Opportunity Information: Apply for W81XWH 15 OCRP IIRA

  • The Dept. of the Army USAMRAA in the science and technology and other research and development sector is offering a public funding opportunity titled "DoD Ovarian Cancer Investigator Initiated Research Award" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 12.420 Military Medical Research and Development.
  • This funding opportunity was created on Mar 23, 2015 and posted on Mar 23, 2015.
  • Applicants must submit their applications by Aug 12, 2015. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $4,320,000.00 to eligible and selected applicants.
  • The number of recipients for this funding is limited to 6 candidate(s).
  • Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
Apply for W81XWH 15 OCRP IIRA

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Opportunity Summary:

The DoD Ovarian Cancer Research Program (OCRP) Investigator Initiated Research Award (IIRA) is a Department of the Army, U.S. Army Medical Research Acquisition Activity (USAMRAA) funding opportunity designed to support strong, investigator-driven research projects in ovarian cancer. The program is aimed at backing meritorious basic and clinically oriented studies that can advance understanding of ovarian cancer and move the field forward, while still emphasizing scientific rigor and a well-justified approach. Although the research can be clinically oriented, this particular award mechanism does not support ovarian cancer clinical trials, so applicants need to propose work that stops short of interventional trial activity and instead focuses on foundational, mechanistic, translational, or other non-trial clinical research efforts.

Projects may cover any point along the research spectrum, from basic laboratory investigations through translational research that bridges discoveries toward potential applications. The opportunity explicitly allows the core idea to come from multiple sources, including laboratory findings, population-based studies, clinicians firsthand observations from patient care, or even anecdotal evidence, as long as the proposal turns that initial insight into a logically argued and scientifically sound research plan. Competitiveness depends on demonstrating clear reasoning and a strong scientific rationale grounded in a critical review and analysis of the existing literature, meaning applicants are expected to show they understand the state of the science, the gaps their work will address, and why their approach is likely to produce meaningful, interpretable results.

A key requirement is the inclusion of preliminary data. Applications must provide preliminary findings that are relevant to ovarian cancer and that directly support the proposed project, signaling that the concept is feasible and that the team is positioned to execute the work. In practice, this means proposals should not be purely speculative; they should be anchored by early evidence that aligns with the specific hypotheses, methods, and objectives being proposed.

Administratively, this opportunity was posted March 23, 2015 under Funding Opportunity Number W81XWH-15-OCRP-IIRA and falls under CFDA 12.420 (Military Medical Research and Development). The funding instrument listed includes cooperative agreement and grant mechanisms, with an expected six awards and an estimated total funding level of $4,320,000. There is no cost sharing or matching requirement. Eligibility is described as unrestricted, meaning it is open to any type of entity, subject to any additional eligibility clarifications in the full announcement. The original and current closing date was August 12, 2015, with an archive date of September 11, 2015.

For applicant support, the announcement directs individuals who have trouble accessing the full posting to contact the CDMRP Help Desk at 301-682-5507 or help@eBRAP.org.

Frequently Asked Questions (FAQs)

What is the DoD Ovarian Cancer Research Program (OCRP) Investigator Initiated Research Award (IIRA)?

The OCRP Investigator Initiated Research Award (IIRA) is a Department of Defense funding opportunity managed by the Department of the Army, U.S. Army Medical Research Acquisition Activity (USAMRAA). It is designed to support strong, investigator-driven research projects focused on ovarian cancer.

What types of ovarian cancer research does this award support?

This award supports meritorious basic research and clinically oriented studies that advance understanding of ovarian cancer and move the field forward. Projects may span the research spectrum, including basic laboratory investigations and translational research.

Are ovarian cancer clinical trials allowed under this award mechanism?

No. Although the research may be clinically oriented, this award mechanism does not support ovarian cancer clinical trials. Proposed work should stop short of interventional trial activity and instead focus on foundational, mechanistic, translational, or other non-trial clinical research efforts.

How investigator-driven is this opportunity?

The opportunity is explicitly intended to support investigator-initiated (investigator-driven) projects, meaning the research questions and approach are proposed by the applicant rather than being narrowly prescribed by the sponsor.

What points along the research spectrum are considered appropriate?

Projects may address any point along the research spectrum, from basic laboratory studies through translational research that bridges discoveries toward potential applications.

What kinds of observations or evidence can serve as the starting point for a project idea?

The core idea may come from multiple sources, including laboratory findings, population-based studies, clinicians firsthand observations from patient care, or anecdotal evidence, as long as the proposal develops that insight into a logically argued and scientifically sound research plan.

What makes an application competitive based on the description provided?

Competitiveness depends on demonstrating clear reasoning and a strong scientific rationale grounded in a critical review and analysis of the existing literature. Applicants are expected to show they understand the current state of the science, the gaps their work will address, and why their approach is likely to produce meaningful, interpretable results.

Is preliminary data required?

Yes. A key requirement is the inclusion of preliminary data.

What kind of preliminary data is expected?

Applications must provide preliminary findings that are relevant to ovarian cancer and directly support the proposed project. The preliminary data should indicate feasibility and show that the team is positioned to execute the work.

Can an application be purely exploratory or speculative?

The description indicates proposals should not be purely speculative. They should be anchored by early evidence that aligns with the specific hypotheses, methods, and objectives being proposed.

What is the Funding Opportunity Number for this announcement?

The Funding Opportunity Number is W81XWH-15-OCRP-IIRA.

When was this opportunity posted?

The opportunity was posted on March 23, 2015.

What CFDA number is associated with this funding opportunity?

The opportunity falls under CFDA 12.420 (Military Medical Research and Development).

What funding instruments are listed for this opportunity?

The funding instruments listed include cooperative agreement and grant mechanisms.

How many awards were expected?

The announcement listed an expectation of six awards.

What was the estimated total funding level?

The estimated total funding level was $4,320,000.

Is cost sharing or matching required?

No. The announcement states there is no cost sharing or matching requirement.

Who is eligible to apply?

Eligibility is described as unrestricted, meaning it is open to any type of entity, subject to any additional eligibility clarifications in the full announcement.

What was the application closing date?

The original and current closing date was August 12, 2015.

When was the archive date for this opportunity?

The archive date was September 11, 2015.

Who do applicants contact if they have trouble accessing the full posting?

Applicants who have trouble accessing the full posting are directed to contact the CDMRP Help Desk at 301-682-5507 or help@eBRAP.org.

Which organization is associated with administering or managing this opportunity?

The opportunity is associated with the Department of the Army, U.S. Army Medical Research Acquisition Activity (USAMRAA).

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Previous opportunity: 2016 EHP External Research Support

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