Opportunity Information: Apply for W81XWH 12 PRMRP CTA
Apply for W81XWH 12 PRMRP CTA
- The Dept. of the Army USAMRAA in the science and technology and other research and development sector is offering a public funding opportunity titled "DoD Peer Reviewed Medical Clinical Trial Award" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 12.420 Military Medical Research and Development.
- This funding opportunity was created on Mar 29, 2012 and posted on Mar 29, 2012.
- Applicants must submit their applications by Jun 26, 2012. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $6,600,000.00 to eligible and selected applicants.
- The number of recipients for this funding is limited to 2 candidate(s).
- Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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Opportunity Summary:
The DoD Peer Reviewed Medical Clinical Trial Award (PRMRP CTA), Funding Opportunity Number W81XWH-12-PRMRP-CTA, is a U.S. Department of Defense medical research funding opportunity administered by the Department of the Army through USAMRAA. It is part of the Peer Reviewed Medical Research Program (PRMRP) and is designed specifically to fund the rapid start-up and execution of clinical trials that could meaningfully change outcomes for diseases or conditions that fall under at least one of the Congressionally directed FY12 PRMRP topic areas. In practical terms, the program is looking for clinical studies that are ready to move forward quickly and that have a clear path to generating clinically useful evidence rather than early-stage lab or preclinical work.
The award supports a broad range of clinical trial types and intervention categories. Proposed trials can test promising medical products, pharmacologic agents such as drugs or biologics, medical devices, clinical guidance or care delivery approaches, and other emerging technologies or methods that could improve prevention, diagnosis, treatment, or management of relevant conditions. The opportunity is flexible in scope, allowing everything from smaller proof-of-concept efforts (including pilot studies, first-in-human studies, and Phase 0 trials) that establish feasibility or help refine the design of later-stage trials, all the way through larger, more definitive trials intended to determine efficacy in appropriate patient populations. The underlying emphasis is on generating high-impact clinical evidence with the potential to translate into real-world improvements.
A central requirement is that the research must address the healthcare needs of military service members, veterans, and/or other military beneficiaries. Importantly, applicants do not need to recruit exclusively from military populations, and use of military participants is not required, but the justification for military relevance needs to be clear and credible. This typically means the study question, condition, or intervention should map to health issues that affect these communities, or the results should be likely to improve care, readiness, recovery, or long-term health outcomes for them.
From an administrative and funding standpoint, the opportunity is categorized as discretionary funding, with awards made through cooperative agreements and/or grants under CFDA 12.420 (Military Medical Research and Development). The government anticipated making about 2 awards, with an estimated total funding amount of $6,600,000. There is no cost sharing or matching requirement, which can make the program more accessible to a wider set of institutions and investigators. Eligibility is listed as unrestricted, meaning it is generally open to any type of applicant organization, subject to any additional eligibility language in the full announcement.
Key dates for this specific posted opportunity were: Posted and created on March 29, 2012, with an application closing date of June 26, 2012, and an archive date of July 26, 2012. For technical help accessing the full announcement, the listed contact was the CDMRP Help Desk (help@cdmrp.org, 301-682-5507).
Frequently Asked Questions (FAQ)
1) What is the DoD Peer Reviewed Medical Clinical Trial Award (PRMRP CTA)?
The PRMRP Clinical Trial Award (CTA) is a U.S. Department of Defense medical research funding opportunity under the Peer Reviewed Medical Research Program (PRMRP). It is designed to fund the rapid start-up and execution of clinical trials that could meaningfully change outcomes for diseases or conditions that fall under at least one of the Congressionally directed FY12 PRMRP topic areas.
2) What is the Funding Opportunity Number (FON) for this grant?
The Funding Opportunity Number is W81XWH-12-PRMRP-CTA.
3) Who administers this funding opportunity?
This opportunity is administered by the Department of the Army through USAMRAA (U.S. Army Medical Research Acquisition Activity), on behalf of the DoD program.
4) What type of projects is the PRMRP CTA meant to support?
The program is specifically looking for clinical studies that are ready to move forward quickly and that have a clear path to generating clinically useful evidence. It is aimed at rapid clinical trial start-up and execution, rather than early-stage laboratory or preclinical research.
5) Does the PRMRP CTA only fund large, late-stage clinical trials?
No. The opportunity supports a broad range of clinical trial sizes and stages, from smaller proof-of-concept efforts (including pilot studies, first-in-human studies, and Phase 0 trials) through larger, more definitive trials intended to determine efficacy in appropriate patient populations.
6) What kinds of interventions can be tested under this opportunity?
Proposed trials can evaluate a wide range of intervention categories, including promising medical products, pharmacologic agents (such as drugs or biologics), medical devices, clinical guidance or care delivery approaches, and other emerging technologies or methods that could improve prevention, diagnosis, treatment, or management of relevant conditions.
7) What is the main goal or emphasis of the PRMRP CTA?
The main emphasis is on generating high-impact clinical evidence with the potential to translate into real-world improvements, meaning evidence that could meaningfully change outcomes for relevant diseases or conditions.
8) Do projects have to fit specific topic areas?
Yes. The clinical trial must address a disease or condition that falls under at least one of the Congressionally directed FY12 PRMRP topic areas.
9) What does “military relevance†mean for this award?
A central requirement is that the research must address the healthcare needs of military service members, veterans, and/or other military beneficiaries. The application should clearly and credibly justify why the study question, condition, or intervention is relevant to these populations and how results could improve care, readiness, recovery, or long-term health outcomes.
10) Are applicants required to recruit only military participants?
No. Applicants do not need to recruit exclusively from military populations, and use of military participants is not required. However, the proposal must include a clear and credible justification for military relevance.
11) What type of funding mechanism is used for awards?
Awards are made through cooperative agreements and/or grants.
12) Is this a discretionary or mandatory funding opportunity?
This opportunity is categorized as discretionary funding.
13) What is the CFDA number associated with this opportunity?
The CFDA number is 12.420 (Military Medical Research and Development).
14) How many awards were anticipated, and what was the estimated total funding?
The government anticipated making about 2 awards, with an estimated total funding amount of $6,600,000.
15) Is cost sharing or matching required?
No. There is no cost sharing or matching requirement.
16) Who is eligible to apply?
Eligibility is listed as unrestricted, meaning it is generally open to any type of applicant organization, subject to any additional eligibility language in the full announcement.
17) When was this opportunity posted, and what were the key dates?
The opportunity was posted and created on March 29, 2012. The application closing date was June 26, 2012, and the archive date was July 26, 2012.
18) Where can applicants get technical assistance about accessing the full announcement?
For technical help accessing the full announcement, the listed contact was the CDMRP Help Desk at help@cdmrp.org or 301-682-5507.
19) What kinds of outcomes is the program hoping trials will impact?
The program is oriented toward trials that could meaningfully change outcomes for targeted diseases or conditions, with an emphasis on clinically useful evidence and real-world improvements in prevention, diagnosis, treatment, or management.
20) Does this opportunity support clinical care delivery and guidance approaches, or only products like drugs and devices?
It supports both. In addition to drugs/biologics and devices, it can support trials evaluating clinical guidance or care delivery approaches and other emerging technologies or methods.
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