Opportunity Information: Apply for W81XWH 15 PRCRP HA

  • The Dept. of the Army USAMRAA in the science and technology and other research and development sector is offering a public funding opportunity titled "DoD Peer Reviewed Cancer Horizon Award" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 12.420 Military Medical Research and Development.
  • This funding opportunity was created on Jul 1, 2015 and posted on Jul 1, 2015.
  • Applicants must submit their applications by Sep 29, 2015. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $1,560,000.00 to eligible and selected applicants.
  • The number of recipients for this funding is limited to 13 candidate(s).
  • Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
Apply for W81XWH 15 PRCRP HA

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Opportunity Summary:

The DoD Peer Reviewed Cancer Horizon Award (FY15) is a Department of the Army program run through the Congressionally Directed Medical Research Programs (CDMRP) that is designed specifically to help junior scientists launch independent, impactful cancer research careers while working under the guidance of an experienced cancer researcher serving as a mentor. The core idea is to give early-career researchers room to propose and drive a scientifically sound project in the cancer field, while also building their skills, reputation, and trajectory as future leaders in cancer research. Even though the work is mentored, the junior investigator is treated as the Principal Investigator (PI), and the application is expected to center on the PI's ideas, growth, and potential rather than the mentor's established program.

A key feature of this mechanism is that the proposed study should be intellectually developed by the PI, with support from the mentor, and presented with clear logic and a strong scientific rationale. Unlike many other research awards, preliminary data are not required, which lowers the barrier for promising but newer investigators who may not yet have a deep portfolio of results. At the same time, the program is not intended for clinical trials; proposals involving clinical trials are explicitly not supported under this award, keeping the focus on preclinical, translational, mechanistic, or other non-trial research approaches that can still meaningfully advance cancer science.

Eligibility is focused on two groups of junior investigators: qualified predoctoral candidates and postdoctoral fellows, both of whom must be working in the mentor's laboratory at the time the application is submitted. Predoctoral candidates must have completed their coursework and passed qualifying examinations by the application deadline. They are also expected to be relatively early in their PhD timeline, described as being within two years of acceptance as a doctoral candidate, having completed all laboratory rotations, and already positioned in the mentor's lab. Postdoctoral fellows must be within three years of their terminal degree at the time of submission, with allowable exclusions for time spent in residency or on family medical leave. In addition to meeting these timing and lab-placement requirements, applicants are evaluated on their record of accomplishments (for example, publications, awards, and research recognition) as an indicator of their potential to contribute to the program's targeted cancer research areas.

Projects must align with at least one of the FY15 Peer Reviewed Cancer Research Program (PRCRP) Topic Areas established by Congress. Importantly, the award does not accept research applications focused on breast, prostate, lung cancer (with the exception that mesothelioma is allowed), or ovarian cancer. The accepted FY15 Topic Areas include colorectal cancer; genetic cancer research; kidney cancer; Listeria vaccine for cancer; liver cancer (new for FY15); melanoma and other skin cancers; mesothelioma; myeloproliferative disorders; neuroblastoma; pancreatic cancer; and stomach cancer (new for FY15). This topic restriction is a major strategic consideration for applicants, since proposals outside these areas are not competitive regardless of scientific merit.

From an administrative and funding standpoint, the opportunity was offered under Funding Opportunity Number W81XWH-15-PRCRP-HA as a discretionary program using a cooperative agreement grant instrument under the Science and Technology and other Research and Development funding activity category. The CFDA listing is 12.420 (Military Medical Research and Development). For FY15, the program anticipated making about 13 awards with an estimated total funding pool of $1,560,000, and it did not require cost sharing or matching. The opportunity was posted on July 1, 2015, with an application deadline of September 29, 2015, and an archive date of October 29, 2015. Eligibility was listed as unrestricted in general terms (open to any entity type), although the specific PI eligibility requirements described above effectively shape who can lead an application.

For help accessing the full announcement or navigating submission issues, the listing directs applicants to the CDMRP Help Desk at 301-682-5507.

DoD Peer Reviewed Cancer Horizon Award (FY15) - FAQs

What is the DoD Peer Reviewed Cancer Horizon Award (FY15)?

The DoD Peer Reviewed Cancer Horizon Award (FY15) is a Department of the Army funding opportunity administered through the Congressionally Directed Medical Research Programs (CDMRP). It is intended to help junior scientists launch independent, high-impact cancer research careers while working under the guidance of an experienced cancer researcher who serves as a mentor.

What is the main purpose of this award mechanism?

The mechanism is built to give early-career investigators space to propose and drive a scientifically sound cancer research project while also developing as future leaders in cancer research. The application is expected to focus on the junior investigator's ideas, growth, and potential.

Is this a mentored award or an independent PI award?

It is a mentored mechanism, but the junior investigator is treated as the Principal Investigator (PI). The proposal should be centered on the PI's intellectual contribution and career development rather than being an extension of the mentor's established research program.

Who is expected to intellectually develop the proposed research project?

The proposed study should be intellectually developed by the PI, with support from the mentor. The application should present clear logic and a strong scientific rationale for the project.

Are preliminary data required to apply?

No. Preliminary data are not required for this award, which reduces barriers for promising investigators who may not yet have an extensive results portfolio.

Are clinical trials allowed under this award?

No. Proposals involving clinical trials are explicitly not supported under this award. The focus is on non-trial research approaches such as preclinical, translational, mechanistic, or other research that can advance cancer science without being a clinical trial.

Who is eligible to apply as the PI?

Eligibility is focused on two groups of junior investigators: qualified predoctoral candidates and postdoctoral fellows. Both must be working in the mentor's laboratory at the time the application is submitted.

What are the eligibility requirements for predoctoral candidates?

Predoctoral candidates must have completed their coursework and passed qualifying examinations by the application deadline. They are expected to be early in their PhD timeline, described as within two years of acceptance as a doctoral candidate, having completed all laboratory rotations, and already positioned in the mentor's lab.

What are the eligibility requirements for postdoctoral fellows?

Postdoctoral fellows must be within three years of their terminal degree at the time of submission. Allowable exclusions are noted for time spent in residency or on family medical leave.

Do applicants have to be in the mentor's lab when they submit the application?

Yes. Both eligible predoctoral candidates and postdoctoral fellows must be working in the mentor's laboratory at the time the application is submitted.

How are applicants evaluated beyond basic eligibility?

Applicants are evaluated on their record of accomplishments (such as publications, awards, and research recognition) as an indicator of potential to contribute to the program's targeted cancer research areas.

Does my research topic have to match specific PRCRP Topic Areas?

Yes. Projects must align with at least one of the FY15 Peer Reviewed Cancer Research Program (PRCRP) Topic Areas established by Congress. Topic alignment is a core requirement and is described as a major strategic consideration.

What cancer research areas are included as accepted FY15 PRCRP Topic Areas?

The accepted FY15 Topic Areas include: colorectal cancer; genetic cancer research; kidney cancer; Listeria vaccine for cancer; liver cancer (new for FY15); melanoma and other skin cancers; mesothelioma; myeloproliferative disorders; neuroblastoma; pancreatic cancer; and stomach cancer (new for FY15).

Are there cancer types that are not accepted under this award?

Yes. The award does not accept research applications focused on breast cancer, prostate cancer, lung cancer (with the exception that mesothelioma is allowed), or ovarian cancer.

If my idea is scientifically strong but outside the allowed Topic Areas, can it still be competitive?

No. Proposals outside the listed FY15 Topic Areas are described as not competitive regardless of scientific merit.

Is mesothelioma allowed even though lung cancer is excluded?

Yes. While lung cancer is excluded, mesothelioma is explicitly allowed and is listed among the accepted FY15 Topic Areas.

What is the Funding Opportunity Number for this announcement?

The Funding Opportunity Number is W81XWH-15-PRCRP-HA.

Which organization administers this opportunity?

The opportunity is a Department of the Army program administered through CDMRP (Congressionally Directed Medical Research Programs).

What type of funding instrument is used?

The listing describes the award as a cooperative agreement grant instrument.

What is the CFDA number for this program?

The CFDA listing is 12.420 (Military Medical Research and Development).

What funding activity category is associated with this opportunity?

The listing places the opportunity under the Science and Technology and other Research and Development funding activity category.

How many awards were anticipated and what was the estimated total funding?

For FY15, the program anticipated making about 13 awards with an estimated total funding pool of $1,560,000.

Is cost sharing or matching required?

No. The opportunity did not require cost sharing or matching.

When was this opportunity posted and when was the application due?

The opportunity was posted on July 1, 2015, and the application deadline was September 29, 2015.

What does the archive date mean for this listing?

The listing includes an archive date of October 29, 2015, indicating the opportunity was archived after that date.

Is eligibility restricted to specific entity types?

The listing states eligibility was unrestricted in general terms (open to any entity type), but the PI eligibility rules (predoctoral or postdoctoral status, timing, and being in the mentor's lab at submission) effectively determine who can lead an application.

Where can applicants get help with the full announcement or submission issues?

Applicants are directed to the CDMRP Help Desk at 301-682-5507 for assistance accessing the full announcement or navigating submission issues.

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