Opportunity Information: Apply for W81XWH 14 OCRP IIRA

  • The Dept. of the Army USAMRAA in the science and technology and other research and development sector is offering a public funding opportunity titled "DoD Ovarian Cancer Investigator Initiated Research Award" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 12.420 Military Medical Research and Development.
  • This funding opportunity was created on Apr 15, 2014 and posted on Apr 15, 2014.
  • Applicants must submit their applications by Aug 27, 2014. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $2,880,000.00 to eligible and selected applicants.
  • The number of recipients for this funding is limited to 4 candidate(s).
  • Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
Apply for W81XWH 14 OCRP IIRA

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Opportunity Summary:

The DoD Ovarian Cancer Research Program (OCRP) Investigator Initiated Research Award (IIRA) is a U.S. Department of the Army, USAMRAA-administered funding opportunity designed to back ovarian cancer studies that can make a meaningful, measurable difference in the field, either by advancing scientific understanding or by improving patient care. The program is intentionally broad in scientific scope: proposed projects can sit anywhere along the research pipeline, from basic laboratory work that uncovers mechanisms of disease, through translational efforts that move findings toward clinical application. A key feature of the award is that it is genuinely investigator-initiated, meaning the central idea is expected to come from the applicant rather than from a narrow topic list, and that idea can be grounded in many kinds of real-world insight, including laboratory discoveries, population-based observations, clinical experience with patients, or even well-supported anecdotal signals that motivate a testable hypothesis.

A non-negotiable requirement is that applications include preliminary data that are directly relevant to ovarian cancer and that credibly support the proposed approach. In practical terms, this signals that the program is not intended for purely speculative concepts; instead, it favors projects that already have some proof-of-concept, feasibility evidence, or early results that justify the next step. The overall intent is to fund studies that are positioned to generate impactful outcomes, whether those outcomes are new biological insights, validated targets, improved diagnostics, better risk stratification, or steps toward therapies and care practices that could benefit patients.

Administratively, this opportunity was released under Funding Opportunity Number W81XWH-14-OCRP-IIRA and offered funding through either grants or cooperative agreements, categorized under Science and Technology and other Research and Development. The total estimated funding for the cycle was $2,880,000, with an expectation of making about four awards, and it did not require cost sharing or matching funds. Eligibility was listed as unrestricted, meaning it was broadly open to applicant organizations or entities, subject to any additional eligibility details provided in the full announcement text. The opportunity was posted on April 15, 2014, with an application closing date of August 27, 2014, and it was archived on September 26, 2014. The program is associated with CFDA number 12.420 (Military Medical Research and Development). For applicants needing help accessing the full announcement or using the submission system, the point of contact provided was the CDMRP Help Desk (help@eBRAP.org, 301-682-5507).

FAQs: DoD Ovarian Cancer Research Program (OCRP) Investigator Initiated Research Award (IIRA)

What is the OCRP Investigator Initiated Research Award (IIRA)?

The OCRP Investigator Initiated Research Award (IIRA) is a U.S. Department of Defense ovarian cancer funding opportunity administered by the U.S. Department of the Army through USAMRAA. It is designed to support ovarian cancer research projects that can make a meaningful, measurable difference in the field by advancing scientific knowledge and/or improving patient care.

What is the main purpose of this award?

The intent is to fund studies that are positioned to generate impactful outcomes in ovarian cancer, such as new biological insights, validated targets, improved diagnostics, better risk stratification, or steps toward therapies and care practices that could benefit patients.

What does "investigator-initiated" mean for this award?

"Investigator-initiated" means the central research idea is expected to come from the applicant rather than being constrained by a narrow set of pre-defined topics. The applicant proposes the scientific concept and approach based on their own rationale and supporting evidence.

How broad is the scientific scope of eligible projects?

The opportunity is intentionally broad. Proposed projects may fall anywhere along the research pipeline, including basic laboratory studies that explore mechanisms of disease as well as translational projects intended to move findings toward clinical application.

What kinds of insights can justify the proposed research idea?

The proposed idea can be grounded in many kinds of real-world insight, including laboratory discoveries, population-based observations, clinical experience with patients, or well-supported anecdotal signals that motivate a testable hypothesis.

Is preliminary data required?

Yes. A non-negotiable requirement is that applications include preliminary data that are directly relevant to ovarian cancer and that credibly support the proposed approach.

What does the preliminary data need to show?

Based on the description provided, the preliminary data should support the feasibility or proof-of-concept for the proposed work and justify the next step. The program is not intended for purely speculative concepts.

Does the award support purely speculative or early-concept ideas without supporting evidence?

No. The program signals that it favors projects with ovarian cancer-relevant preliminary data rather than ideas that are purely speculative without direct supporting evidence.

What types of outcomes does the program aim to produce?

Examples of intended impactful outcomes include: new biological insights, validated targets, improved diagnostics, better risk stratification, and progress toward therapies or improved patient care practices in ovarian cancer.

What is the Funding Opportunity Number (FON) for this award?

The Funding Opportunity Number listed is W81XWH-14-OCRP-IIRA.

Who administers this funding opportunity?

The opportunity is administered by the U.S. Department of the Army through USAMRAA.

What funding mechanisms were used for this opportunity?

Funding was offered through either grants or cooperative agreements.

What categories does this opportunity fall under?

The opportunity was categorized under Science and Technology and other Research and Development.

How much total funding was estimated for this cycle?

The total estimated funding for the cycle was $2,880,000.

How many awards were expected?

The opportunity expected to make about four awards.

Was cost sharing or matching required?

No. The opportunity did not require cost sharing or matching funds.

Who was eligible to apply?

Eligibility was listed as unrestricted, meaning it was broadly open to applicant organizations or entities, subject to any additional eligibility details provided in the full announcement text.

When was the opportunity posted?

The opportunity was posted on April 15, 2014.

What was the application deadline?

The application closing date was August 27, 2014.

Is this opportunity still open?

No. It was archived on September 26, 2014.

What CFDA number is associated with this program?

The program is associated with CFDA number 12.420 (Military Medical Research and Development).

Where can applicants get help with the full announcement or the submission system?

Applicants needing help accessing the full announcement or using the submission system were directed to the CDMRP Help Desk at help@eBRAP.org or 301-682-5507.

What kind of research pipeline stages are explicitly mentioned as eligible?

The description explicitly mentions projects ranging from basic laboratory work that uncovers disease mechanisms through translational efforts that move findings toward clinical application.

Does the description indicate the program focuses only on patient care, or also on scientific understanding?

It explicitly supports both: projects can advance scientific understanding and/or improve patient care, as long as they are positioned to make a meaningful, measurable difference.

If eligibility is "unrestricted," are there still potential limitations?

The provided summary notes that unrestricted eligibility is subject to any additional eligibility details in the full announcement text. In other words, "unrestricted" suggests broad openness, but the definitive eligibility rules would be in the full announcement.

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