Opportunity Information: Apply for W81XWH 12 PCRP HDRA

  • The Dept. of the Army USAMRAA in the science and technology and other research and development sector is offering a public funding opportunity titled "DoD Prostate Cancer Health Disparity Research Award" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 12.420 Military Medical Research and Development.
  • This funding opportunity was created on Mar 22, 2012 and posted on Mar 22, 2012.
  • Applicants must submit their applications by Aug 9, 2012. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $4,800,000.00 to eligible and selected applicants.
  • The number of recipients for this funding is limited to 5 candidate(s).
  • Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
Apply for W81XWH 12 PCRP HDRA

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Opportunity Summary:

The DoD Prostate Cancer Health Disparity Research Award (HDRA) is a Department of Defense funding opportunity administered through the U.S. Army Medical Research Acquisition Activity (USAMRAA) under the Prostate Cancer Research Program (PCRP). Its central purpose is to support prostate cancer research that directly targets health disparities, with the goal of reducing and ultimately eliminating differences in prostate cancer incidence, morbidity, and mortality across populations. The program is designed to push the field forward by backing new ideas that are grounded in innovative concepts or methods, rather than incremental extensions of existing work. While preliminary data are encouraged and can strengthen an application, they are not required, which makes this mechanism more accessible for investigators proposing early-stage, high-potential approaches.

A defining feature of this award is its explicit focus on disparity research, meaning proposals should be framed around understanding, measuring, or addressing unequal prostate cancer outcomes among different groups. The opportunity is structured to prioritize research that could make an important contribution to closing these gaps, whether the disparity is driven by biology, access to care, social determinants of health, environmental exposures, screening patterns, treatment differences, or other contributing factors. Even though the research is expected to be innovative, it must still be clearly aligned with the practical aim of producing knowledge or strategies that help reduce disparity-related burdens.

The announcement includes several options intended to broaden participation and strengthen project teams. The Qualified Collaborator Option allows applicants to request a higher level of funding when they include a collaborator whose involvement is essential to the project, meaning the work could not be accomplished without that collaborator's expertise or resources. To qualify, the collaborator must contribute in a substantial way and commit at least 10 percent level of effort to the project. This option is meant to encourage genuinely interdependent collaborations, such as pairing complementary scientific domains, accessing unique patient cohorts or datasets, leveraging specialized analytic platforms, or integrating community-engaged research capabilities that expand what the principal investigator (PI) could do alone.

The New Investigator Option is geared toward researchers who are early in their faculty appointments or still building independent careers. This pathway signals that the program is not only funding established labs but is also intentionally building the next generation of leaders in prostate cancer health disparities. In addition, the Nested Traineeship Option supports predoctoral or postdoctoral training embedded within the larger research effort. This is intended for trainees committed to becoming independent investigators in prostate cancer health disparity research, effectively combining a funded research project with structured workforce development. Taken together, these options reflect a program design that supports both scientific innovation and capacity-building in a specialized, high-need research area.

In terms of award structure, this opportunity was released as Funding Opportunity Number W81XWH-12-PCRP-HDR A (commonly abbreviated HDRA), categorized as discretionary funding in the science and technology/research and development area. The funding instrument types listed include cooperative agreements and grants. The program anticipated making about five awards, with an estimated total funding level of $4,800,000. No cost sharing or matching requirement was indicated. Eligibility was described as unrestricted, meaning it was broadly open to applicant entities, subject to any specific clarifications that may have appeared in the full announcement text.

The timeline information in the source indicates the opportunity was posted on March 22, 2012, with an original and current closing date of August 9, 2012, and an archive date of September 8, 2012. Importantly, the award mechanism does not support clinical trials, so proposed studies must be non-clinical-trial in nature even if they involve human data, biospecimens, observational research, methods development, or other non-interventional designs consistent with the solicitation rules.

For applicants who needed assistance accessing the announcement, the listed point of contact was the CDMRP Help Desk at 301-682-5507, reflecting the program's placement within the Congressionally Directed Medical Research Programs (CDMRP) ecosystem that administers many DoD biomedical research competitions.

FAQs: DoD Prostate Cancer Health Disparity Research Award (HDRA)

What is the DoD Prostate Cancer Health Disparity Research Award (HDRA)?

The HDRA is a Department of Defense (DoD) funding opportunity under the Prostate Cancer Research Program (PCRP), administered by the U.S. Army Medical Research Acquisition Activity (USAMRAA). It is intended to support prostate cancer research that directly targets health disparities with the aim of reducing and ultimately eliminating differences in prostate cancer incidence, morbidity, and mortality across populations.

What is the main purpose of this award?

The central purpose is to fund innovative prostate cancer research specifically framed around understanding, measuring, or addressing unequal prostate cancer outcomes among different groups. The work should be aligned with producing knowledge or strategies that help reduce disparity-related burdens.

What does "health disparities" mean in the context of this opportunity?

In this opportunity, disparity research focuses on unequal prostate cancer outcomes among different populations and the factors that contribute to those differences. The announcement highlights that disparities may be driven by biology, access to care, social determinants of health, environmental exposures, screening patterns, treatment differences, or other contributing factors.

What kinds of research approaches does the program want to support?

The program is designed to push the field forward by supporting new ideas grounded in innovative concepts or methods, rather than incremental extensions of existing work. While the research should be innovative, it must remain clearly connected to reducing prostate cancer disparities.

Is preliminary data required to apply?

No. Preliminary data are encouraged and may strengthen an application, but they are not required. This is intended to make the mechanism more accessible for early-stage, high-potential approaches.

Does this award support clinical trials?

No. The mechanism does not support clinical trials. Proposed studies must be non-clinical-trial in nature, even if they involve human data, biospecimens, observational research, methods development, or similar non-interventional designs consistent with the solicitation.

What are the available funding instrument types for this opportunity?

The listed funding instrument types include cooperative agreements and grants.

What is the Funding Opportunity Number for this program?

The Funding Opportunity Number is W81XWH-12-PCRP-HDRA (commonly abbreviated HDRA).

How many awards were expected, and what was the estimated funding level?

The program anticipated making about five awards, with an estimated total funding level of $4,800,000.

Is cost sharing or matching required?

No cost sharing or matching requirement was indicated for this opportunity.

Who is eligible to apply?

Eligibility was described as unrestricted, meaning it was broadly open to applicant entities, subject to any specific clarifications that may have appeared in the full announcement text.

What is the Qualified Collaborator Option?

The Qualified Collaborator Option allows applicants to request a higher level of funding when they include a collaborator whose involvement is essential to the project (meaning the work could not be accomplished without that collaborator's expertise or resources).

What makes a collaborator "qualified" under the Qualified Collaborator Option?

To qualify, the collaborator must contribute in a substantial way and commit at least 10 percent level of effort to the project. The intent is to support genuinely interdependent collaborations, such as bringing complementary scientific domains together, enabling access to unique patient cohorts or datasets, leveraging specialized analytic platforms, or integrating community-engaged research capabilities that extend what the principal investigator could do alone.

What is the New Investigator Option?

The New Investigator Option is intended for researchers who are early in their faculty appointments or still building independent careers. It reflects the program goal of developing the next generation of leaders in prostate cancer health disparities research.

What is the Nested Traineeship Option?

The Nested Traineeship Option supports predoctoral or postdoctoral training embedded within the larger research effort. It is intended for trainees committed to becoming independent investigators in prostate cancer health disparity research, combining a funded project with structured workforce development.

When was this opportunity posted, and what were the close and archive dates?

The opportunity was posted on March 22, 2012. The original and current closing date was August 9, 2012, and the archive date was September 8, 2012.

What program ecosystem is this opportunity associated with?

The opportunity sits within the Congressionally Directed Medical Research Programs (CDMRP) ecosystem, which administers many DoD biomedical research competitions.

Who can applicants contact for help accessing the announcement?

The listed point of contact for assistance was the CDMRP Help Desk at 301-682-5507.

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