed funding as either a cooperative agreement or a grant, under the broader activity category of science and technology and other research and development. The program anticipated making about five awards, with an estimated total funding level of $4.2 million across all awards. There was no cost-sharing or matching requirement, which reduced financial barriers for applicants and made it more feasible for a wide range of organizations to compete based on scientific merit and translational potential rather than available institutional matching funds.

Eligibility was listed as unrestricted, meaning the competition was open to any type of applicant organization, subject to any additional eligibility details that may have been included in the full announcement. The sponsoring agency was the Department of the Army, administered through the U.S. Army Medical Research Acquisition Activity (USAMRAA), and the opportunity was associated with CFDA 12.420, Military Medical Research and Development. The announcement was originally posted on June 15, 2011, with an application closing date of November 9, 2011, and it was archived on December 9, 2011, indicating it was a time-limited competition for FY11 rather than an ongoing program.

Overall, the grant was structured to reward projects that could credibly demonstrate a pathway to clinical impact in lung cancer, grounded in a strong integration of laboratory and clinical reasoning. The program explicitly pushed back on the idea that translational research is a simple one-way pipeline from bench to bedside, emphasizing instead the practical reality that progress often requires feedback between clinical observation and experimental work. For applicants, that framing implied that strong proposals would not only describe a promising discovery or hypothesis but also show how clinical context informs the research plan and how the results could be positioned to move into clinical testing, validation, or implementation.

For technical access issues related to the full announcement, the listed support contact was the CDMRP Help Desk (PA HELP and eReceipt HELP) at 301-682-5507.

Browse more opportunities from the same agency: Dept. of the Army USAMRAA

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Next opportunity: DOD FY11 Lung Cancer Early Investigator Synergistic Idea Award

Previous opportunity: DOD FY11 Lung Cancer Promising Clinician Research Award

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