Opportunity Information: Apply for W81XWH 15 OPORP PORA

  • The Dept. of the Army USAMRAA in the science and technology and other research and development sector is offering a public funding opportunity titled "DoD FY15 Prosthetics Outcomes Research Award" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 12.420 Military Medical Research and Development.
  • This funding opportunity was created on Jul 20, 2015 and posted on Jul 16, 2015.
  • Applicants must submit their applications by Nov 16, 2015. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $4,500,000.00 to eligible and selected applicants.
  • The number of recipients for this funding is limited to 6 candidate(s).
  • Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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Opportunity Summary:

The DoD FY15 Prosthetics Outcomes Research Award (PORA) is a Department of Defense funding opportunity designed to build practical, evidence-based knowledge about what prosthetic-related care works best for injured Service members and Veterans. The program focuses on comparative effectiveness research, meaning it supports studies that directly compare prosthetic devices, clinical approaches, and rehabilitation strategies to see which options lead to better real-world results. A central requirement is that projects rely on patient-centric outcomes, so success is measured in terms that matter to the person using the prosthesis (function, comfort, daily performance, quality of life, reintegration, and similar outcomes), not just technical performance or lab-based metrics. The intent is to improve understanding of prosthetic devices and care pathways, including secondary health effects tied to prosthesis use, and to move findings into routine practice so that effective interventions are adopted and implemented more widely.

Projects proposed under this award are expected to produce outcomes data that can meaningfully influence clinical decision-making and patient care metrics. In other words, applicants need to show how the research results could change what clinicians prescribe, how rehabilitation is delivered, or how patients are managed over time, and what measurable improvements might follow. The announcement encourages studies that track people longitudinally (following patients across multiple time points), compare different approaches to care, and incorporate patient-centered assessment tools. A major emphasis is on generating actionable evidence that can support the creation of new clinical practice guidelines, refine existing guidelines and recommendations, and inform new prescription algorithms that help providers match the right prosthetic device and care plan to the right patient at the right time.

The scope is broad as long as the work stays clearly connected to prosthetic use in the context of traumatic extremity injury and/or amputation among Service members and Veterans. Example topics include determining when in the treatment timeline a prosthetic intervention is most effective, comparing different treatment algorithms used to select a device, evaluating the comparative effectiveness of different prosthetic devices, studying ways to prevent secondary adverse consequences associated with prosthesis use, and testing rehabilitation interventions that could speed up or improve functional recovery. The program also values outputs that translate directly to the clinic and patient use, such as decision tools, protocols, and evidence that can be readily implemented by care teams. Collaboration is strongly encouraged, particularly efforts that align with or integrate Department of Defense and/or VA research laboratories and programs, reflecting the program goal of producing findings that fit the military and Veteran health system contexts.

Administratively, the opportunity was released by the Department of the Army, U.S. Army Medical Research Acquisition Activity (USAMRAA), under Funding Opportunity Number W81XWH-15-OPORP-PORA, within the broader category of military medical research and development (CFDA 12.420). The funding instrument types listed include grants and cooperative agreements, with an estimated total funding amount of $4.5 million and an expectation of about six awards. Eligibility was described as unrestricted (open to any type of entity, subject to any specific clarifications in the full announcement), and there was no cost-sharing or matching requirement. Key dates in the posted information include a posted date of July 16, 2015, and a closing date of November 16, 2015 (with the listing later archived). For help accessing the full announcement, the contact provided is the CDMRP Help Desk (301-682-5507, help@eBRAP.org).

DoD FY15 Prosthetics Outcomes Research Award (PORA) - FAQs

1) What is the DoD FY15 Prosthetics Outcomes Research Award (PORA)?

The FY15 Prosthetics Outcomes Research Award (PORA) is a Department of Defense funding opportunity focused on building practical, evidence-based knowledge about what prosthetic-related care works best for injured Service members and Veterans. The goal is to generate outcomes data that can improve real-world patient care and influence clinical decision-making.

2) What is the main purpose of this funding opportunity?

The main purpose is to support research that compares prosthetic devices, clinical approaches, and rehabilitation strategies to determine which options lead to better outcomes for prosthesis users. The program aims to move findings into routine practice so effective interventions are adopted more widely.

3) What kind of research does PORA prioritize?

PORA prioritizes comparative effectiveness research. That means studies should directly compare two or more prosthetic-related options (devices, care pathways, rehabilitation approaches, or treatment algorithms) and evaluate which works best in real-world settings.

4) What does "patient-centric outcomes" mean in this program?

Patient-centric outcomes means success is measured using outcomes that matter to the person using the prosthesis, such as function, comfort, daily performance, quality of life, reintegration, and similar user-centered outcomes. The program emphasizes these outcomes over purely technical performance or lab-only metrics.

5) What types of outcomes are expected from funded projects?

Projects are expected to produce outcomes data that can meaningfully influence clinical decision-making and patient care metrics. Applicants are expected to show how results could change prosthetic prescriptions, rehabilitation delivery, or long-term patient management, and what measurable improvements could follow.

6) Is there an expectation that findings will be used in clinical practice?

Yes. A key intent is translating results into routine practice. The program emphasizes actionable evidence and outputs that can be adopted by care teams, including decision tools, protocols, and evidence that can be readily implemented in military and Veteran health system settings.

7) Are longitudinal studies encouraged?

Yes. The announcement encourages studies that track people longitudinally, meaning patients are followed across multiple time points to understand outcomes over time.

8) Can you give examples of research topics that fit the scope?

Example topics mentioned include:

  • Determining when in the treatment timeline a prosthetic intervention is most effective
  • Comparing different treatment algorithms used to select a prosthetic device
  • Evaluating the comparative effectiveness of different prosthetic devices
  • Studying ways to prevent secondary adverse consequences associated with prosthesis use
  • Testing rehabilitation interventions that could speed up or improve functional recovery

9) What population or clinical context is this award meant to address?

The scope is tied to prosthetic use in the context of traumatic extremity injury and/or amputation among Service members and Veterans. Projects should stay clearly connected to that population and use context.

10) Are secondary health effects related to prosthesis use within scope?

Yes. The program specifically notes interest in improving understanding of prosthetic devices and care pathways, including secondary health effects tied to prosthesis use, as well as preventing secondary adverse consequences.

11) Does PORA support work related to clinical practice guidelines?

Yes. A major emphasis is on generating actionable evidence that can support creating new clinical practice guidelines, refining existing guidelines and recommendations, and informing new prescription algorithms that help match the right prosthetic device and care plan to the right patient at the right time.

12) What kinds of deliverables or outputs are valued?

Outputs that translate directly to clinic and patient use are valued, including decision tools, protocols, and evidence that can be readily implemented by care teams.

13) Is collaboration required or encouraged?

Collaboration is strongly encouraged, especially efforts that align with or integrate Department of Defense and/or VA research laboratories and programs. This reflects the goal of producing findings that fit military and Veteran health system contexts.

14) Which agency released this opportunity?

The opportunity was released by the Department of the Army, U.S. Army Medical Research Acquisition Activity (USAMRAA).

15) What is the funding opportunity number for this award?

The Funding Opportunity Number is W81XWH-15-OPORP-PORA.

16) What CFDA program is this associated with?

It is listed under CFDA 12.420, within the broader category of military medical research and development.

17) What funding instrument types are available?

The listed funding instrument types include grants and cooperative agreements.

18) How much total funding was estimated for this opportunity?

The estimated total funding amount was $4.5 million.

19) How many awards were expected to be made?

The opportunity anticipated about six awards.

20) Who was eligible to apply?

Eligibility was described as unrestricted, meaning it was open to any type of entity, subject to any specific clarifications in the full announcement.

21) Was cost-sharing or matching required?

No. The posted information states there was no cost-sharing or matching requirement.

22) When was the opportunity posted and when did it close?

The posted date was July 16, 2015, and the closing date was November 16, 2015. The listing was later archived.

23) Who can be contacted for help accessing the full announcement?

For help accessing the full announcement, the contact provided is the CDMRP Help Desk at 301-682-5507 or help@eBRAP.org.

24) What should applicants emphasize to show their project is a good fit?

Based on the description, applicants would be expected to emphasize comparative effectiveness, patient-centered outcomes, real-world clinical impact, and a clear pathway for findings to influence clinical decision-making, guidelines, prescription algorithms, and routine practice in Service member and Veteran care contexts.

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