Opportunity Information: Apply for W81XWH 13 PRMRP IIRA
Apply for W81XWH 13 PRMRP IIRA
- The Dept. of the Army USAMRAA in the science and technology and other research and development sector is offering a public funding opportunity titled "DoD Peer Reviewed Medical Investigator Initiated Research Award" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 12.420 Military Medical Research and Development.
- This funding opportunity was created on May 14, 2013 and posted on May 14, 2013.
- Applicants must submit their applications by Oct 8, 2013. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $2,677,500.00 to eligible and selected applicants.
- The number of recipients for this funding is limited to 21 candidate(s).
- Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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Opportunity Summary:
The DoD Peer Reviewed Medical Research Program (PRMRP) Investigator Initiated Research Award (IIRA) is a Department of Defense funding opportunity designed to back investigator-driven studies that can make a meaningful difference in research and/or patient care for diseases or conditions that fall under at least one of the Congressionally directed FY13 PRMRP Topic Areas. The program is intentionally broad in where ideas can come from: a new laboratory finding, population-based or epidemiologic observations, a clinicians direct experience with patients, or even well-supported anecdotal observations. What matters is that the proposed work is grounded in evidence, so applications are expected to include relevant supporting data that justify the rationale for the study, whether those data are unpublished preliminary results or already available in the scientific literature.
The scope of research supported by this award spans the full spectrum from basic science through translational research. That includes foundational laboratory investigations, preclinical studies in animal models, and studies involving human subjects, as well as work using human anatomical substances. It also allows correlative studies connected to an existing clinical trial, such as biomarker analyses or mechanistic investigations that leverage trial samples or data. A key restriction is that the award cannot be used to conduct a clinical trial itself, meaning applicants need to structure any human-focused work so it does not meet the definition of an interventional clinical trial supported by the award, even though observational studies, analyses of existing specimens, and correlative research alongside an already-running trial may be acceptable.
Administratively, this opportunity (Funding Opportunity Number W81XWH-13-PRMRP-IIRA) was offered by the Department of the Army through USAMRAA under CFDA 12.420 (Military Medical Research and Development). The funding mechanism could be either a grant or a cooperative agreement, and it fell under the Science and Technology / Research and Development activity category. The announcement anticipated approximately 21 awards with an estimated total funding level of $2,677,500, and it did not require cost sharing or matching funds. Eligibility was listed as unrestricted, meaning the competition was open broadly to applicants of any entity type, subject to any additional eligibility clarifications that may have appeared in the full announcement.
In terms of timing, the opportunity was posted May 14, 2013, and it originally closed (and ultimately closed) on October 8, 2013, with an archive date of November 7, 2013. For support accessing the full announcement or resolving submission issues, the CDMRP Help Desk was provided as the point of contact at 301-682-5507 and help@cdmrp.org.
PRMRP Investigator Initiated Research Award (IIRA) - FAQ
What is the PRMRP Investigator Initiated Research Award (IIRA)?
The Peer Reviewed Medical Research Program (PRMRP) Investigator Initiated Research Award (IIRA) is a U.S. Department of Defense funding opportunity intended to support investigator-driven studies that can make a meaningful difference in research and/or patient care for diseases or conditions aligned with at least one of the Congressionally directed FY13 PRMRP Topic Areas.
What kinds of research ideas are appropriate for this award?
The program is intentionally broad about where ideas can come from. Proposed research may be motivated by a new laboratory finding, population-based or epidemiologic observations, a clinician's direct experience with patients, or well-supported anecdotal observations, as long as the study is grounded in evidence.
Is supporting data required in the application?
Yes. Applications are expected to include relevant supporting data that justify the study rationale. Supporting evidence may include unpublished preliminary results and/or data already available in the scientific literature.
What is the overall research scope supported by the IIRA?
The award supports research across the spectrum from basic science through translational research. This includes foundational laboratory investigations, preclinical studies in animal models, studies involving human subjects, and work using human anatomical substances.
Are studies involving human subjects allowed?
Yes. Studies involving human subjects are within scope, provided the proposed work does not constitute a clinical trial funded by this award.
Can the award be used to conduct a clinical trial?
No. A key restriction is that the award cannot be used to conduct a clinical trial itself. Applicants should structure any human-focused work so it does not meet the definition of an interventional clinical trial supported by the award.
If clinical trials are not allowed, what kinds of human-focused work may still be acceptable?
The opportunity indicates that certain non-interventional approaches may be acceptable, including observational studies, analyses of existing specimens, and correlative research connected to an already-running clinical trial (for example, biomarker analyses or mechanistic investigations using trial samples or data).
Are correlative studies associated with existing clinical trials allowed?
Yes. Correlative studies linked to an existing clinical trial are explicitly allowed, such as biomarker analyses or mechanistic investigations that leverage samples or data from a trial that is already underway.
Can the research include animal models and preclinical studies?
Yes. The supported scope includes preclinical studies in animal models as well as other laboratory-based investigations.
Can the research use human anatomical substances?
Yes. Work using human anatomical substances is included within the supported scope.
What is the Funding Opportunity Number for this announcement?
The Funding Opportunity Number is W81XWH-13-PRMRP-IIRA.
Which government organization offered this opportunity?
This opportunity was offered by the Department of the Army through the U.S. Army Medical Research Acquisition Activity (USAMRAA) under the Department of Defense PRMRP.
What CFDA program is associated with this funding opportunity?
The opportunity is associated with CFDA 12.420, Military Medical Research and Development.
What type of funding mechanism was used?
The funding mechanism could be either a grant or a cooperative agreement.
What activity category did this opportunity fall under?
The opportunity fell under the Science and Technology / Research and Development activity category.
How many awards were anticipated and what was the estimated total funding?
The announcement anticipated approximately 21 awards, with an estimated total funding level of $2,677,500.
Was cost sharing or matching required?
No. The opportunity did not require cost sharing or matching funds.
Who was eligible to apply?
Eligibility was listed as unrestricted, meaning it was open broadly to applicants of any entity type, subject to any additional eligibility clarifications that may have appeared in the full announcement.
When was the opportunity posted?
The opportunity was posted on May 14, 2013.
When did the opportunity close?
The opportunity closed on October 8, 2013.
When was the opportunity archived?
The archive date was November 7, 2013.
Who can applicants contact for help with the full announcement or submission issues?
Applicants were directed to the CDMRP Help Desk for support at 301-682-5507 or help@cdmrp.org.
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