Opportunity Information: Apply for W81XWH 10 PRMRP CTA
Apply for W81XWH 10 PRMRP CTA
- The Dept. of the Army USAMRAA in the science and technology and other research and development sector is offering a public funding opportunity titled "DoD Peer Reviewed Medical Clinical Trial Award" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 12.420 Military Medical Research and Development.
- This funding opportunity was created on Jan 29, 2010 and posted on Jan 29, 2010.
- Applicants must submit their applications by May 13, 2010. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $6,600,000.00 to eligible and selected applicants.
- The number of recipients for this funding is limited to 2 candidate(s).
- Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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Opportunity Summary:
The DoD Peer Reviewed Medical Clinical Trial Award (Funding Opportunity Number W81XWH-10-PRMRP-CTA) is a U.S. Department of the Army/USAMRAA funding opportunity designed to accelerate the launch and execution of clinical trials that can quickly produce meaningful, real-world improvements for patients. The emphasis is on rapid implementation, meaning the program is looking for trials that are ready to move forward and that test interventions with a strong chance of making a significant difference in a disease or condition that falls under at least one of the congressionally directed FY10 Peer Reviewed Medical Research Program (PRMRP) topic areas. The trials may focus on prevention, detection, diagnosis, treatment, and/or quality of life, as long as the work is clearly connected to one of the FY10 PRMRP topics and is positioned to generate actionable clinical evidence.
A central requirement of this award is clear military relevance. Every application must explicitly explain how the proposed clinical trial addresses the health care needs of the Armed Forces, military family members, and/or the U.S. veteran population. This does not mean the study must enroll active-duty service members or be conducted on a military installation, but it does mean the clinical question, target condition, and expected impact must be directly tied to issues that matter for military and veteran health. The solicitation also encourages collaboration with military and/or Department of Veterans Affairs (VA) researchers and clinicians, reflecting a preference for teams that can bridge academic, civilian, and federal clinical environments. At the same time, the opportunity makes it clear that use of military populations is not required, and it strongly recommends recruiting civilian populations as an alternative when appropriate, likely to improve feasibility, enrollment speed, and generalizability while still maintaining military relevance through the condition studied and the intended impact.
From an administrative and funding standpoint, this is a discretionary research and development opportunity in the science and technology category, offered through either a cooperative agreement or a grant mechanism. The program anticipated making about two awards, with an estimated total funding level of $6.6 million, and it does not require cost sharing or matching funds. Eligibility is listed as unrestricted, meaning it is broadly open to many types of organizations (for example, academic institutions, nonprofits, for-profits, and other entities), subject to any clarifications that may have appeared in the full announcement. The opportunity was posted on January 29, 2010, with an application deadline of May 13, 2010, and it was archived on June 12, 2010. The CFDA number associated with this program is 12.420 (Military Medical Research and Development).
For applicants, the practical takeaway is that proposals needed to present a well-justified, clinically important intervention, a trial design that can be implemented quickly, and a straightforward explanation of why the results would matter to service members, their families, or veterans. Competitive applications would also be expected to show readiness factors typical for clinical trials (such as a credible recruitment plan and strong clinical oversight), and they would benefit from meaningful partnerships with military or VA clinicians even if the participants are civilians. For help accessing the full announcement or resolving submission issues, the posting provided contact points through the CDMRP and USAMRAA support channels, including PA HELP and the CDMRP eReceipt/Help Desk.
FAQs: DoD Peer Reviewed Medical Clinical Trial Award (W81XWH-10-PRMRP-CTA)
What is the DoD Peer Reviewed Medical Clinical Trial Award (PRMRP-CTA)?
The DoD Peer Reviewed Medical Clinical Trial Award (Funding Opportunity Number W81XWH-10-PRMRP-CTA) is a U.S. Department of the Army/USAMRAA funding opportunity intended to accelerate the launch and execution of clinical trials. Its purpose is to support trials that can quickly produce meaningful, real-world improvements for patients.
What is the main emphasis of this funding opportunity?
The main emphasis is rapid implementation. The program is looking for clinical trials that are ready to move forward and can be launched and executed quickly to generate actionable clinical evidence.
What kinds of clinical trials are supported under this award?
Trials may focus on prevention, detection, diagnosis, treatment, and/or quality of life, as long as the work is clearly connected to at least one congressionally directed FY10 PRMRP topic area and is positioned to produce clinically meaningful, actionable results.
Do projects have to fit within specific research topic areas?
Yes. The proposed clinical trial must address a disease or condition that falls under at least one of the congressionally directed FY10 Peer Reviewed Medical Research Program (PRMRP) topic areas.
What does "military relevance" mean for an application?
Military relevance is a central requirement. Every application must explicitly explain how the proposed clinical trial addresses the health care needs of the Armed Forces, military family members, and/or the U.S. veteran population. The connection must be clear in the clinical question, target condition, and expected impact.
Does the trial have to enroll active-duty service members to be considered militarily relevant?
No. The opportunity states that the study does not need to enroll active-duty service members or be conducted on a military installation. However, the clinical question and expected impact must still be directly tied to issues important for military and veteran health.
Are civilian participants allowed or encouraged?
Yes. The solicitation makes clear that use of military populations is not required and strongly recommends recruiting civilian populations as an alternative when appropriate, to support feasibility, enrollment speed, and generalizability while maintaining military relevance through the condition studied and intended impact.
Is collaboration with military or VA partners required?
The opportunity encourages collaboration with military and/or Department of Veterans Affairs (VA) researchers and clinicians, reflecting a preference for teams that can bridge academic, civilian, and federal clinical environments. The information provided does not state that such collaboration is strictly required.
What makes an application competitive based on the description provided?
Competitive proposals would present a well-justified, clinically important intervention; a trial design that can be implemented quickly; and a straightforward explanation of why the results matter to service members, their families, or veterans. They would also show typical clinical trial readiness factors, such as a credible recruitment plan and strong clinical oversight.
What funding mechanisms are used for this opportunity?
The opportunity is offered through either a cooperative agreement or a grant mechanism.
What type of federal opportunity is this?
It is described as a discretionary research and development opportunity in the science and technology category.
How many awards were anticipated and what was the estimated total funding?
The program anticipated making about two awards, with an estimated total funding level of $6.6 million.
Is cost sharing or matching required?
No. The opportunity does not require cost sharing or matching funds.
Who was eligible to apply?
Eligibility is listed as unrestricted, meaning it is broadly open to many types of organizations (such as academic institutions, nonprofits, for-profits, and other entities), subject to any clarifications that may have appeared in the full announcement.
When was the opportunity posted and what were the key dates?
The opportunity was posted on January 29, 2010. The application deadline was May 13, 2010. It was archived on June 12, 2010.
What is the CFDA number associated with this program?
The CFDA number associated with this program is 12.420 (Military Medical Research and Development).
Which agencies are associated with administering this opportunity?
The opportunity is associated with the U.S. Department of the Army and USAMRAA, and it references CDMRP support channels for assistance.
Where could applicants get help with the full announcement or submission issues?
The posting provided contact points through CDMRP and USAMRAA support channels, including PA HELP and the CDMRP eReceipt/Help Desk.
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