Opportunity Information: Apply for W81XWH 15 JPC 8 CRMRP NMSIRA
Apply for W81XWH 15 JPC 8 CRMRP NMSIRA
- The Dept. of the Army USAMRAA in the science and technology and other research and development sector is offering a public funding opportunity titled "DoD FY15 Neuromusculoskeletal Injuries Award" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 12.420 Military Medical Research and Development.
- This funding opportunity was created on Apr 28, 2015 and posted on Apr 28, 2015.
- Applicants must submit their applications by Aug 17, 2015. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $7,150,000.00 to eligible and selected applicants.
- The number of recipients for this funding is limited to 5 candidate(s).
- Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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Opportunity Summary:
The DoD FY15 Neuromusculoskeletal Injuries Research Award (NMSIRA), offered through the Department of the Army under the Congressionally Directed Medical Research Programs (CDMRP) and Joint Program Committee 8 (JPC-8), was a competitive research funding opportunity aimed at improving outcomes for people with neuromusculoskeletal injuries, particularly in military-relevant contexts. The program was designed to fund both preclinical research and clinical trials that can move the field toward practical, patient-centered solutions. The central idea is to help injured individuals recover function and quality of life in the real world by advancing rehabilitation approaches, improving assistive technologies (like prosthetics and orthotics), understanding and preventing downstream health complications after severe limb injury, and strengthening how clinicians choose and prescribe devices and therapies over the course of recovery.
A core requirement of this opportunity was tight alignment with the program's specified Focus Areas. Applications were expected to directly address at least one of those stated needs; proposals that fell outside these areas were discouraged from submission. In practice, this meant the program was not looking for general musculoskeletal or rehabilitation research unless it clearly mapped to the defined gaps around reintegration, device function and human-device interface challenges, secondary health effects, rehabilitation sequencing and dosing, or better measurement and assessment tools.
One major Focus Area emphasized physical and psychosocial reintegration after neuromusculoskeletal injury. The announcement highlights that current capabilities are limited when it comes to assessing and supporting a return to meaningful life roles, community participation, and overall well-being after injury. Specific needs included stronger social support strategies, more innovative technologies that improve interconnectivity (for example, tools that help connect patients with clinicians, caregivers, or peer support networks), and methods or technologies that promote lifelong wellness and quality of life rather than just short-term clinical gains. It also called out the need for validated approaches that measure and facilitate return to real-world functional performance, reflecting an emphasis on outcomes that matter outside the clinic.
Another major Focus Area targeted limitations in assistive technology, particularly issues that affect day-to-day usability, comfort, and durability of prosthetic and orthotic systems. The program identified gaps such as insufficient proprioceptive or other sensory inputs that can reduce safety and effective use, the lack of intuitive user-intent control (meaning that devices may not respond naturally to what the user is trying to do), and poor interoperability between device components. Interoperability was framed as a barrier to realizing the full potential of multi-joint systems, especially as new components are developed and users need flexible combinations over time. The human-device interface itself was also a priority, including challenges related to limb health, comfort, and overall function, which can determine whether a device is used consistently or abandoned.
The opportunity also prioritized research on secondary health effects that can emerge after the initial injury, recognizing that severe extremity injuries often lead to additional long-term conditions that can be debilitating and costly. The program sought studies that improve the ability to predict, identify, and reduce these secondary effects. Examples listed included osteoarthritis, low back pain, and other musculoskeletal conditions, with an emphasis on understanding what factors predict who develops these problems and what treatments are most successful. It also highlighted limited intervention strategies to reduce fall risk and fracture risk, as well as limited strategies to prevent chronic comorbidities such as obesity, cardiovascular disease, and diabetes, which can be exacerbated by reduced mobility, altered biomechanics, and activity limitations after injury.
A further Focus Area addressed the need for better evidence on optimal rehabilitation strategies and the sequence of progression throughout the rehabilitation process, explicitly including common injuries like sprains and strains. The program noted that evidence is often inadequate to determine basic but critical parameters of care such as the best dose, timing, frequency, duration, and setting for rehabilitation, including how and when to incorporate innovative rehabilitative techniques. The intent here was to support work that can guide clinicians toward approaches that minimize impairment, maximize function and performance, and improve quality of life, rather than relying on tradition or inconsistent practice patterns.
The final key Focus Area centered on measurement: the lack of adequate standardized assessments of activity performance and participation, and the shortage of validated metrics that can predict function after neuromusculoskeletal injury. The announcement also pointed to a limited number of validated tools that can quantify meaningful change due to rehabilitation or new technologies, and the absence of objective, functional standards for discharge from clinical care. This theme reflects a broader need in rehabilitation science: without strong measurement tools, it is hard to compare interventions, tailor care, or prove that new devices or programs deliver real-world benefits.
From an administrative and funding standpoint, this was a discretionary DoD research and development opportunity (CFDA 12.420, Military Medical Research and Development) with an estimated total funding amount of $7,150,000 and an expectation of around five awards. It allowed for funding through grants and cooperative agreements, did not require cost sharing or matching, and listed eligibility as unrestricted, meaning a wide range of organizations could apply subject to any clarifications in the full announcement. The opportunity was posted on April 28, 2015, with an original and final closing date of August 17, 2015, and it was later archived on September 16, 2015. The sponsoring agency was the Department of the Army, with USAMRAA referenced in the listing, and applicants needing help accessing the full announcement were directed to the CDMRP Help Desk (301-682-5507).
Frequently Asked Questions (FAQs)
What is the DoD FY15 Neuromusculoskeletal Injuries Research Award (NMSIRA)?
The DoD FY15 Neuromusculoskeletal Injuries Research Award (NMSIRA) was a competitive Department of Defense research funding opportunity offered through the Department of the Army under the Congressionally Directed Medical Research Programs (CDMRP) and Joint Program Committee 8 (JPC-8). It was intended to support research that improves outcomes for people with neuromusculoskeletal injuries, particularly in military-relevant contexts.
What types of research did this award support?
The program was designed to fund both preclinical research and clinical trials. The emphasis was on work that moves toward practical, patient-centered solutions that improve real-world function and quality of life, including rehabilitation approaches, assistive technology advances (such as prosthetics and orthotics), and strategies to address longer-term health complications following severe limb injury.
What was the overall goal or central idea behind this funding opportunity?
The central aim was to help injured individuals recover function and quality of life in day-to-day life by advancing rehabilitation, improving assistive technologies, understanding and preventing downstream health complications, and strengthening how clinicians choose and prescribe devices and therapies over the course of recovery.
Did applications have to align with specific Focus Areas?
Yes. A core requirement was tight alignment with the program's specified Focus Areas. Applications were expected to directly address at least one stated Focus Area need, and proposals outside these areas were discouraged from submission.
Would general musculoskeletal or general rehabilitation research have been a fit?
Not necessarily. The opportunity was not looking for broad musculoskeletal or rehabilitation research unless it clearly mapped to defined gaps such as reintegration, device function and human-device interface challenges, secondary health effects, rehabilitation sequencing and dosing, or improved measurement and assessment tools.
What Focus Area addressed reintegration after injury?
One major Focus Area emphasized physical and psychosocial reintegration after neuromusculoskeletal injury. It highlighted limitations in assessing and supporting return to meaningful life roles, community participation, and overall well-being after injury.
What kinds of reintegration needs were highlighted?
Specific needs included stronger social support strategies, innovative technologies that improve interconnectivity (for example, tools that help connect patients with clinicians, caregivers, or peer support networks), and methods or technologies that promote lifelong wellness and quality of life rather than only short-term clinical gains.
Was real-world functional performance emphasized over in-clinic outcomes?
Yes. The program called for validated approaches that measure and facilitate return to real-world functional performance, reflecting an emphasis on outcomes that matter outside the clinic.
What Focus Area addressed assistive technology such as prosthetics and orthotics?
Another major Focus Area targeted limitations in assistive technology affecting day-to-day usability, comfort, and durability of prosthetic and orthotic systems.
What specific assistive technology gaps were identified?
Identified gaps included insufficient proprioceptive or other sensory inputs (which can reduce safety and effective use), lack of intuitive user-intent control (devices not responding naturally to what the user is trying to do), and poor interoperability between device components.
Why was interoperability between device components important in this opportunity?
Interoperability was framed as a barrier to realizing the full potential of multi-joint systems. As new components are developed and users need flexible combinations over time, poor interoperability can limit performance and long-term adaptability.
What is meant by the "human-device interface" and why was it a priority?
The human-device interface refers to the points and ways the user and device interact (including fit, comfort, limb health considerations, and functional control). It was a priority because interface problems can strongly influence comfort, overall function, and whether a device is used consistently or abandoned.
What Focus Area addressed secondary health effects after severe extremity injuries?
The opportunity prioritized research on secondary health effects that can emerge after the initial injury, recognizing that severe extremity injuries often lead to additional long-term conditions that can be debilitating and costly.
What kinds of secondary health effects were mentioned as examples?
Examples included osteoarthritis, low back pain, and other musculoskeletal conditions. The program emphasized understanding which factors predict who develops these problems and identifying the most successful treatments.
Did the opportunity mention fall risk, fracture risk, or chronic comorbidities?
Yes. It noted limited intervention strategies to reduce fall risk and fracture risk, and limited strategies to prevent chronic comorbidities such as obesity, cardiovascular disease, and diabetes that may be exacerbated by reduced mobility, altered biomechanics, and activity limitations after injury.
What Focus Area addressed rehabilitation strategies and how care is progressed?
A further Focus Area addressed the need for better evidence on optimal rehabilitation strategies and the sequence of progression throughout the rehabilitation process, explicitly including common injuries like sprains and strains.
What rehabilitation parameters did the program identify as needing stronger evidence?
The program noted that evidence is often inadequate to determine key parameters such as the best dose, timing, frequency, duration, and setting for rehabilitation, including how and when to incorporate innovative rehabilitative techniques.
What was the intent of funding work on rehabilitation sequencing and dosing?
The intent was to support work that guides clinicians toward approaches that minimize impairment, maximize function and performance, and improve quality of life, rather than relying on tradition or inconsistent practice patterns.
What Focus Area addressed measurement and assessment tools?
The final key Focus Area centered on measurement, including the lack of adequate standardized assessments of activity performance and participation, and the shortage of validated metrics that can predict function after neuromusculoskeletal injury.
What measurement-related gaps were specifically noted?
The announcement pointed to a limited number of validated tools that can quantify meaningful change due to rehabilitation or new technologies, and the absence of objective, functional standards for discharge from clinical care.
Why does the opportunity place emphasis on measurement tools?
The information provided indicates that without strong measurement tools, it is difficult to compare interventions, tailor care, or demonstrate that new devices or programs deliver real-world benefits.
What agency and program components sponsored or managed this opportunity?
The sponsoring agency was the Department of the Army. The opportunity was offered through CDMRP and JPC-8, and USAMRAA was referenced in the listing.
What was the CFDA number and program category for this opportunity?
The opportunity was listed as a discretionary DoD research and development opportunity under CFDA 12.420, Military Medical Research and Development.
How much total funding was estimated, and how many awards were expected?
The estimated total funding amount was $7,150,000, with an expectation of around five awards.
What award mechanisms were available?
Funding could be provided through grants and cooperative agreements.
Was cost sharing or matching required?
No. The opportunity did not require cost sharing or matching.
Who was eligible to apply?
Eligibility was listed as unrestricted, meaning a wide range of organizations could apply, subject to any clarifications provided in the full announcement.
When was the opportunity posted, and what were the closing dates?
The opportunity was posted on April 28, 2015. The original and final closing date was August 17, 2015.
Was this opportunity archived?
Yes. It was later archived on September 16, 2015.
Where could applicants get help accessing the full announcement?
Applicants needing help accessing the full announcement were directed to the CDMRP Help Desk at 301-682-5507.
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