DoD Peer Reviewed Medical Research Program Clinical Trial Award | Apply Online

Frequently Asked Questions (FAQs): DoD PRMRP Clinical Trial Award (W81XWH-09-PRMRP-CTA)

What is the PRMRP Clinical Trial Award?

The Peer Reviewed Medical Research Program (PRMRP) Clinical Trial Award is a Department of the Army funding opportunity administered through the U.S. Army Medical Research Acquisition Activity (USAMRAA). It is designed to support the rapid start-up and execution of clinical trials that move promising interventions into clinical testing quickly.

What is the main purpose of this award?

The core purpose is to quickly advance interventions into a clinical testing environment, prioritizing studies that are ready to be implemented and that have a clear line of sight to meaningful, real-world clinical impact. The program emphasis is on trials intended to make a significant difference for a disease or condition aligned with at least one of the congressionally directed FY09 PRMRP topic areas.

What types of projects does this opportunity support?

This opportunity supports clinical trials that can start up and execute rapidly. It focuses on applied clinical testing rather than early exploratory work, and it is oriented toward interventions expected to produce significant clinical impact.

Does the study have to be a clinical trial?

Yes. The funding opportunity is explicitly a Clinical Trial Award and is intended to support the rapid start-up and execution of clinical trials.

What kinds of clinical goals are allowed?

The announcement allows a wide range of clinical goals, including prevention strategies, improved methods for detection or diagnosis, new or better treatments, and interventions aimed at improving quality of life.

What topic areas must the research align with?

The proposed trial must address a disease or condition that falls under at least one of the congressionally directed FY09 PRMRP topic areas. The opportunity description indicates that alignment to these topic areas is a core requirement for relevance to the program.

What does "military relevance" mean for this award?

Military relevance is a central requirement. Each application is expected to explicitly and clearly explain how the proposed clinical trial addresses the health care needs of one or more of the following groups: active duty Service members, military family members, and/or U.S. Veterans.

Do applicants have to recruit participants from military populations?

No. Recruiting from military populations is not required. The opportunity strongly recommends that applicants consider recruiting civilian participants as an alternative to support feasibility and speed of enrollment, while still ensuring the outcomes are relevant to Armed Forces and Veteran health.

Can a trial be funded if the immediate study population is civilian?

Yes. Even if the immediate study population is not military, the proposal must make a convincing case that the findings would translate to and benefit active duty Service members, military family members, and/or U.S. Veterans.

Is collaboration with military researchers or clinicians required?

Collaboration is encouraged, but not stated as required. The announcement suggests partnerships with military medical treatment facilities, DoD or VA clinicians, or investigators familiar with military health systems may strengthen the project and help ensure practical relevance and smoother translation.

Who is the sponsoring agency and who administers the program?

The sponsor is the Department of the Army (DoD). The funding opportunity is run through the U.S. Army Medical Research Acquisition Activity (USAMRAA).

What is the Funding Opportunity Number for this award?

The Funding Opportunity Number (FON) is W81XWH-09-PRMRP-CTA.

What type of funding instrument is used?

This was described as a discretionary research and development (science and technology/R&D) funding opportunity offered as either a cooperative agreement or a grant.

How many awards were expected to be made?

The program anticipated making about two awards.

What was the estimated total funding available?

The estimated total funding amount was $7,250,000.

Is cost sharing or matching required?

No. The announcement specified that there was no cost sharing or matching requirement.

Who is eligible to apply?

Eligibility was described as unrestricted, meaning it was broadly open to different entity types, as long as applicants met any additional eligibility clarifications in the full announcement.

When was the opportunity posted?

The opportunity was posted on January 29, 2009.

What was the application deadline?

The application deadline was April 16, 2009.

When was the opportunity archived?

The archive date was May 16, 2009.

What is the CFDA number associated with this program?

The CFDA number associated with the program was 12.420 (Military Medical Research and Development).

What support contacts were provided for application submission and technical help?

The announcement provided multiple support contacts, including:

• PA HELP: 301-619-7079 (cdmrp.pa@amedd.army.mil)
• eReceipt HELP: 301-682-5507 (help@cdmrp.org)
• CDMRP Help Desk (referenced as an additional support resource)

What kinds of studies are most competitive based on the description?

Based on the description, the opportunity is geared toward trials that are ready to be implemented quickly, can execute rapidly, and have a clear pathway to significant clinical impact. Applications also need a strong, explicit case for military relevance and for how results will benefit Service members, military families, and/or Veterans.

What is the overall emphasis of PRMRP in this award?

The overall emphasis is mission-driven medical needs, with a focus on translating promising interventions into practical clinical impact for conditions that align with FY09 PRMRP topic areas and that address the health care needs of military-connected populations.