DoD FY15 Spinal Cord Injury Clinical Trial Award | Apply Online

Opportunity Summary:

The DoD FY15 Spinal Cord Injury Clinical Trial Award (Funding Opportunity Number W81XWH-15-SCIRP-CTA) is a Department of the Army, USAMRAA-administered funding opportunity under the Spinal Cord Injury Research Program (SCIRP) designed specifically to move promising spinal cord injury (SCI) advances into human testing. The central requirement is that proposed work must be a clinical trial involving human subjects, with the intent to produce evidence that could meaningfully change treatment or management of SCI or its downstream complications. Funding from this mechanism is not intended for, and cannot be used to support, preclinical or purely laboratory-based research, which makes it particularly focused on near-term clinical impact and real-world patient outcomes. While the opportunity is rooted in military medical priorities, it explicitly supports research that could benefit military Service members, Veterans, and other individuals living with SCI.

The program highlights three broad topic areas where it is seeking clinical trial proposals. First, it encourages studies aimed at improving the earliest phases of SCI care, including pre-hospital response, en route care, and early hospital management, where time-sensitive decisions can strongly influence neurological outcomes and long-term disability. Second, it emphasizes the development, validation, and optimal timing of interventions that address common and often life-altering consequences of SCI and that support functional recovery. Examples listed in the announcement include bladder, bowel, and autonomic dysfunction; cardiometabolic dysfunction; neuropathic pain and sensory dysfunction; pressure ulcers; respiratory dysfunction; and sexual dysfunction. This focus reflects an understanding that quality of life and long-term medical stability after SCI frequently depend on managing secondary complications as much as on restoring motor function. Third, the award encourages clinical trials that identify and validate best practices across the continuum of SCI care, including critical care interventions, musculoskeletal health interventions, rehabilitation approaches, surgical interventions, and psychosocial or behavioral interventions, with particular attention to applicability in military and Veteran populations.

From an administrative and funding standpoint, the opportunity is categorized as discretionary and supports awards through either cooperative agreements or grants, under the broader federal research and development activity area (Science and Technology and other R&D). The expected number of awards was three, with an estimated total funding amount of $9.6 million, and there was no cost-sharing or matching requirement. Eligibility was listed as unrestricted, meaning applicants were not limited to a narrow set of institution types, though applicants were still expected to follow any clarifications that might appear in the full announcement text. The opportunity was posted on June 2, 2015, and the application deadline was October 14, 2015, with the archive date listed as November 13, 2015. The CFDA number associated with the program is 12.420 (Military Medical Research and Development), which signals its alignment with defense health and readiness needs.

For applicant support, the announcement directs individuals who have trouble accessing the full solicitation to the CDMRP Help Desk, which can be reached by phone at 301-682-5507 or by email at help@eBRAP.org. Overall, this award mechanism is best understood as a targeted DoD investment in clinically testable interventions and care strategies for SCI, prioritizing studies that can generate actionable evidence and improve outcomes for Service members and Veterans while also benefiting the broader SCI community.

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