Opportunity Information: Apply for W81XWH 11 PCRP HDRA
Apply for W81XWH 11 PCRP HDRA
- The Dept. of the Army USAMRAA in the science and technology and other research and development sector is offering a public funding opportunity titled "DoD FY11 Prostate Cancer Health Disparity Research Award" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 12.420 Military Medical Research and Development.
- This funding opportunity was created on Apr 21, 2011 and posted on Apr 21, 2011.
- Applicants must submit their applications by Jun 8, 2011. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $3,600,000.00 to eligible and selected applicants.
- The number of recipients for this funding is limited to 5 candidate(s).
- Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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Opportunity Summary:
The DoD FY11 Prostate Cancer Health Disparity Research Award (HDRA) is a funding opportunity under the Department of Defense Prostate Cancer Research Program (PCRP) designed to support innovative research that helps explain, reduce, and ultimately eliminate disparities in prostate cancer incidence, illness burden, and death rates. The award mechanism has been in place since FY01 and, as of this announcement, had attracted 177 applications with 45 recommended for funding, reflecting a competitive program with a clear emphasis on impactful, disparity-focused work. The central expectation is that proposed studies will advance understanding of why certain populations experience worse prostate cancer outcomes and will generate knowledge that can contribute meaningfully to closing those gaps.
A key requirement is that applicants explicitly connect their project to at least one prostate cancer health disparity area. The announcement highlights several examples of appropriate disparity dimensions, including race and ethnicity, socioeconomic status, access to health care, insurance status, age, geography, and cultural beliefs, while also allowing other well-justified disparity factors. The program is open to a wide range of research along the basic-to-clinical spectrum, as long as the core focus remains a health disparity issue in prostate cancer. In addition to the disparity focus, projects should align with at least one PCRP focus area and are encouraged (but not required) to address one of the PCRP overarching challenges.
Human subjects research is allowed, but clinical trials are not permitted under this mechanism. The solicitation uses a standard definition of a clinical trial: prospective enrollment of human subjects to test an intervention (such as a drug, device, biologic, surgery, behavioral program, or similar) for measurable outcomes related to safety, effectiveness, or efficacy. Applicants whose work would qualify as a clinical trial are directed instead to the FY11 PCRP Clinical Trial Award. Likewise, investigators planning population-based studies are encouraged to consider the FY11 PCRP Population Based Research Award, with the important rule that each research project can only be submitted to one award mechanism.
The HDRA also offers two optional pathways that applicants can use to strengthen competitiveness or access different funding considerations. First, the Qualified Collaborator Option is aimed at projects where success depends on a substantial collaboration, such as partnerships between basic and clinical researchers, collaborations bridging prostate cancer expertise and health disparity expertise, or research teams working closely with community organizations tied to disproportionately affected populations. To qualify, the application must include a Qualified Collaboration Statement and a collaborator letter, and it must show that the collaborator provides essential intellectual input and tangible resources (for example, data access, tissue, equipment, personnel, services, or patient access). The collaborator must contribute at least 10 percent level of effort, and this commitment should be reflected in the budget. If the principal investigator lacks experience in prostate cancer research or in working with disproportionately affected groups, the collaborator is expected to bring that experience.
Second, the New Investigator Option is intended for early-career researchers who are still establishing independence. Under this option, New Investigator applications are reviewed separately from those submitted by established investigators, which can help level the playing field. Even so, the announcement encourages New Investigators to build strong teams by involving experienced prostate cancer researchers and/or other experts with relevant track records in funding and publications, and to clearly explain how these team members fill expertise gaps and strengthen the approach. Applicants are allowed to use both the New Investigator Option and the Qualified Collaborator Option in the same submission, as long as eligibility requirements are met.
Administratively, this opportunity was posted April 21, 2011, with an original and current closing date of June 8, 2011, and an archive date of July 8, 2011. It is offered by the Department of the Army (USAMRAA) under Funding Opportunity Number W81XWH-11-PCRP-HDR A, listed under CFDA 12.420 (Military Medical Research and Development). The instrument type includes grants and cooperative agreements, cost sharing is not required, eligibility is described as unrestricted (open to any entity type, subject to any clarifications in the full text), and the program anticipated approximately five awards with an estimated total funding level of $3.6 million. For technical access issues, applicants were directed to the CDMRP Help Desk at 301-682-5507, and the announcement references a Human Subject Resource Document available through the CDMRP program announcements and forms page.
Frequently Asked Questions (FAQs): DoD FY11 Prostate Cancer Health Disparity Research Award (HDRA)
1. What is the DoD FY11 Prostate Cancer Health Disparity Research Award (HDRA)?
The HDRA is a funding opportunity under the Department of Defense (DoD) Prostate Cancer Research Program (PCRP) that supports innovative research intended to explain, reduce, and ultimately eliminate disparities in prostate cancer incidence, illness burden, and death rates.
2. What is the main goal or expectation of an HDRA project?
The central expectation is that the proposed study advances understanding of why certain populations experience worse prostate cancer outcomes and generates knowledge that can contribute meaningfully to closing those gaps.
3. How competitive is this award mechanism?
As of this announcement, the mechanism had attracted 177 applications and 45 were recommended for funding, indicating a competitive program with a strong emphasis on impactful, disparity-focused work.
4. What types of disparities must an application address?
Applicants must explicitly connect their project to at least one prostate cancer health disparity area. Examples listed include race and ethnicity, socioeconomic status, access to health care, insurance status, age, geography, and cultural beliefs. Other disparity factors may be acceptable if well justified.
5. Does the research have to be basic science, clinical, or something else?
The program is open to a wide range of research across the basic-to-clinical spectrum, as long as the core focus remains a health disparity issue in prostate cancer.
6. Do projects have to align with other PCRP priorities beyond health disparities?
Yes. In addition to a clear health disparity focus, projects should align with at least one PCRP focus area. Applicants are also encouraged (but not required) to address one of the PCRP overarching challenges.
7. Are human subjects allowed in this award?
Yes. Human subjects research is allowed under this mechanism.
8. Are clinical trials allowed under the HDRA?
No. Clinical trials are not permitted under this award mechanism.
9. How does the solicitation define a clinical trial?
A clinical trial is defined as prospective enrollment of human subjects to test an intervention (for example, a drug, device, biologic, surgery, behavioral program, or similar) for measurable outcomes related to safety, effectiveness, or efficacy.
10. Where should applicants apply if their project is a clinical trial?
Applicants whose work would qualify as a clinical trial are directed to apply to the FY11 PCRP Clinical Trial Award instead of the HDRA.
11. What if the proposed work is population-based research?
Investigators planning population-based studies are encouraged to consider the FY11 PCRP Population Based Research Award.
12. Can the same research project be submitted to more than one PCRP award mechanism?
No. Each research project can only be submitted to one award mechanism.
13. What is the Qualified Collaborator Option?
The Qualified Collaborator Option is an optional pathway intended for projects where success depends on substantial collaboration. Examples include partnerships between basic and clinical researchers, collaborations bridging prostate cancer expertise and health disparity expertise, or teams working closely with community organizations tied to disproportionately affected populations.
14. What documentation is required to use the Qualified Collaborator Option?
The application must include a Qualified Collaboration Statement and a collaborator letter.
15. What makes a collaborator "qualified" under this option?
The application must demonstrate that the collaborator provides essential intellectual input and tangible resources (such as data access, tissue, equipment, personnel, services, or patient access).
16. Is there a minimum effort requirement for the Qualified Collaborator?
Yes. The collaborator must contribute at least a 10 percent level of effort, and that commitment should be reflected in the budget.
17. What if the principal investigator (PI) lacks experience in prostate cancer research or working with disproportionately affected groups?
If the PI lacks experience in prostate cancer research or in working with disproportionately affected groups, the collaborator is expected to bring that experience.
18. What is the New Investigator Option?
The New Investigator Option is an optional pathway intended for early-career researchers who are still establishing independence. Under this option, New Investigator applications are reviewed separately from those submitted by established investigators.
19. Does using the New Investigator Option guarantee funding or remove expectations for a strong team?
No. While New Investigator applications are reviewed separately, the announcement encourages New Investigators to build strong teams by involving experienced prostate cancer researchers and/or other experts with strong track records in funding and publications, and to explain how these members fill expertise gaps and strengthen the approach.
20. Can an applicant use both the New Investigator Option and the Qualified Collaborator Option?
Yes. Applicants may use both options in the same submission as long as eligibility requirements are met.
21. Who is the awarding agency and administering organization for this opportunity?
The opportunity is offered by the Department of the Army (USAMRAA) under the DoD PCRP.
22. What is the Funding Opportunity Number (FON) for this announcement?
The Funding Opportunity Number is W81XWH-11-PCRP-HDRA.
23. What CFDA number is associated with this opportunity?
The announcement is listed under CFDA 12.420, Military Medical Research and Development.
24. What type of funding instrument is used?
The instrument type includes grants and cooperative agreements.
25. Is cost sharing or matching required?
No. Cost sharing is not required.
26. Who is eligible to apply?
Eligibility is described as unrestricted (open to any entity type), subject to any clarifications in the full text of the announcement.
27. Approximately how many awards and how much funding were anticipated?
The program anticipated approximately five awards, with an estimated total funding level of $3.6 million.
28. What were the key dates for this opportunity?
The opportunity was posted on April 21, 2011. The original and current closing date was June 8, 2011. The archive date was July 8, 2011.
29. Where can applicants get help with technical access issues?
For technical access issues, applicants were directed to the CDMRP Help Desk at 301-682-5507.
30. Is there any referenced resource for human subjects requirements?
Yes. The announcement references a Human Subject Resource Document available through the CDMRP program announcements and forms page.
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