Opportunity Information: Apply for W81XWH 13 PRCRP IA

  • The Dept. of the Army USAMRAA in the science and technology and other research and development sector is offering a public funding opportunity titled "DoD Peer Reviewed Cancer Idea Award with Special Focus" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 12.420 Military Medical Research and Development.
  • This funding opportunity was created on May 21, 2013 and posted on May 21, 2013.
  • Applicants must submit their applications by Oct 22, 2013. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $4,800,000.00 to eligible and selected applicants.
  • The number of recipients for this funding is limited to 10 candidate(s).
  • Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
Apply for W81XWH 13 PRCRP IA

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Opportunity Summary:

The DoD Peer Reviewed Cancer Research Program (PRCRP) Idea Award with Special Focus is a Department of the Army (USAMRAA) funding opportunity designed to push forward genuinely new and exploratory cancer research ideas that matter to the military community. The program is aimed at concepts that are directly relevant to service members, their families, and other military beneficiaries, which means applicants need to make a clear case that the cancer problem being addressed has a meaningful connection to those populations. The core purpose of this mechanism is to give researchers room to test bold ideas that could reshape how people think about cancer initiation or progression, even if those ideas are unproven at the start.

This award specifically targets innovative, untested, high-risk and potentially high-reward research. Proposals are expected to be novel in a real sense, not simply a continuation of what a lab is already doing. The opportunity emphasizes that the project should not be a logical next step in an established line of work, and it is not meant to fund incremental advances based on already published findings. Instead, the strongest applications will introduce a new paradigm, challenge an existing paradigm, or approach a known cancer problem from an unconventional angle using uniquely creative methods or frameworks. The goal is to support research that would be difficult to fund through more conservative mechanisms because it is exploratory and may not yet have a large evidence base.

Even though the work is intended to be exploratory, the proposal still needs to be rigorous. Applicants are expected to present a well-formulated, testable hypothesis supported by a strong scientific rationale and a solid study design. In other words, the program is not asking for speculation without structure; it is asking for carefully planned experiments that can decisively generate insight or data, even if the underlying idea is new and unproven. A key expectation is that the project will produce robust preliminary data by the end of the award period, creating a foundation for future, larger studies that clarify mechanisms behind how cancers start or how they progress.

A notable feature of this mechanism is its stance on preliminary data. Inclusion of preliminary data is actively discouraged, which signals that applicants should not feel pressured to demonstrate extensive prior results in order to compete. The announcement also clarifies that this award is not intended to support ongoing research already underway in the applicant’s laboratory. If preliminary results are included, they should be limited and consistent with the exploratory nature of the mechanism, such as serendipitous findings or very small sample observations rather than a body of data that suggests the work is already established.

Administratively, this opportunity was released under Funding Opportunity Number W81XWH-13-PRCRP-IA, titled "DoD Peer Reviewed Cancer Idea Award with Special Focus." The funding instrument type listed is a cooperative agreement or grant, under the Science and Technology and other Research and Development activity category. The program anticipated making about 10 awards, with an estimated total funding amount of $4,800,000, and it did not require cost sharing or matching funds. Eligibility was listed as unrestricted (open to any type of entity), subject to any additional eligibility clarifications in the full announcement. The opportunity was posted May 21, 2013, with an original and final closing date of October 22, 2013, and it was archived November 21, 2013. For access issues or help with the full announcement, the contact listed is the CDMRP Help Desk at 301-682-5507.

FAQs: DoD Peer Reviewed Cancer Research Program (PRCRP) Idea Award with Special Focus

What is this funding opportunity?

This is the Department of Defense (DoD) Peer Reviewed Cancer Research Program (PRCRP) Idea Award with Special Focus, a Department of the Army (USAMRAA) funding opportunity intended to accelerate genuinely new, exploratory cancer research ideas that are relevant to the military community.

What is the official Funding Opportunity Number (FON)?

The Funding Opportunity Number is W81XWH-13-PRCRP-IA.

What is the official title of the opportunity?

The title is "DoD Peer Reviewed Cancer Idea Award with Special Focus."

What is the main goal of the Idea Award with Special Focus?

The main goal is to give researchers room to test bold, high-risk, potentially high-reward ideas that could reshape how people think about cancer initiation or progression, even if those ideas are unproven at the start.

What kind of research is this award trying to support?

The award targets innovative, untested, high-risk research with the potential for high reward. The strongest proposals are expected to be truly novel (not incremental) and may introduce a new paradigm, challenge an existing paradigm, or tackle a cancer problem using unconventional angles, methods, or frameworks.

Is this intended to fund incremental or "next-step" research?

No. The opportunity emphasizes that the project should not be a logical next step in an established line of work and is not meant to fund incremental advances based on already published findings.

Can this award be used to support ongoing research already underway in a lab?

No. The announcement clarifies that the award is not intended to support ongoing research already underway in the applicant's laboratory.

How important is military relevance?

Military relevance is central. Applicants are expected to make a clear case that the cancer problem being addressed has a meaningful connection to service members, their families, and other military beneficiaries.

Who is the research supposed to matter to, specifically?

The program is aimed at concepts directly relevant to service members, their families, and other military beneficiaries.

Does the program require a hypothesis and rigorous study design?

Yes. Even though the work is exploratory, proposals are expected to include a well-formulated, testable hypothesis supported by a strong scientific rationale and a solid study design.

Is speculation enough for this mechanism?

No. The program is not asking for speculation without structure. It is asking for carefully planned experiments designed to generate decisive insight or data, even if the idea itself is new and unproven.

Are applicants expected to generate preliminary data during the award?

Yes. A key expectation is that the project will produce robust preliminary data by the end of the award period, creating a foundation for future, larger studies.

Are applicants required to include preliminary data with the application?

No. Inclusion of preliminary data is actively discouraged, signaling that applicants should not feel pressured to have extensive prior results to be competitive.

If preliminary data is discouraged, can any preliminary results be included at all?

If preliminary results are included, they should be limited and consistent with the exploratory nature of the mechanism, such as serendipitous findings or very small sample observations (not a substantial body of data suggesting the work is already established).

Why does the program discourage extensive preliminary data?

Based on the description provided, discouraging preliminary data reinforces the program's purpose: supporting untested, high-risk ideas that may not yet have a large evidence base and would be difficult to fund through more conservative mechanisms.

What broader research outcome is this award trying to enable?

The mechanism is intended to generate robust preliminary data and insights that can serve as a foundation for future, larger studies that clarify mechanisms behind how cancers start or how they progress.

What type of funding instrument is used?

The funding instrument type listed is a cooperative agreement or grant.

What activity category does this opportunity fall under?

It is listed under the Science and Technology and other Research and Development activity category.

How many awards were anticipated?

The program anticipated making about 10 awards.

What was the estimated total funding amount?

The estimated total funding amount was $4,800,000.

Is cost sharing or matching required?

No. Cost sharing or matching funds were not required.

Who is eligible to apply?

Eligibility was listed as unrestricted (open to any type of entity), subject to any additional eligibility clarifications in the full announcement.

When was the opportunity posted?

The opportunity was posted on May 21, 2013.

What were the closing dates?

The original closing date and the final closing date were both October 22, 2013.

Is this opportunity still open?

No. It was archived on November 21, 2013, and the final closing date was October 22, 2013.

Who can applicants contact for help accessing the full announcement?

For access issues or help with the full announcement, the listed contact is the CDMRP Help Desk at 301-682-5507.

Which organization released this opportunity?

The opportunity is described as a Department of the Army (USAMRAA) funding opportunity under the DoD PRCRP.

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