Opportunity Information: Apply for W81XWH 12 DMDRP IIRA
Apply for W81XWH 12 DMDRP IIRA
- The Dept. of the Army USAMRAA in the science and technology and other research and development sector is offering a public funding opportunity titled "DOD FY12 Duchenne Muscular Dystrophy Investigator Initiated Research Award" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 12.420 Military Medical Research and Development.
- This funding opportunity was created on Jun 6, 2012 and posted on Jun 6, 2012.
- Applicants must submit their applications by Nov 7, 2012. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $2,020,000.00 to eligible and selected applicants.
- The number of recipients for this funding is limited to 2 candidate(s).
- Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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Opportunity Summary:
The DOD FY12 Duchenne Muscular Dystrophy (DMD) Investigator Initiated Research Award (IIRA) is a Department of Defense funding opportunity under the FY12 Duchenne Muscular Dystrophy Research Program (DMDRP), managed through the U.S. Army Medical Research Acquisition Activity (USAMRAA). Its overall aim aligns with the program vision: to extend and improve function, quality of life, and lifespan for people living with DMD. In practical terms, the award is meant to push forward research that helps move promising DMD ideas toward real-world clinical use, while also strengthening the field's understanding of why certain therapeutic approaches succeed or fail when tested in patients.
This award specifically targets investigator-initiated, translational research projects that can make a meaningful contribution to understanding how DMD begins and progresses and/or how patient care can be improved. The emphasis is on work that accelerates development and clinical testing of new therapeutics, even though the award itself does not pay for running a clinical trial. That said, it can support correlative or companion studies tied to an existing clinical trial, as well as efforts aimed at developing or refining clinical trial endpoints, which are often a major bottleneck in rare disease drug development. The scope is broad enough to include preclinical studies using animal models, studies involving human subjects (when not constituting a full clinical trial), and research using human anatomical substances, reflecting a clear interest in bridging basic discoveries and clinically actionable results.
From an administrative and funding standpoint, this opportunity was offered as either a grant or a cooperative agreement under the Science and Technology and other Research and Development category. The expected number of awards was two, with an estimated total funding pool of about $2,020,000. There was no cost sharing or matching requirement, which typically lowers barriers for applicants who may not have access to institutional matching funds. Eligibility was described as unrestricted, meaning it was broadly open to applicant organizations, subject to any additional eligibility clarifications contained in the full announcement.
Key dates for the original posting show it was made available on June 6, 2012, with an application deadline of November 7, 2012, and an archive date of December 7, 2012. The funding opportunity number was W81XWH 12 DMDRP IIRA, and it was associated with CFDA 12.420 (Military Medical Research and Development). For applicant support and technical issues related to accessing the full announcement or using the submission systems, the contact listed was the CDMRP Help Desk (PA HELP and eReceipt HELP) at 301-682-5507 and help@cdmrp.org.
FAQs: DOD FY12 Duchenne Muscular Dystrophy (DMD) Investigator Initiated Research Award (IIRA)
What is the DOD FY12 DMD Investigator Initiated Research Award (IIRA)?
The DOD FY12 Duchenne Muscular Dystrophy (DMD) Investigator Initiated Research Award (IIRA) is a Department of Defense funding opportunity offered under the FY12 Duchenne Muscular Dystrophy Research Program (DMDRP). It is managed through the U.S. Army Medical Research Acquisition Activity (USAMRAA).
What is the main goal of this award?
The overall aim aligns with the DMDRP vision: to extend and improve function, quality of life, and lifespan for people living with Duchenne Muscular Dystrophy (DMD). In practical terms, it is intended to advance research that moves promising DMD ideas closer to clinical use and improves understanding of why therapeutic approaches may succeed or fail in patients.
What type of research projects does this award support?
This award targets investigator-initiated, translational research projects that make a meaningful contribution to understanding how DMD begins and progresses and/or how patient care can be improved. It emphasizes work that accelerates development and clinical testing of new therapeutics, while also supporting research that helps interpret clinical outcomes (including why certain approaches work or do not work in patients).
Does this award fund clinical trials?
No. The award emphasizes accelerating development and clinical testing of new therapeutics, but it does not pay for running a clinical trial.
Can the award support studies connected to an existing clinical trial?
Yes. It can support correlative or companion studies tied to an existing clinical trial.
Can the award support work on clinical trial endpoints?
Yes. The opportunity specifically allows efforts aimed at developing or refining clinical trial endpoints, recognizing endpoints as a major bottleneck in rare disease drug development.
Are preclinical studies allowed?
Yes. The scope includes preclinical studies using animal models.
Are studies involving human subjects allowed?
Yes. Studies involving human subjects are included in scope, as long as they do not constitute a full clinical trial.
Is research using human anatomical substances allowed?
Yes. Research using human anatomical substances is within scope, reflecting an emphasis on bridging basic discoveries and clinically actionable results.
Who manages this funding opportunity?
The opportunity is managed through the U.S. Army Medical Research Acquisition Activity (USAMRAA) under the FY12 DMDRP.
What funding mechanism was used for this opportunity?
This opportunity was offered as either a grant or a cooperative agreement under the Science and Technology and other Research and Development category.
How many awards were expected to be made?
The expected number of awards was two.
What was the estimated total funding available?
The estimated total funding pool was about $2,020,000.
Is cost sharing or matching required?
No. There was no cost sharing or matching requirement.
Who was eligible to apply?
Eligibility was described as unrestricted, meaning it was broadly open to applicant organizations, subject to any additional eligibility clarifications contained in the full announcement.
What is the funding opportunity number?
The funding opportunity number was W81XWH 12 DMDRP IIRA.
What CFDA number is associated with this opportunity?
This opportunity was associated with CFDA 12.420 (Military Medical Research and Development).
When was the opportunity posted?
The original posting date was June 6, 2012.
What was the application deadline?
The application deadline was November 7, 2012.
When was the opportunity archived?
The archive date was December 7, 2012.
Where can applicants get help with technical or submission issues?
For support accessing the full announcement or using the submission systems, applicants could contact the CDMRP Help Desk (PA HELP and eReceipt HELP) at 301-682-5507 or help@cdmrp.org.
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