Opportunity Information: Apply for W81XWH 11 PHTBI BAPHA

  • The Dept. of the Army USAMRAA in the science and technology and other research and development sector is offering a public funding opportunity titled "DoD Psychological Health/Traumatic Brain Injury Basic/Applied Psychological Health Award" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 12.420 Military Medical Research and Development.
  • This funding opportunity was created on Nov 29, 2011 and posted on Sep 15, 2011.
  • Applicants must submit their applications by Jan 6, 2012. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $16,000,000.00 to eligible and selected applicants.
  • The number of recipients for this funding is limited to 4 candidate(s).
  • Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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Opportunity Summary:

The DoD Psychological Health/Traumatic Brain Injury Basic/Applied Psychological Health Award (Funding Opportunity Number W81XWH-11-PHTBI-BAPHA) is a U.S. Department of Defense research funding opportunity administered through the Department of the Army, U.S. Army Medical Research Acquisition Activity (USAMRAA). Its central purpose is to support scientific research that improves understanding of psychological health and overall well-being among military personnel and their families. In practical terms, the program is aimed at advancing evidence that can clarify causes, risk and protective factors, assessment approaches, and potential interventions that address psychological health challenges in military-connected populations, including topics that intersect with traumatic brain injury (TBI) and related psychological outcomes.

This award mechanism supports both basic research and applied research, and it explicitly allows early phase clinical trials. That means proposals can range from foundational studies that build or test theories and mechanisms, all the way through more translational work that evaluates interventions or clinical approaches at an early stage. Regardless of where the project falls on that spectrum, competitiveness hinges on strong scientific reasoning: applicants are expected to present a clear, logically constructed argument for why the study is needed and how it fits into what is already known. The solicitation emphasizes that the scientific rationale should be grounded in a critical review and analysis of the existing literature, not just a general statement of importance. Proposals are expected to be driven by a well-formulated, testable hypothesis tied directly to that rationale.

A key requirement is the distinction between basic and applied submissions with respect to supporting evidence. For applied research applications, preliminary data is required. This signals that the funder wants applied projects to be backed by prior results showing feasibility or early indications that the approach is scientifically and practically viable. Basic research is still expected to be rigorous and hypothesis-driven, but the solicitation highlights preliminary data specifically as a requirement for applied research, reflecting a preference for applied work that is ready to move forward with a credible foundation.

From an administrative standpoint, the opportunity was offered under discretionary funding and could be made as either a grant or a cooperative agreement, which typically indicates that some projects may involve more active involvement or coordination with the funding agency depending on the chosen instrument and project needs. The activity category is Science and Technology and other Research and Development. The program anticipated making about four awards, with an estimated total funding amount of $16,000,000, indicating a relatively selective competition with potentially substantial individual award sizes depending on project scope and budgeting.

Eligibility was listed as unrestricted, meaning any type of entity could apply, subject to any additional eligibility clarifications in the full announcement. There was no cost sharing or matching requirement, which reduces barriers for applicants who might not have institutional resources to provide matching funds. The listing is associated with CFDA number 12.420 (Military Medical Research and Development), aligning it with DoD medical and health-related research priorities.

Key dates included a posted date of September 15, 2011, with an original closing date of December 30, 2011, later extended to a current closing date of January 6, 2012. The archive date was January 29, 2012, meaning it is no longer open, but the details remain useful as a guide to the program’s expectations and structure for similar future DoD psychological health and TBI-related research solicitations. For access issues related to the full announcement at the time, the contact point provided was the CDMRP Help Desk at 301-682-5507, reflecting that this opportunity aligns with the Congressionally Directed Medical Research Programs (CDMRP) ecosystem even though the administering office is USAMRAA.

FAQs: DoD Psychological Health/Traumatic Brain Injury Basic/Applied Psychological Health Award (W81XWH-11-PHTBI-BAPHA)

What is this funding opportunity?

This is a U.S. Department of Defense (DoD) research funding opportunity titled the Psychological Health/Traumatic Brain Injury (PH/TBI) Basic/Applied Psychological Health Award. The Funding Opportunity Number is W81XWH-11-PHTBI-BAPHA.

Which agency administers the award?

The opportunity is administered through the Department of the Army, U.S. Army Medical Research Acquisition Activity (USAMRAA).

What is the main purpose of the program?

The central purpose is to support scientific research that improves understanding of psychological health and overall well-being among military personnel and their families.

What kinds of research topics does the program aim to support?

The program is aimed at advancing evidence related to psychological health challenges in military-connected populations, including research that clarifies causes, risk factors, protective factors, assessment approaches, and potential interventions. It also includes topics that intersect with traumatic brain injury (TBI) and related psychological outcomes.

Does the award support basic research, applied research, or both?

Both. The mechanism supports basic research and applied research.

Are clinical trials allowed under this award?

Yes. The solicitation explicitly allows early phase clinical trials.

What does it mean that early phase clinical trials are allowed?

It means proposals may include translational work that evaluates interventions or clinical approaches at an early stage, rather than being limited to non-clinical or purely observational studies.

How important is the scientific rationale in a competitive application?

It is central to competitiveness. Applicants are expected to present a clear, logically constructed argument for why the study is needed and how it fits into what is already known.

What does the solicitation expect regarding the literature review?

The scientific rationale should be grounded in a critical review and analysis of the existing literature, not simply a general statement that the topic is important.

Does the program require a hypothesis?

Yes. Proposals are expected to be driven by a well-formulated, testable hypothesis that is tied directly to the scientific rationale.

Is preliminary data required?

Preliminary data is specifically required for applied research applications. Basic research is still expected to be rigorous and hypothesis-driven, but the solicitation highlights preliminary data as a requirement for applied submissions.

Why does the program require preliminary data for applied research?

Based on the opportunity description, this requirement signals an expectation that applied projects are supported by prior results demonstrating feasibility or early indications that the approach is scientifically and practically viable.

What type of funding instrument is used (grant or cooperative agreement)?

Awards could be made as either a grant or a cooperative agreement.

What is the practical difference between a grant and a cooperative agreement in this listing?

The listing indicates that some projects may involve more active involvement or coordination with the funding agency depending on the instrument and project needs.

What is the activity category for this opportunity?

The activity category is Science and Technology and other Research and Development.

How many awards were expected?

The program anticipated making about four awards.

What was the estimated total funding amount?

The estimated total funding amount was $16,000,000.

Does the opportunity indicate whether the competition is selective?

Yes. With an expectation of about four awards and a defined total funding amount, the competition appears relatively selective.

Who was eligible to apply?

Eligibility was listed as unrestricted, meaning any type of entity could apply, subject to any additional eligibility clarifications in the full announcement.

Was cost sharing or matching required?

No. There was no cost sharing or matching requirement.

What CFDA number is associated with this opportunity?

The listing is associated with CFDA number 12.420, titled Military Medical Research and Development.

What were the key dates for this opportunity?

The posted date was September 15, 2011. The original closing date was December 30, 2011, and it was extended to a current closing date of January 6, 2012. The archive date was January 29, 2012.

Is this opportunity still open?

No. The archive date indicates it is no longer open for applications.

If it is archived, why might the details still be useful?

The details can still serve as a guide to the program expectations and structure for similar future DoD psychological health and TBI-related research solicitations.

Is this opportunity connected to CDMRP?

Yes. The contact point referenced the CDMRP Help Desk, indicating alignment with the Congressionally Directed Medical Research Programs (CDMRP) ecosystem, even though USAMRAA is the administering office.

Who was the contact for access issues related to the full announcement?

The contact listed for access issues was the CDMRP Help Desk at 301-682-5507.

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