Opportunity Information: Apply for W81XWH 10 MSRP IA
Apply for W81XWH 10 MSRP IA
- The Dept. of the Army USAMRAA in the science and technology and other research and development sector is offering a public funding opportunity titled "DoD Multiple Sclerosis Idea Award" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 12.420 Military Medical Research and Development.
- This funding opportunity was created on Jan 21, 2010 and posted on Jan 21, 2010.
- Applicants must submit their applications by Jun 10, 2010. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $2,700,000.00 to eligible and selected applicants.
- The number of recipients for this funding is limited to 4 candidate(s).
- Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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Opportunity Summary:
The DoD Multiple Sclerosis Idea Award (Funding Opportunity Number W81XWH-10-MSRP-IA) is a U.S. Department of the Army, USAMRAA-administered research funding opportunity under CFDA 12.420 (Military Medical Research and Development). It is positioned within the Science and Technology and other Research and Development category and uses either a grant or cooperative agreement as the funding instrument. The program is built to catalyze fresh, early-stage concepts in multiple sclerosis research, specifically ideas that are not yet mature but have a clear path to generating high-impact findings and opening up new lines of investigation.
At its core, this opportunity is meant to back conceptually innovative work that carries higher scientific risk than typical incremental projects, with the tradeoff being the potential for major payoff. The award explicitly emphasizes high risk, potentially high reward research that could ultimately contribute to critical discoveries about the causes of MS and how the disease progresses, and/or translate into meaningful improvements in patient care and overall quality of life. In practical terms, this means proposals are expected to push beyond established approaches, challenge current assumptions, or apply novel methods, models, or perspectives that could shift the field if successful.
Even though the program is aimed at new and developing ideas, it is not intended for unfocused exploration. Projects are expected to be anchored by a well-formulated, testable hypothesis supported by a strong scientific rationale. That combination signals what reviewers are likely looking for: bold concepts that still demonstrate careful thinking, a defensible biological or clinical premise, and a clear plan for generating interpretable results. The emphasis on hypothesis-driven work also suggests that applicants should be prepared to specify what will be tested, how it will be tested, what outcomes would support or refute the hypothesis, and why the expected results would matter for MS understanding or patient impact.
From a funding and competition standpoint, the opportunity anticipated a small number of awards, with an expected total of about four awards and an estimated total funding level of $2.7 million. There was no cost sharing or matching requirement, which reduces barriers for applicants and allows institutions to propose projects without needing to commit additional non-federal dollars as a condition of funding. Eligibility was listed as unrestricted, meaning it was open to any type of applicant entity, subject to any clarifications in the full announcement, making it broadly accessible across academia, nonprofit research organizations, hospitals, industry, and other eligible institutions.
The timeline included a posted and creation date of January 21, 2010, with an original and current closing date of June 10, 2010, and an archive date of July 10, 2010. For administrative assistance, the announcement provided support contacts for accessing the full announcement and for electronic submission help, including PA HELP at 301-619-7079 (cdmrp.pa@amedd.army.mil) and eReceipt/CDMRP Help Desk support at 301-682-5507 (help@cdmrp.org).
Frequently Asked Questions (FAQ) - DoD Multiple Sclerosis Idea Award (W81XWH-10-MSRP-IA)
What is the DoD Multiple Sclerosis Idea Award?
The DoD Multiple Sclerosis Idea Award is a U.S. Department of the Army-administered research funding opportunity (USAMRAA) designed to catalyze fresh, early-stage concepts in multiple sclerosis (MS) research. It supports conceptually innovative projects that are not yet mature but have a clear path to generating high-impact findings and opening new lines of investigation.
What is the Funding Opportunity Number (FON) for this program?
The Funding Opportunity Number is W81XWH-10-MSRP-IA.
Which federal program listing (CFDA) is associated with this opportunity?
This opportunity is associated with CFDA 12.420, titled Military Medical Research and Development.
What type of activities does this award fall under?
The opportunity is positioned within the Science and Technology and other Research and Development category.
What funding instrument is used (grant vs. cooperative agreement)?
The program uses either a grant or a cooperative agreement as the funding instrument.
What is the main purpose of the award?
The award is intended to back innovative, early-stage MS research ideas that may carry higher scientific risk than typical incremental projects, with the potential for major payoff. The goal is to enable work that could contribute to critical discoveries about the causes of MS and how the disease progresses, and/or translate into meaningful improvements in patient care and overall quality of life.
Does the program encourage high-risk research?
Yes. The award explicitly emphasizes high-risk, potentially high-reward research. Proposed work is expected to push beyond established approaches, challenge current assumptions, or apply novel methods, models, or perspectives that could shift the field if successful.
Is this funding meant for exploratory or unfocused projects?
No. While the award supports new and developing ideas, it is not intended for unfocused exploration. Projects are expected to be anchored by a well-formulated, testable hypothesis supported by a strong scientific rationale.
What kind of scientific framing does the program expect in a proposal?
Based on the opportunity description, proposals are expected to be hypothesis-driven and include a clear plan for generating interpretable results. Applicants should be prepared to specify what will be tested, how it will be tested, what outcomes would support or refute the hypothesis, and why the expected results would matter for MS understanding or patient impact.
How many awards were anticipated and what was the estimated total funding level?
The opportunity anticipated a small number of awards, with an expectation of about four awards and an estimated total funding level of $2.7 million.
Is cost sharing or matching required?
No. There was no cost sharing or matching requirement for this opportunity.
Who is eligible to apply?
Eligibility was listed as unrestricted, meaning it was open to any type of applicant entity (subject to any clarifications in the full announcement). This suggests broad access across academia, nonprofit research organizations, hospitals, industry, and other eligible institutions.
When was this opportunity posted?
The posted (and creation) date was January 21, 2010.
What was the application deadline?
The original and current closing date listed for this opportunity was June 10, 2010.
When was the opportunity archived?
The archive date was July 10, 2010.
Who administers this funding opportunity?
The opportunity is administered by the U.S. Department of the Army through USAMRAA.
Where can applicants get help accessing the full announcement?
For administrative assistance and help accessing the full announcement, the contact listed is PA HELP at 301-619-7079 or cdmrp.pa@amedd.army.mil.
Where can applicants get help with electronic submission?
For electronic submission help, the announcement lists the eReceipt/CDMRP Help Desk at 301-682-5507 or help@cdmrp.org.
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| DoD Peer Reviewed Medical Concept Award Apply for W81XWH 10 PRMRP CA Funding Number: W81XWH 10 PRMRP CA Agency: Dept. of the Army USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| DoD Peer Reviewed Medical Clinical Trial Award Apply for W81XWH 10 PRMRP CTA Funding Number: W81XWH 10 PRMRP CTA Agency: Dept. of the Army USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| DoD Peer Reviewed Medical Investigator Initiated Research Award Apply for W81XWH 10 PRMRP IIRA Funding Number: W81XWH 10 PRMRP IIRA Agency: Dept. of the Army USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| DoD Peer Reviewed Medical Technology/Therapeutic Development Award Apply for W81XWH 10 PRMRP TTDA Funding Number: W81XWH 10 PRMRP TTDA Agency: Dept. of the Army USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
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