DoD Peer Reviewed Medical Clinical Trial Award | Apply Online

Opportunity Summary:

The DoD Peer Reviewed Medical Research Program (PRMRP) Clinical Trial Award is a Department of the Army (USAMRAA) funding opportunity intended to speed the launch and execution of clinical trials that could meaningfully improve prevention, diagnosis, treatment, or clinical management for diseases and conditions tied to at least one of the Congressionally directed FY2013 PRMRP Topic Areas. The emphasis is on practical, patient-focused studies that can move promising interventions into real-world testing quickly, with the expectation that results could have a significant impact on health outcomes and clinical practice.

This award supports a wide range of clinical trial types and stages. Projects can be early, smaller studies such as proof-of-concept, pilot, first-in-human, or Phase 0 trials designed to show feasibility, establish initial signals of safety or biological activity, or generate data needed to design a larger definitive study. At the other end of the spectrum, applicants may propose larger-scale trials aimed at determining efficacy in relevant patient populations. The program is designed to accommodate trials that test new products and interventions, including pharmacologic agents (drugs or biologics), medical devices, clinical guidance or care delivery approaches, and emerging technologies. In other words, proposals are not limited to a single kind of medical solution; the key is that the trial is well-justified, ready to implement, and aligned with an eligible PRMRP topic area.

A core requirement is that every proposed study must be responsive to the health care needs of U.S. military service members, Veterans, and/or their beneficiaries. Importantly, the announcement clarifies that investigators do not have to recruit exclusively from military populations (or use military sites) to qualify. The focus is on relevance and potential benefit to those communities rather than mandating that participants come from the armed forces. This allows applicants to design scientifically sound trials in broader civilian settings while still addressing conditions and needs that matter to the military and Veteran health landscape.

Administratively, this opportunity was posted May 14, 2013, with an application closing date of October 8, 2013, and it was archived on November 7, 2013. The funding opportunity number is W81XWH-13-PRMRP-CTA. The instrument types listed are cooperative agreement and grant, under the Science and Technology and other Research and Development activity category, with CFDA 12.420 (Military Medical Research and Development). The estimated total funding available was $6.6 million, with an expectation of making about two awards, and there was no cost-sharing or matching requirement. Eligibility is described as unrestricted (open to any type of entity), subject to any additional eligibility clarifications that may have appeared in the full announcement text.

For assistance accessing the full announcement, applicants were directed to the CDMRP Help Desk at 301-682-5507 or help@cdmrp.org.

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