DoD FY13 CRMRP VRP Hypothesis Development Award | Apply Online

Opportunity Summary:

The DoD FY13 CRMRP Vision Research Program (VRP) Hypothesis Development Award (HDA) is a Department of Defense funding opportunity run through the U.S. Army Medical Research Acquisition Activity (USAMRAA) under CFDA 12.420 (Military Medical Research and Development). It is designed specifically to push the vision research field forward by backing conceptually innovative, high risk/high reward projects that can open up new directions or lead to major breakthroughs rather than simply adding another incremental step to an existing line of work. The central expectation is that proposed studies will be built around a clearly testable hypothesis supported by a strong scientific rationale, even if the idea is early-stage and not yet heavily validated.

A key feature of this award is its emphasis on impact and originality. Applications are expected to aim for an important and genuinely new contribution to understanding visual dysfunction, with a clear line of sight to how the knowledge gained could ultimately improve outcomes for patients, including service members and veterans affected by trauma-related visual injury. The program is not meant to fund routine follow-on experiments, the continuation of ongoing studies, or the next logical extension of already published work. Instead, it favors proposals that could produce influential data, reveal previously unrecognized mechanisms, or generate entirely new avenues of investigation in vision science and rehabilitation.

Innovation is the defining criterion. The DoD frames innovation broadly, so it can include introducing a new paradigm, challenging established assumptions, approaching a long-standing problem from a different perspective, or applying uniquely creative approaches. Innovation may be expressed through the core concept, the experimental design, the use of new methods or technologies, or novel adaptations of existing tools. While preliminary or published data relevant to the program focus areas is encouraged, it is explicitly not required, which is consistent with the goal of enabling earlier, riskier ideas. At the same time, applicants are expected to do the work of clearly explaining what makes the project innovative and why it is not incremental compared to existing literature.

To be considered responsive, every application must directly address at least one of the FY13 VRP HDA focus areas. These focus areas concentrate on trauma and warfighter-relevant vision problems and include: (1) mitigation and treatment of traumatic injuries, war-related injuries, and diseases affecting ocular structures and the visual system; (2) mitigation and treatment of visual dysfunction associated with traumatic brain injury (TBI); (3) vision restoration following traumatic injury; and (4) modeling and simulation of traumatic ocular injury. Proposals outside these defined areas are considered nonresponsive and should not be submitted under this announcement.

From an administrative and funding standpoint, the opportunity was posted on October 28, 2013, with an original and final closing date of February 6, 2014, and an archive date of March 8, 2014. The total estimated funding listed is $2.5 million, with an anticipated 10 awards. Funding instruments include grants and cooperative agreements, and there is no cost sharing or matching requirement. Eligibility is listed as unrestricted, meaning a wide range of entity types could apply as long as they meet any specific eligibility clarifications contained in the full announcement. For assistance accessing the announcement, the CDMRP Help Desk was provided as a point of contact at 301-682-5507.

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