Opportunity Information: Apply for W81XWH 10 PRCRP CA

  • The Dept. of the Army USAMRAA in the science and technology and other research and development sector is offering a public funding opportunity titled "DOD Peer Reviewed Cancer Concept Award" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 12.420 Military Medical Research and Development.
  • This funding opportunity was created on Aug 16, 2010 and posted on Jul 14, 2010.
  • Applicants must submit their applications by Sep 29, 2010. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $450,000.00 to eligible and selected applicants.
  • The number of recipients for this funding is limited to 4 candidate(s).
  • Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
Apply for W81XWH 10 PRCRP CA

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Opportunity Summary:

The DOD Peer Reviewed Cancer Research Program (PRCRP) Concept Award (Funding Opportunity Number W81XWH-10-PRCRP-CA) is a U.S. Army/USAMRAA funding opportunity designed to back early-stage, high-risk cancer research ideas that could open up completely new directions in the field. The core purpose is to support the exploration of a highly innovative concept or an untested theory rather than incremental work that simply extends an existing, already-established research project. This award is meant to fund bold, exploratory studies where the payoff could be substantial, even if the chance of failure is higher than in more conventional research programs.

A key feature of this Concept Award is that preliminary data cannot be included or used as a selling point in the application. Instead, applicants must provide a clear scientific rationale that explains why the idea is plausible and worth pursuing, even without prior supporting results. In practical terms, the program is intended to help a Principal Investigator generate the initial proof-of-concept or foundational findings that could later support applications to other grant mechanisms that do require preliminary data. The emphasis is on novelty, creativity, and the potential to uncover new investigative avenues, not on delivering a predictable next step in an ongoing line of work.

Proposed projects must fall strictly within at least one of the FY10 PRCRP Topic Areas, and no other topic areas are permitted. For FY10, Congress directed PRCRP funds to the following areas: melanoma and other skin cancers; pediatric brain tumors; genetic cancer research and genomic medicine; kidney cancer; blood cancers; colorectal cancer; Listeria vaccine for cancer; and radiation protection utilizing nanotechnology. Just as important as what is allowed is what is explicitly not allowed: applications must not propose research focused on breast, prostate, lung, or ovarian cancers.

From an administrative and funding perspective, the opportunity was offered under either a grant or cooperative agreement structure and is categorized under Science and Technology and other Research and Development. The program anticipated making about 4 awards, with an estimated total funding amount of $450,000, and it did not require cost sharing or matching. Eligibility was listed as unrestricted, meaning the program was broadly open to various applicant entity types, subject to any additional eligibility clarifications contained in the full announcement.

Key dates tied to the solicitation show it was posted on July 14, 2010, with an application closing date of September 29, 2010, and an archive date of October 29, 2010. The CFDA number associated with the opportunity is 12.420 (Military Medical Research and Development), reflecting its placement within the Department of Defense medical research portfolio. For applicant support, the announcement provided contact points for assistance accessing the full posting and for electronic submission troubleshooting, including PA HELP (301-619-7079, cdmrp.pa@amedd.army.mil) and the eReceipt/CDMRP Help Desk (301-682-5507, help@cdmrp.org).

FAQs: DOD Peer Reviewed Cancer Research Program (PRCRP) Concept Award (W81XWH-10-PRCRP-CA)

What is the PRCRP Concept Award (W81XWH-10-PRCRP-CA)?

The PRCRP Concept Award is a Department of Defense (U.S. Army/USAMRAA) funding opportunity intended to support early-stage, high-risk cancer research concepts. It focuses on bold, exploratory ideas that could open completely new directions in cancer research, rather than incremental extensions of established projects.

What is the main purpose of this Concept Award?

The purpose is to support the exploration of a highly innovative concept or untested theory. The program is designed to help investigators generate initial proof-of-concept or foundational findings that may enable future applications to other grant mechanisms that require preliminary data.

What kind of research is this award intended to support?

It is intended to fund novel, creative, and potentially transformative studies where the payoff could be substantial, even if the probability of failure is higher than in more conventional research programs. The emphasis is on opening new investigative avenues, not producing a predictable next step in an ongoing research line.

Does this award support incremental or extension studies?

No. The opportunity explicitly emphasizes highly innovative concepts and untested theories rather than incremental work that extends an already-established research project.

Can applicants include preliminary data in the application?

No. Preliminary data cannot be included or used as a selling point. Applications must instead present a clear scientific rationale explaining why the idea is plausible and worth pursuing without prior supporting results.

If preliminary data is not allowed, what should the application emphasize?

The application should emphasize the scientific rationale for the concept, including why the idea is plausible, innovative, and worth exploring. The program places weight on novelty, creativity, and the potential to open new directions.

What topic areas are eligible under this FY10 PRCRP Concept Award?

Proposed projects must fall strictly within at least one FY10 PRCRP Topic Area. The FY10 topic areas listed in the opportunity are:

  • Melanoma and other skin cancers
  • Pediatric brain tumors
  • Genetic cancer research and genomic medicine
  • Kidney cancer
  • Blood cancers
  • Colorectal cancer
  • Listeria vaccine for cancer
  • Radiation protection utilizing nanotechnology

Are projects allowed to propose topic areas outside the FY10 PRCRP list?

No. Projects must fall strictly within at least one of the FY10 PRCRP Topic Areas, and no other topic areas are permitted.

Which cancer areas are explicitly not allowed for this opportunity?

Applications must not propose research focused on breast cancer, prostate cancer, lung cancer, or ovarian cancer.

What agency or organization is offering this funding opportunity?

The opportunity is a U.S. Army/USAMRAA (U.S. Army Medical Research Acquisition Activity) funding opportunity under the Department of Defense.

What is the Funding Opportunity Number for this Concept Award?

The Funding Opportunity Number is W81XWH-10-PRCRP-CA.

How is this opportunity categorized?

It is categorized under Science and Technology and other Research and Development.

What funding instrument types were anticipated?

The opportunity was offered under either a grant or a cooperative agreement structure.

How many awards were anticipated and what was the estimated total funding?

The program anticipated making about 4 awards, with an estimated total funding amount of $450,000.

Is cost sharing or matching required?

No. The opportunity did not require cost sharing or matching.

Who was eligible to apply?

Eligibility was listed as unrestricted, meaning it was broadly open to various applicant entity types, subject to any additional eligibility clarifications contained in the full announcement.

What are the key dates for this funding opportunity?

The opportunity was posted on July 14, 2010. The application closing date was September 29, 2010. The archive date was October 29, 2010.

What CFDA number is associated with this program?

The CFDA number associated with the opportunity is 12.420 (Military Medical Research and Development).

Where can applicants get help accessing the full posting?

For assistance accessing the full posting, the announcement listed PA HELP at 301-619-7079 or cdmrp.pa@amedd.army.mil.

Where can applicants get help with electronic submission or eReceipt issues?

For electronic submission troubleshooting, the announcement listed the eReceipt/CDMRP Help Desk at 301-682-5507 or help@cdmrp.org.

What is the practical goal of funding a concept without preliminary data?

The practical goal is to help a Principal Investigator generate initial proof-of-concept or foundational findings that could later support applications to other grant mechanisms that do require preliminary data.

What is the overall emphasis used to evaluate fit for this Concept Award (based on the description)?

Based on the description, fit centers on novelty, creativity, and the potential to uncover new investigative avenues within the allowed FY10 PRCRP topic areas, while avoiding incremental extensions and excluding disallowed cancer focuses.

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