Opportunity Information: Apply for W81XWH 14 LCRP CEA

The Department of Defense Lung Cancer Research Program (LCRP) offers the Clinical Exploration Award (CEA) aimed at funding early phase clinical trials that test innovative approaches to lung cancer treatment. Launched in Fiscal Year 2013, this program has received multiple applications and recommended a few for funding based on their potential to address significant clinical challenges in lung cancer management.

The CEA supports clinical trials including Phase 0, Phase I, and pilot Phase II studies of drugs, drug combinations, or medical devices. Importantly, while proposals should be novel and hypothesis-driven, they can repurpose existing therapies used for other conditions if they show promise for lung cancer treatment. The goal is to gather enough scientific evidence from these studies to justify larger efficacy trials that could change the landscape of lung cancer care.

Additionally, the CEA includes a new category for correlative studies which examine data from ongoing or completed trials funded by other sources. These studies aim to enhance understanding of lung cancer treatment through areas such as biomarker analysis, drug resistance mechanisms, immune response evaluations, and tumor characterization. Applications in this category are evaluated separately from clinical trial proposals.

Funding is specifically directed towards projects building upon existing clinical trials, not preclinical research. Collaborative efforts, particularly those involving Military Treatment Facilities, military research labs, and the Department of Veterans Affairs, are encouraged to strengthen the impact of the research.

  • The Dept. of the Army USAMRAA in the science and technology and other research and development sector is offering a public funding opportunity titled "DoD Lung Cancer Clinical Exploration Award" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 12.420 Military Medical Research and Development.
  • This funding opportunity was created on Apr 14, 2014 and posted on Apr 14, 2014.
  • Applicants must submit their applications by Sep 17, 2014. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2025.)
  • The funding agency has allocated a total of $2,240,000.00 to eligible and selected applicants.
  • The number of recipients for this funding is limited to 4 candidate(s).
  • Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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