Opportunity Information: Apply for W81XWH 11 TSCRP CARTA
Apply for W81XWH 11 TSCRP CARTA
- The Dept. of the Army USAMRAA in the science and technology and other research and development sector is offering a public funding opportunity titled "DOD Tuberous Sclerosis Complex Career Transition Award" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 12.420 Military Medical Research and Development.
- This funding opportunity was created on Apr 28, 2011 and posted on Apr 28, 2011.
- Applicants must submit their applications by Aug 1, 2011. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $500,000.00 to eligible and selected applicants.
- The number of recipients for this funding is limited to 1 candidate(s).
- Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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Opportunity Summary:
The DOD Tuberous Sclerosis Complex (TSC) Career Transition Award is a funding opportunity under the Army-managed Tuberous Sclerosis Complex Research Program (TSCRP), which was created in 2002 to drive innovative research that reduces the real-world clinical burden of TSC. The program is built around two linked goals: improving scientific understanding of how TSC develops and progresses (its pathogenesis), and translating that knowledge into better care and outcomes for people living with TSC. In practical terms, the award is meant to help promising TSC-focused scientists move from mentored postdoctoral training into an independent faculty-level research position without losing momentum, funding continuity, or research direction during that vulnerable career stage.
This mechanism supports a structured four-year transition period: up to two years covering the final phase of postdoctoral training, followed by up to two additional years after the investigator secures a faculty-level independent appointment. A key feature is that the postdoctoral fellow, not the mentor, is designated as the Principal Investigator (PI), which signals that the applicant is expected to be taking ownership of the research vision and building toward independence. At the same time, the award requires a clearly identified mentor for the postdoctoral portion of the project who will provide guidance, training support, and oversight, with the explicit intent of preparing the PI to lead an independent research program.
Applications are expected to be more than just a research proposal. They must include a well-developed career transition and career development plan that explains how the applicant will acquire the skills, track record, and professional positioning needed to become independent. The research itself must be directly relevant to TSC, and the announcement emphasizes that preliminary data are required. That requirement sets an expectation that the project is already grounded in feasible early findings rather than being purely speculative, and that it has a credible pathway to producing impactful results within the award period.
Administratively, this opportunity was posted April 28, 2011, with an original and final closing date of August 1, 2011, and an archive date of August 31, 2011. It was offered by the Department of the Army through USAMRAA under Funding Opportunity Number W81XWH-11-TSCRP-CARTA. The funding instrument type is listed as a cooperative agreement and grant within the science and technology and other research and development category. The estimated total funding for the opportunity was $500,000, with an expectation of one award, and it carried no cost sharing or matching requirement. Eligibility was described as unrestricted (open to any type of entity), subject to any additional eligibility clarifications in the full announcement. For support accessing the full announcement or using the submission systems, the notice directs applicants to the CDMRP help resources (PA HELP and eReceipt HELP) at 301-682-5507 or help@cdmrp.org.
FAQs: DOD Tuberous Sclerosis Complex (TSC) Career Transition Award (CARTA)
1. What is the DOD Tuberous Sclerosis Complex (TSC) Career Transition Award?
The DOD Tuberous Sclerosis Complex (TSC) Career Transition Award is a funding opportunity under the Army-managed Tuberous Sclerosis Complex Research Program (TSCRP). It is designed to help promising TSC-focused scientists move from mentored postdoctoral training into an independent faculty-level research position while maintaining research momentum, continuity of funding, and continuity of research direction.
2. What is the purpose of the Tuberous Sclerosis Complex Research Program (TSCRP)?
The TSCRP was created in 2002 to drive innovative research that reduces the real-world clinical burden of TSC. The program is built around two linked goals: (1) improving scientific understanding of how TSC develops and progresses (its pathogenesis), and (2) translating that knowledge into better care and outcomes for people living with TSC.
3. Who is this award intended to support?
This award is intended to support scientists who are in the postdoctoral stage and are transitioning to an independent, faculty-level research position, specifically with a focus on TSC-related research.
4. How long is the supported transition period?
The mechanism supports a structured four-year transition period.
5. How is the four-year award period structured?
The award can support up to two years covering the final phase of postdoctoral training, followed by up to two additional years after the investigator secures a faculty-level independent appointment.
6. Who is designated as the Principal Investigator (PI) for this award?
A key feature of this mechanism is that the postdoctoral fellow (not the mentor) is designated as the Principal Investigator (PI), reflecting the expectation that the applicant is taking ownership of the research vision and building toward independence.
7. Is a mentor required?
Yes. The award requires a clearly identified mentor for the postdoctoral portion of the project. The mentor is expected to provide guidance, training support, and oversight, with the explicit intent of preparing the PI to lead an independent research program.
8. What must be included in the application beyond the research proposal?
Applications are expected to include a well-developed career transition and career development plan. This plan should describe how the applicant will acquire the skills, track record, and professional positioning needed to become independent.
9. What research topics are considered responsive to this opportunity?
The research must be directly relevant to tuberous sclerosis complex (TSC) and aligned with TSCRP goals focused on understanding TSC pathogenesis and translating knowledge into better care and outcomes.
10. Are preliminary data required?
Yes. The announcement emphasizes that preliminary data are required, signaling that the project is expected to be grounded in feasible early findings and not be purely speculative.
11. What does the preliminary data requirement imply about project readiness?
It implies that the proposed work should already have credible early evidence supporting feasibility and that it should have a realistic pathway to producing impactful results within the award period.
12. What agency offered this funding opportunity?
The opportunity was offered by the Department of the Army through USAMRAA under the Army-managed TSCRP.
13. What is the Funding Opportunity Number for this announcement?
The Funding Opportunity Number is W81XWH-11-TSCRP-CARTA.
14. What type of funding instrument is used?
The funding instrument type is listed as a cooperative agreement and grant within the science and technology and other research and development category.
15. What was the estimated total funding available?
The estimated total funding for the opportunity was $500,000.
16. How many awards were expected to be made?
The notice indicated an expectation of one award.
17. Is cost sharing or matching required?
No. The opportunity carried no cost sharing or matching requirement.
18. Who was eligible to apply?
Eligibility was described as unrestricted (open to any type of entity), subject to any additional eligibility clarifications in the full announcement.
19. When was this opportunity posted and when did it close?
This opportunity was posted on April 28, 2011. The original and final closing date was August 1, 2011.
20. When was the opportunity archived?
The archive date was August 31, 2011.
21. Where can applicants get help accessing the full announcement or using the submission systems?
The notice directs applicants to CDMRP help resources (PA HELP and eReceipt HELP). Support is available at 301-682-5507 or by email at help@cdmrp.org.
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