DOD FY11 Neurofibromatosis Clinical Trial Award | Apply Online

Opportunity Summary:

The DOD FY11 Neurofibromatosis Clinical Trial Award (Funding Opportunity Number W81XWH 11 NFRP CTA) is a U.S. Department of Defense funding opportunity managed through the Neurofibromatosis Research Program (NFRP), a program created in 1996 to improve the understanding, diagnosis, and treatment of neurofibromatosis (NF). For FY11, the program goal is framed in practical, patient-focused terms: support the strongest research efforts aimed at eliminating the real-world clinical burden of NF. Within that larger mission, this specific award mechanism is designed to push forward studies that can meaningfully change how NF or Schwannomatosis is treated or managed, with an emphasis on work that has a clear path to affecting patient care.

A central requirement of this opportunity is that the proposed project must be a clinical trial. The funding is not intended to pay for preclinical or purely laboratory-based studies, and proposals that are not actual clinical trials are outside the scope of what this mechanism will support. The announcement defines a clinical trial in a fairly standard way: it must involve prospective enrollment (accrual) of human subjects and must test an intervention in people, with measurable outcomes. The intervention can take many forms, including but not limited to a drug, biologic, medical device, surgical procedure, rehabilitation approach, behavioral intervention, or another type of structured intervention. The outcomes must be tied to something that reflects a direct effect on the human participant, such as exploratory endpoints, safety signals, effectiveness measures, and/or efficacy results. In other words, this award is aimed at studies that directly interact with patients and produce interpretable clinical data, rather than preparatory work that might someday lead to a trial.

From an administrative and funding standpoint, this is a discretionary opportunity offered by the Department of the Army through USAMRAA, under the broader category of science and technology research and development. Awards may be made as either cooperative agreements or grants, depending on the structure and level of agency involvement appropriate for the project. The total estimated funding listed for the opportunity is $2.8 million, with an expectation of making about two awards, indicating a competitive process focused on a small number of higher-impact trials rather than many smaller projects. There is no cost sharing or matching requirement specified, which generally means applicants are not required to contribute non-federal funds as a condition of receiving the award.

Eligibility is described as unrestricted, meaning it is open to any type of entity, unless additional eligibility clarifications appear in the full announcement text. Key timeline details include a posted and created date of May 3, 2011, and an application closing date of September 15, 2011 (with the archive date listed as October 15, 2011). The opportunity is associated with CFDA number 12.420, Military Medical Research and Development, which is the catalog listing used to classify federal assistance programs. For technical issues accessing the full announcement, the contact provided is the CDMRP Help Desk (PA HELP and eReceipt HELP) at 301-682-5507.

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