Opportunity Information: Apply for W81XWH 15 NFRP NIA
Apply for W81XWH 15 NFRP NIA
- The Dept. of the Army USAMRAA in the science and technology and other research and development sector is offering a public funding opportunity titled "DoD Neurofibromatosis New Investigator Award" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 12.420 Military Medical Research and Development.
- This funding opportunity was created on May 6, 2015 and posted on May 6, 2015.
- Applicants must submit their applications by Jul 27, 2015. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $2,880,000.00 to eligible and selected applicants.
- The number of recipients for this funding is limited to 4 candidate(s).
- Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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Opportunity Summary:
The DoD Neurofibromatosis New Investigator Award (NFRP NIA) is a U.S. Department of Defense funding opportunity run through the Department of the Army, USAMRAA, under the Congressionally Directed Medical Research Programs (CDMRP). Its main goal is career development: it is meant to help promising early-stage independent researchers build momentum in neurofibromatosis (NF) research, and it also supports established investigators who want to pivot into NF from another field. A key point is that prior NF experience is not required, but if the principal investigator has limited NF background, the program strongly encourages bringing in a collaborator with solid NF expertise to strengthen the project and ensure the work is grounded in the field.
From a scientific scope standpoint, the program is broadly open to many types of NF-related research across the research pipeline, but it specifically excludes clinical trials. In other words, applicants can propose basic, translational, and other non clinical trial studies as long as they address NF and are positioned to advance understanding or future impact. The application must include preliminary and/or published data that connects directly to NF and supports the feasibility or rationale of the proposed project, so proposals need more than a concept; they must show some relevant evidence base already exists.
A major emphasis of the award is on rigor and reproducibility, especially for preclinical work. Applicants are expected to design and report studies using widely accepted best practices that improve translational potential, including transparent methods and careful bias control. The announcement specifically points to the Landis et al. Nature 2012 guidelines on transparent reporting, and it highlights core principles such as randomization, blinding, sample size estimation, and clear data handling rules. For projects that include animal studies, applicants are directed to consult the ARRIVE guidelines so that animal experiments are planned and ultimately reported in a way that meets modern standards for rigor, transparency, and interpretability.
Administratively, this opportunity was posted May 6, 2015, with an original and final closing date of July 27, 2015, and it was archived August 26, 2015. The funding instrument type is listed as a cooperative agreement and grant, and it falls under the Science and Technology and other Research and Development activity category. The program anticipated making about 4 awards, with an estimated total funding amount of $2,880,000, and it did not require cost sharing or matching funds. Eligibility is described as unrestricted (open to any type of entity), subject to any additional eligibility notes in the full announcement. The CFDA listing associated with it is 12.420, Military Medical Research and Development. For access or technical issues related to the full announcement, the listed support contact is the CDMRP Help Desk at 301-682-5507.
Frequently Asked Questions (FAQs)
What is the DoD Neurofibromatosis New Investigator Award (NFRP NIA)?
The DoD Neurofibromatosis New Investigator Award (NFRP NIA) is a U.S. Department of Defense funding opportunity administered through the Department of the Army (USAMRAA) under the Congressionally Directed Medical Research Programs (CDMRP). It supports research focused on neurofibromatosis (NF) while emphasizing investigator career development.
What is the main purpose of this award?
The award is primarily designed for career development. It aims to help promising early-stage independent researchers build momentum in neurofibromatosis (NF) research. It also supports established investigators who want to transition into NF research from another field.
Do applicants need prior neurofibromatosis (NF) research experience?
No. Prior NF experience is not required for the principal investigator (PI). The opportunity is structured to support investigators who are new to the NF field as well as those already working in it.
If the PI has limited NF experience, is a collaborator required?
A collaborator is not stated as strictly required, but the program strongly encourages applicants with limited NF background to include a collaborator who has strong NF expertise. The intent is to strengthen the project and ensure it is well grounded in the NF field.
What types of research are supported under this funding opportunity?
The scientific scope is broadly open to many types of NF-related research across the research pipeline. This includes basic and translational approaches and other non-clinical trial studies, as long as the work addresses NF and is positioned to advance understanding or future impact.
Are clinical trials allowed under this award?
No. Clinical trials are specifically excluded. Applicants may propose NF-related studies, but not clinical trials.
Is preliminary or published data required to apply?
Yes. The application must include preliminary and/or published data that directly connects to neurofibromatosis (NF) and supports the feasibility or rationale of the proposed project. Proposals need to present an evidence base rather than only a conceptual idea.
What does the program emphasize regarding rigor and reproducibility?
A major emphasis is placed on rigor and reproducibility, particularly for preclinical work. Applicants are expected to use widely accepted best practices that improve translational potential through transparent methods and bias control.
What specific study design practices are highlighted?
The opportunity highlights core principles commonly associated with rigorous preclinical research, including randomization, blinding, sample size estimation, and clear data handling rules.
Are there any referenced guidelines applicants are expected to follow?
Yes. The announcement points to the Landis et al. Nature 2012 guidelines on transparent reporting. For projects involving animal studies, applicants are directed to consult the ARRIVE guidelines to ensure animal experiments are planned and reported with appropriate rigor and transparency.
Which agency and program administer this opportunity?
The opportunity is run through the Department of the Army, USAMRAA, and is part of the Congressionally Directed Medical Research Programs (CDMRP) within the U.S. Department of Defense.
What is the funding instrument type?
The funding instrument type is listed as a cooperative agreement and grant.
What activity category does this opportunity fall under?
It is categorized under Science and Technology and other Research and Development.
How many awards were anticipated and what was the estimated total funding?
The program anticipated making about 4 awards, with an estimated total funding amount of $2,880,000.
Is cost sharing or matching required?
No. The opportunity states that it did not require cost sharing or matching funds.
Who was eligible to apply?
Eligibility is described as unrestricted (open to any type of entity), subject to any additional eligibility notes in the full announcement.
What is the CFDA number associated with this opportunity?
The CFDA listing associated with this opportunity is 12.420, Military Medical Research and Development.
When was this grant opportunity posted and when did it close?
The opportunity was posted on May 6, 2015. The original and final closing date was July 27, 2015.
When was the opportunity archived?
It was archived on August 26, 2015.
Who should applicants contact for help accessing the full announcement or for technical issues?
For access or technical issues related to the full announcement, the listed support contact is the CDMRP Help Desk at 301-682-5507.
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