Opportunity Information: Apply for W81XWH 15 RTR IDA
Apply for W81XWH 15 RTR IDA
- The Dept. of the Army USAMRAA in the science and technology and other research and development sector is offering a public funding opportunity titled "DoD FY15 Reconstructive Transplant Research (RTR) Idea Discovery Award" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 12.420 Military Medical Research and Development.
- This funding opportunity was created on Jul 23, 2015 and posted on Jul 23, 2015.
- Applicants must submit their applications by Oct 14, 2015. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $2,700,000.00 to eligible and selected applicants.
- The number of recipients for this funding is limited to 6 candidate(s).
- Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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Opportunity Summary:
The DoD FY15 Reconstructive Transplant Research (RTR) Idea Discovery Award is a U.S. Department of Defense funding opportunity run through the Defense Health Agency (DHA) research enterprise and administered by the U.S. Army Medical Research Acquisition Activity (USAMRAA), with management and execution handled by the Congressionally Directed Medical Research Programs (CDMRP). Strategic oversight comes from Joint Program Committee 8 (JPC-8), which covers Clinical and Rehabilitative Medicine Research. In practical terms, this program is part of the Defense Health Program (DHP) research appropriation and is meant to accelerate science that can improve outcomes for patients who need reconstructive transplantation, including vascularized composite allotransplantation (VCA) such as hand or face transplantation and related reconstructive transplant procedures.
This specific mechanism, the RTR Idea Discovery Award (IDA), was offered for the first time in FY15 and is designed to fund early, bold, and genuinely novel research ideas rather than mature projects that are already well underway. The core purpose is to support untested, high-risk and potentially high-reward concepts, whether they are new theories, methods, tools, or ways of thinking about existing problems in reconstructive transplantation. The expectation is not that applicants will already have a fully developed program of work, but that the proposed study will generate strong, robust data that can serve as a credible foundation for future, larger investigations. Applications are expected to be hypothesis-driven, with a clearly formulated and testable hypothesis supported by a solid scientific rationale and a study design that matches the question being asked. The announcement is explicit that incremental extensions of published work or straightforward next steps in an established research line are not the target here and are not considered innovative enough for this award.
To be responsive, proposals must address at least one of the program’s stated focus areas. These include immune system regulation (for example, approaches to reduce or replace long-term immunosuppression, induce tolerance, or manage rejection), improved access to reconstructive transplantation (which can involve barriers to care, logistics, clinical capacity, patient selection, or system-level challenges), reconstructive transplantation rehabilitation (strategies that improve functional recovery, motor and sensory outcomes, and long-term integration of the graft into daily life), graft surveillance and clinical monitoring (methods to detect rejection or complications earlier, track graft health over time, or develop better biomarkers and monitoring technologies), and psychosocial issues associated with VCA (mental health, identity, quality of life, adherence, social reintegration, ethical concerns, and the broader human factors that influence outcomes).
From an administrative standpoint, the opportunity was listed as Funding Opportunity Number W81XWH-15-RTR-IDA and categorized as discretionary funding, with awards issued as cooperative agreements and/or grants under a science and technology research and development activity category. The program anticipated making about six awards with an estimated total funding pool of $2.7 million. It carried no cost sharing or matching requirement, and eligibility was described as unrestricted, meaning applicants from a wide range of organization types could apply, subject to any clarifications in the full announcement text. The posting date was July 23, 2015, and the application deadline was October 14, 2015, with the opportunity later archived on November 13, 2015. The CFDA listing tied to the program was 12.420 (Military Medical Research and Development), reflecting its placement within DoD medical R&D funding.
For applicants seeking help or access to the complete announcement, CDMRP provided a help desk contact (help@cdmrp.org, 301-682-5507). Overall, the RTR IDA is best understood as a seed-funding mechanism meant to spark unconventional but well-reasoned studies that could change how reconstructive transplantation is performed, monitored, rehabilitated, and supported, especially in ways that matter for service members and the broader patient population.
FAQs: DoD FY15 Reconstructive Transplant Research (RTR) Idea Discovery Award (IDA)
What is the DoD FY15 Reconstructive Transplant Research (RTR) Idea Discovery Award (IDA)?
The RTR Idea Discovery Award (IDA) is a U.S. Department of Defense funding mechanism created to support early-stage, bold, and genuinely novel research ideas in reconstructive transplantation, including vascularized composite allotransplantation (VCA) such as hand or face transplantation and related reconstructive transplant procedures.
Which organizations run and administer this funding opportunity?
This opportunity is part of the Defense Health Agency (DHA) research enterprise. It is administered by the U.S. Army Medical Research Acquisition Activity (USAMRAA), with program management and execution handled by the Congressionally Directed Medical Research Programs (CDMRP). Strategic oversight is provided by Joint Program Committee 8 (JPC-8), covering Clinical and Rehabilitative Medicine Research.
What is the overall goal of the program?
The program is intended to accelerate science that improves outcomes for patients who need reconstructive transplantation, including VCA. It is positioned as seed funding to generate robust data that can support future, larger-scale investigations.
What makes the Idea Discovery Award different from other research awards?
The IDA is designed specifically for untested, high-risk and potentially high-reward concepts. It emphasizes early, bold ideas rather than mature projects that are already well underway. Incremental extensions of published work or straightforward next steps in an established research line are explicitly not the target.
Was this award mechanism offered before FY15?
No. The RTR Idea Discovery Award was offered for the first time in FY15.
What kinds of research ideas are encouraged under this award?
The award aims to fund truly novel theories, methods, tools, or approaches to existing problems in reconstructive transplantation. The expectation is that the work will produce strong, credible data that can serve as a foundation for future studies.
Are applications required to be hypothesis-driven?
Yes. Applications are expected to be hypothesis-driven, with a clearly formulated, testable hypothesis supported by a solid scientific rationale and a study design that matches the question being asked.
Does the program expect applicants to already have a fully developed program of work?
No. The program does not expect a fully developed research program at the time of application. It is intended to support early ideas that can generate robust initial data.
What types of proposals are considered non-responsive or not innovative enough?
Incremental extensions of published work or straightforward next steps in an established research line are not the target of this mechanism and are described as not innovative enough for the IDA.
What are the focus areas that a proposal must address to be responsive?
To be responsive, proposals must address at least one of the stated focus areas: immune system regulation; improved access to reconstructive transplantation; reconstructive transplantation rehabilitation; graft surveillance and clinical monitoring; or psychosocial issues associated with VCA.
What does the focus area "immune system regulation" include?
This focus area includes approaches to reduce or replace long-term immunosuppression, induce tolerance, and/or manage rejection in the context of reconstructive transplantation.
What does "improved access to reconstructive transplantation" mean in this program?
It can include barriers to care, logistics, clinical capacity, patient selection, and other system-level challenges that affect the ability of patients to receive reconstructive transplantation.
What topics fall under reconstructive transplantation rehabilitation?
This area includes strategies that improve functional recovery and motor and sensory outcomes, as well as approaches that support long-term integration of the graft into daily life.
What is meant by graft surveillance and clinical monitoring?
This focus area covers methods to detect rejection or complications earlier, track graft health over time, and develop improved biomarkers or monitoring technologies for reconstructive transplantation.
What psychosocial issues associated with VCA are relevant to this opportunity?
Relevant psychosocial topics include mental health, identity, quality of life, adherence, social reintegration, ethical concerns, and other human factors that influence outcomes in VCA.
What is the Funding Opportunity Number for this program?
The Funding Opportunity Number is W81XWH-15-RTR-IDA.
What type of funding is this considered?
It is categorized as discretionary funding.
What award instruments are anticipated for this opportunity?
Awards were expected to be issued as cooperative agreements and/or grants.
What activity category is associated with this funding?
The opportunity is associated with a science and technology research and development activity category.
How many awards were anticipated, and what was the estimated total funding pool?
The program anticipated making about six awards, with an estimated total funding pool of $2.7 million.
Is there a cost sharing or matching requirement?
No. The opportunity stated that there was no cost sharing or matching requirement.
Who is eligible to apply?
Eligibility was described as unrestricted, meaning a wide range of organization types could apply, subject to any clarifications in the full announcement text.
What is the CFDA number associated with this opportunity?
The CFDA listing tied to the program is 12.420, Military Medical Research and Development.
When was the opportunity posted, and what was the application deadline?
The posting date was July 23, 2015, and the application deadline was October 14, 2015.
When was the opportunity archived?
The opportunity was later archived on November 13, 2015.
Where does this funding fit within DoD funding sources?
This program is part of the Defense Health Program (DHP) research appropriation and is aligned with DoD medical research and development priorities in clinical and rehabilitative medicine.
How can applicants get help or obtain the full announcement?
CDMRP provided a help desk for assistance and access to the complete announcement: help@cdmrp.org or 301-682-5507.
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