Opportunity Information: Apply for W81XWH 09 TSCRP CARTA
Apply for W81XWH 09 TSCRP CARTA
- The Dept. of the Army USAMRAA in the science and technology and other research and development sector is offering a public funding opportunity titled "DOD Tuberous Sclerosis Complex Career Transition Award" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 12.420 Military Medical Research and Development.
- This funding opportunity was created on Feb 2, 2009 and posted on Feb 2, 2009.
- Applicants must submit their applications by Apr 14, 2009. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $500,000.00 to eligible and selected applicants.
- The number of recipients for this funding is limited to 1 candidate(s).
- Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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Opportunity Summary:
The DOD Tuberous Sclerosis Complex Career Transition Award (TSCRP CARTA; Funding Opportunity Number W81XWH 09 TSCRP CARTA) is a Department of the Army, USAMRAA funding opportunity designed to help tuberous sclerosis complex (TSC) researchers move from postdoctoral training into an independent academic position. The core purpose is to provide structured, continuous support across a key career inflection point where many early-career scientists otherwise face gaps in funding, mentoring, and protected research time. Under this mechanism, the postdoctoral candidate is treated as the Principal Investigator (PI), which emphasizes independence and leadership early while still requiring strong guidance during the mentored phase.
The award is structured to cover up to four years total, split into two phases: up to the last two years of a postdoctoral fellowship followed by up to the first two years in a faculty-level independent position. Applicants are expected to present a clear and credible career transition and development plan that explains how they will use the mentored period to build skills, generate publishable results, and position themselves competitively for an independent appointment, and then how they will establish an independent research program during the faculty phase. A key requirement is a named mentor who commits to supporting and guiding the PI during the postdoctoral portion of the award, underscoring that the mechanism blends mentorship with a strong expectation of progression toward independence.
From a scientific standpoint, the program requires preliminary data that are relevant both to TSC research and to the proposed project, signaling that proposals should be grounded in feasibility and demonstrate momentum rather than being purely exploratory. The opportunity explicitly does not allow clinical trials under this award mechanism; applicants who intend to run a clinical trial are directed instead to use the Clinical and Translational Research Award mechanism. In practical terms, this makes CARTA more oriented toward foundational, mechanistic, preclinical, or translational work that stops short of conducting a regulated trial.
Administratively, this is a discretionary funding opportunity offered as a grant/cooperative agreement within the Science and Technology and other Research and Development activity category, associated with CFDA 12.420 (Military Medical Research and Development). The estimated total funding listed is $500,000 with an expectation of one award, and there is no cost sharing or matching requirement. Eligibility is listed as unrestricted (open to any type of entity), subject to any additional eligibility clarifications in the full announcement. The opportunity was posted February 2, 2009, with an original and current closing date of April 14, 2009, and an archive date of May 14, 2009.
For applicant support, the announcement provides contacts for accessing the full program materials and for submission help, including PA HELP (301-619-7079; cdmrp.pa@amedd.army.mil) and the eReceipt/CDMRP Helpdesk (301-682-5507; help@cdmrp.org).
FAQs: DOD Tuberous Sclerosis Complex Career Transition Award (TSCRP CARTA)
What is the DOD Tuberous Sclerosis Complex Career Transition Award (TSCRP CARTA)?
The TSCRP CARTA is a Department of the Army, USAMRAA funding opportunity intended to help tuberous sclerosis complex (TSC) researchers transition from postdoctoral training into an independent academic position. It is designed to provide structured, continuous support across the career stage where early-career scientists often experience gaps in funding, mentoring, and protected research time.
What is the Funding Opportunity Number for this award?
The Funding Opportunity Number listed for this opportunity is W81XWH 09 TSCRP CARTA.
Who is the sponsoring/funding organization?
The opportunity is offered by the Department of the Army through USAMRAA (U.S. Army Medical Research Acquisition Activity).
What is the main purpose of this award mechanism?
The core purpose is to support a postdoctoral researcher through a key career transition point by providing continuous funding and a structured plan that spans both a mentored postdoctoral period and an early independent faculty period.
How long can the award last?
The award can provide support for up to four years total.
How is the award structured across the four years?
The structure includes up to the last two years of a postdoctoral fellowship (mentored phase) followed by up to the first two years in a faculty-level independent position (independent phase).
Is the applicant considered the Principal Investigator (PI) under this mechanism?
Yes. Under this mechanism, the postdoctoral candidate is treated as the Principal Investigator (PI), emphasizing early independence and leadership while still requiring guidance during the mentored phase.
What is required in the career transition and development plan?
Applicants are expected to present a clear and credible career transition and development plan explaining how the mentored period will be used to build skills, generate publishable results, and become competitive for an independent appointment, and then how the applicant will establish an independent research program during the faculty phase.
Is a mentor required?
Yes. A named mentor is required and must commit to supporting and guiding the PI during the postdoctoral portion of the award.
What role does mentorship play in this program?
The mechanism blends mentorship with a strong expectation that the PI will progress toward independence, with mentorship specifically emphasized during the postdoctoral (mentored) phase.
Is preliminary data required?
Yes. The program requires preliminary data that are relevant both to TSC research and to the proposed project.
What does the preliminary data requirement imply about the type of project proposed?
It signals that proposals should be grounded in feasibility and show momentum (for example, evidence supporting the approach and relevance to TSC), rather than being purely exploratory.
Are clinical trials allowed under the CARTA mechanism?
No. Clinical trials are explicitly not allowed under this award mechanism.
If an applicant wants to run a clinical trial, what mechanism should they use instead?
Applicants intending to conduct a clinical trial are directed to use the Clinical and Translational Research Award mechanism instead of CARTA.
What kinds of research are most aligned with CARTA, based on the announcement?
Because clinical trials are not allowed and preliminary data are required, the opportunity is oriented toward foundational, mechanistic, preclinical, or translational work related to TSC that stops short of conducting a regulated clinical trial.
What type of funding instrument is this opportunity?
The announcement describes it as a discretionary funding opportunity offered as a grant/cooperative agreement within the Science and Technology and other Research and Development activity category.
What CFDA number is associated with this opportunity?
The opportunity is associated with CFDA 12.420 (Military Medical Research and Development).
What is the estimated total funding amount and expected number of awards?
The estimated total funding listed is $500,000, with an expectation of one award.
Is cost sharing or matching required?
No. The announcement states there is no cost sharing or matching requirement.
Who is eligible to apply?
Eligibility is listed as unrestricted (open to any type of entity), subject to any additional eligibility clarifications in the full announcement.
When was this opportunity posted?
The opportunity was posted on February 2, 2009.
What is the application closing date?
The original and current closing date listed is April 14, 2009.
What is the archive date?
The archive date listed is May 14, 2009.
Where can applicants get help accessing full program materials?
Applicants can contact PA HELP at 301-619-7079 or by email at cdmrp.pa@amedd.army.mil for help accessing full program materials.
Where can applicants get technical help with submission (eReceipt/CDMRP)?
Applicants can contact the eReceipt/CDMRP Helpdesk at 301-682-5507 or by email at help@cdmrp.org for submission assistance.
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