Opportunity Information: Apply for W81XWH 16 PHTBIRP CR3A

  • The DOD-AMRAA in the science and technology and other research and development sector is offering a public funding opportunity titled "DoD Psychological Health/Traumatic Brain Injury Cognitive Resilience and Readiness Research Award" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 12.420.
  • This funding opportunity was created on May 13, 2016 and posted on May 13, 2016.
  • Applicants must submit their applications by Sep 07, 2016. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The number of recipients for this funding is limited to 2 candidate(s).
  • Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
Apply for W81XWH 16 PHTBIRP CR3A

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Opportunity Summary:

The Department of Defense Psychological Health/Traumatic Brain Injury Research Program (PH/TBIRP) Cognitive Resilience and Readiness Research Award (CR3A) is a FY16 funding opportunity aimed at improving how the military assesses, builds, and sustains cognitive performance in Service members and related high-demand specialty occupations. The core intent is to fund research that clarifies which scientific and biomedical factors shape cognitive skills, how those factors correlate with measurable performance, and how they can be leveraged to enhance cognitive assessment, training, and readiness in ways that protect health and sustain operational performance. The program is framed around practical outcomes: it is looking for solutions that can move beyond theory and be translated into real-world military training and practice, ideally with minimal disruption to existing routines.

A central emphasis of the CR3A is cognitive resilience and readiness, meaning approaches that help personnel maintain or improve critical mental functions under stress, fatigue, operational pressure, or other military-relevant demands, while also helping prevent military-relevant psychological health problems. The opportunity encourages novel, noninvasive approaches that can be integrated into current systems rather than requiring major changes to how units train or operate. In other words, applicants are expected to design work that can realistically fit into the military environment and show a clear path from research setting to use in the field, with an added expectation that the work could provide broader public benefit beyond the military.

In terms of what types of studies are allowed, the mechanism supports both applied (preclinical) research and clinical trials, but only when they squarely address the specific FY16 CR3A topic areas related to prevention of psychological health issues and enhancement of operational performance. The announcement explicitly signals what not to propose: research outside the defined FY16 topic areas should be avoided, and studies centered on post-injury diagnosis and treatment are out of scope for this particular award. Likewise, animal research is not aligned with the intent of the mechanism, so proposals relying on animal models would not be considered a good fit.

Administratively, this opportunity was posted May 13, 2016, and closed September 7, 2016, under Funding Opportunity Number W81XWH-16-PHTBIRP-CR3A. The sponsoring agency is DOD-AMRAA, and awards may be made as grants or cooperative agreements within the Science and Technology / Research and Development category (CFDA 12.420). Eligibility is described as unrestricted (open to any entity type, subject to any additional eligibility clarifications in the full text). The expected number of awards was two, and the listing did not specify an award ceiling. Overall, the CR3A is best understood as a targeted DoD investment in deployable, minimally disruptive, human-focused research that strengthens cognitive performance and resilience for military readiness while offering potential spillover benefits to civilian applications.

Frequently Asked Questions (FAQs)

What is the CR3A funding opportunity?

The Cognitive Resilience and Readiness Research Award (CR3A) is a funding opportunity under the Department of Defense Psychological Health/Traumatic Brain Injury Research Program (PH/TBIRP). It is a FY16 opportunity focused on improving how the military assesses, builds, and sustains cognitive performance in Service members and other high-demand specialty occupations.

What is the main goal of this award?

The core goal is to fund research that identifies the scientific and biomedical factors that shape cognitive skills, links those factors to measurable performance, and uses that understanding to improve cognitive assessment, training, and readiness in ways that protect health and sustain operational performance.

What does "cognitive resilience and readiness" mean in this program?

Within CR3A, cognitive resilience and readiness refers to approaches that help personnel maintain or improve critical mental functions under military-relevant demands such as stress, fatigue, and operational pressure, while also supporting prevention of military-relevant psychological health problems.

What kinds of outcomes is the program looking for?

The program emphasizes practical, deployable outcomes rather than theory alone. Proposed work should show a clear path to translation into real-world military training and practice, ideally with minimal disruption to existing routines and systems.

What types of approaches are encouraged?

The opportunity encourages novel, noninvasive approaches that can be integrated into current military systems. Proposals are expected to fit realistically into the military environment rather than requiring major changes to how units train or operate.

Is the award focused on prevention, treatment, or both?

This award is oriented toward prevention of psychological health issues and enhancement of operational performance. Studies centered on post-injury diagnosis and treatment are described as out of scope for this particular mechanism.

Are clinical trials allowed under this mechanism?

Yes. The mechanism supports both applied (preclinical) research and clinical trials, but only when they directly address the specific FY16 CR3A topic areas related to prevention of psychological health issues and enhancement of operational performance.

Is applied (preclinical) research allowed?

Yes. Applied (preclinical) research is supported, as long as it aligns with the FY16 CR3A topic areas and the program intent to produce practical, translatable outcomes for military readiness and cognitive resilience.

Are animal studies allowed?

Animal research is not aligned with the intent of this mechanism. Proposals relying on animal models would not be considered a good fit for CR3A as described.

What kinds of proposals are explicitly discouraged?

The announcement indicates that applicants should avoid (1) research outside the defined FY16 CR3A topic areas, (2) studies focused on post-injury diagnosis and treatment, and (3) animal-model-based research.

Who is the target population for the research?

The focus is on Service members and related high-demand specialty occupations, with an emphasis on maintaining or improving cognitive performance under operationally relevant conditions.

What makes a proposal a strong fit for CR3A based on the description?

A strong fit would be human-focused, aimed at cognitive performance and resilience, noninvasive, designed to integrate into existing military training and operational systems, and built around a clear plan for translating findings into field use with minimal disruption.

Does the program expect benefits beyond the military?

Yes. In addition to improving military readiness, the description notes an expectation that the work could provide broader public benefit beyond the military.

What agency sponsors this opportunity?

The sponsoring agency is DOD-AMRAA (U.S. Department of Defense, U.S. Army Medical Research Acquisition Activity).

What is the Funding Opportunity Number for this award?

The Funding Opportunity Number is W81XWH-16-PHTBIRP-CR3A.

When was this opportunity posted and when did it close?

It was posted on May 13, 2016, and closed on September 7, 2016.

What type of award instrument may be used?

Awards may be made as grants or cooperative agreements.

What is the program category and CFDA number?

The listing places the opportunity in the Science and Technology / Research and Development category, with CFDA 12.420.

Who is eligible to apply?

Eligibility is described as unrestricted, meaning it is open to any entity type, subject to any additional eligibility clarifications that may appear in the full text of the opportunity.

How many awards were expected?

The expected number of awards was two.

Is there a stated maximum award amount (ceiling)?

No award ceiling was specified in the listing information provided.

Is this opportunity primarily about improving assessment, training, or both?

Both. The intent includes clarifying factors that shape cognitive skills and linking them to measurable performance so they can be leveraged to enhance cognitive assessment, training, and readiness.

Does the opportunity prioritize work that fits into existing military routines?

Yes. The description emphasizes solutions that can be integrated into current systems and used in the field with minimal disruption to existing training and operational practices.

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